Yoga reduces premenstrual syndrome symptoms and modulates hormonal and inflammatory blood parameters: single-blind randomized controlled trial

Abstract

Objective: This study aimed to investigate the effect of yoga on premenstrual syndrome(PMS) symptoms, pain, blood cell counts, and inflammation parameters in women with PMS. Methods: This study was conducted as a randomized controlled, single-blind trial in the gynecology and obstetrics clinic of a hospital in Istanbul between September 2021-June 2022. In the study, 131 women who presented with complaints of PMS and were diagnosed with PMS and met the sampling selection criteria (Group A yoga group n=65,Group B control group n=66) were randomized into two groups. The intervention group underwent a total of 24 yoga sessions, three days a week, for 8 weeks. Data from the included women were obtained via Personal Information Form, Visual Analog Scale (VAS), Premenstrual Syndrome Scale (PMSS), and blood sample including blood count and inflammation parameters. Results: The yoga group demonstrated a significant and progressive reduction in total PMS severity scores, whereas no significant change was observed in the control group over time. In addition, women in the intervention group showed significant reductions across multiple PMS symptom domains, including affective, somatic, and behavioral symptoms, as well as lower pain intensity scores, while no comparable changes were detected in the control group. The yoga intervention was also associated with significant improvements in hormonal, hematological, and inflammatory parameters. Conclusion: These findings suggest that yoga may represent a safe, non-pharmacological, and accessible complementary approach for the management of premenstrual syndrome, with beneficial effects on symptom severity, pain perception, and physiological regulation.

Keywords

• Premenstrual Syndrome
• Yoga
• Pain
• Inflammation
• Blood Cell Count

Yoga, premenstrüel sendrom belirtilerini azaltır ve hormonal ve inflamatuar kan parametrelerini düzenler: tek kör randomize kontrollü çalışma

Abstract

Amaç: Bu çalışmanın amacı, yoganın premenstrüel sendrom(PMS) belirtileri, ağrı, kan hücre sayımları ve inflamasyon parametreleri üzerindeki etkisini incelemektir. Yöntem: Çalışma, Eylül 2021–Haziran 2022 tarihleri arasında İstanbul’daki bir hastanenin jinekoloji ve obstetri kliniğinde randomize kontrollü, tek kör olarak yürütülmüştür. Çalışmaya PMS şikâyeti olan ve PMS tanısı konulan 131 kadın dahil edilmiştir (Grup A: yoga grubu n=65, Grup B: kontrol grubu n=66). Katılımcılar iki gruba randomize edilmiştir. Müdahale grubuna toplam 8 hafta boyunca, haftada üç gün, 24 yoga seansı uygulanmıştır. Veriler Kişisel Bilgi Formu, Görsel Analog Skalası (VAS), Premenstrüel Sendrom Skalası (PMSS) ve kan sayımı ile inflamasyon parametrelerini içeren kan örnekleri ile toplanmıştır. Bulgular: Yoga grubunda toplam PMS şiddet skorlarında anlamlı ve kademeli bir azalma saptanırken, kontrol grubunda zaman içinde istatistiksel olarak anlamlı bir değişiklik izlenmedi. Ayrıca müdahale grubundaki kadınlarda; duygusal, somatik ve davranışsal semptomlar dâhil olmak üzere birden fazla PMS semptom alanında anlamlı azalmalar ve ağrı şiddetinde belirgin düşüş gözlendi. Buna karşılık kontrol grubunda benzer değişiklikler tespit edilmedi. Yoga müdahalesi ayrıca hormonal, hematolojik ve inflamatuvar parametrelerde anlamlı iyileşmeler ile ilişkili bulundu. Sonuç: Bu bulgular, yoganın premenstrüel sendromun yönetiminde güvenli, farmakolojik olmayan ve kolay erişilebilir tamamlayıcı bir yaklaşım olabileceğini; semptom şiddeti, ağrı algısı ve fizyolojik düzenlenme üzerinde olumlu etkiler sağlayabileceğini düşündürmektedir.

Keywords

• Premenstrüel Sendrom
• Yoga
• Ağrı
• İnflamasyon
• Kan Hücre Sayımı

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