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Developmental defects of enamel as a bridge between medicine and dentistry

Year 2026, Volume: 7 Issue: 1, 57 - 59, 06.01.2026

Abstract

Developmental defects of enamel (DDEs) are permanent disturbances of enamel formation reflecting systemic insults during prenatal, perinatal, and early childhood periods. Although managed within dentistry, their systemic background is often overlooked in medical care. This letter addresses the gap between medicine and dentistry in evaluating early-life conditions and asks whether DDEs should be reconsidered as part of a child’s medical history rather than isolated dental findings. We argue that limited interprofessional communication contributes to delayed prevention and fragment-ed follow-up. Focusing on pregnancy and early childhood, we call for a multidisciplinary medical–dental approach to strengthen integrated child healthcare.

References

  • 1. Hung M, Birmingham WC, Tucker M, Schwartz C, Mohajeri A. Integrating Dentistry into Interprofes-sional Healthcare: A Scoping Review on Advancing Collaborative Practice and Patient Outcomes. Healthcare (Basel), 2025;13(21):2780.
  • 2. Christian B, George A, Veginadu P, Villarosa A, Makino Y, Kim WJ, et al. Strategies to integrate oral health into primary care: a systematic review. BMJ open, 2023;13(7):e070622.
  • 3. Seow WK. Developmental defects of enamel and dentine: challenges for basic science research and clinical management. Aust Dent J. 2014;59(1):143–54.
  • 4. Brook AH. Multilevel complex interactions between genetic, epigenetic and environmental factors in the aetiology of anomalies of dental development. Arch Oral Biol. 2009;54(1):3–17.
  • 5. Suckling GW. Developmental defects of enamel—historical and present-day perspectives of their pathogenesis. Adv Dent Res. 1989;3(2):87–94.
  • 6. Jacobsen PE, Henriksen TB, Haubek D, Østergaard JR. Developmental enamel defects in children prena-tally exposed to anti-epileptic drugs. PLoS One, 2013;8(3):e58213.
  • 7. Alaluusua S, Lukinmaa PL. Developmental dental toxicity of dioxin and related compounds—a re-view. Int Dent J. 2006;56(6):323-331.
  • 8. Alraddadi WH, Alsulami YF, Alsubhi AA, et al. What is the impact of stress on the development of molar incisor hypomineralization (MIH): a system-atic review. Saudi Dent J. 2025;37(4):17.
  • 9. Babajko S, Chaussain C, Jedeon K. Relations be-tween developmental dental defects and exposure to environmental toxicants exhibiting endocrine dis-rupting activity. In: Annales d'Endocrinologie, El-sevier Masson, 2025. p. 101765.
  • 10. Sezer B, Kaya R, Kodaman Dokumacıgil N, et al. Assessment of the oral health status of children with chronic kidney disease. Pediatr Nephrol. 2023;38:269–77.
  • 11. Laniado N, Cloidt M, Altonen B, Badner V. Interpro-fessional oral health collaboration: a survey of knowledge and practice behaviors of hospital-based primary care medical providers in New York city. Adv. medical educ. pract. 2021;1211-1218.

Gelişimsel mine defektleri: tıp ve diş hekimliği arasında bir köprü

Year 2026, Volume: 7 Issue: 1, 57 - 59, 06.01.2026

Abstract

Gelişimsel mine defektleri (GMD), prenatal, perinatal ve erken çocukluk dönemlerinde ortaya çıkan sistemik etkileri yansıtan, mine oluşumundaki kalıcı bozukluklardır. Klinik olarak sıklıkla diş hekimliği kapsamında ele alınmalarına karşın, sistemik arka planları tıbbi bakımda çoğu zaman göz ardı edilmektedir. Bu mektup, erken yaşam dönemine ait sistemik durumların değerlendirilmesinde tıp ve diş hekimliği arasındaki boşluğu ele almakta ve GMD’lerin izole dental bulgular yerine çocuğun tıbbi öyküsünün bir parçası olarak değerlendirilmesini tartışmaktadır. Sınırlı meslekler arası iletişimin gecikmiş koruyucu yaklaşımlara ve parçalı izleme yol açtığını savunuyoruz. Gebe-lik ve erken çocukluk dönemine odaklanarak, çocuk sağlığını güçlendirmek için multidisipliner bir tıp–diş hekimliği yaklaşımı çağrısında bulunuyoruz.

References

  • 1. Hung M, Birmingham WC, Tucker M, Schwartz C, Mohajeri A. Integrating Dentistry into Interprofes-sional Healthcare: A Scoping Review on Advancing Collaborative Practice and Patient Outcomes. Healthcare (Basel), 2025;13(21):2780.
  • 2. Christian B, George A, Veginadu P, Villarosa A, Makino Y, Kim WJ, et al. Strategies to integrate oral health into primary care: a systematic review. BMJ open, 2023;13(7):e070622.
  • 3. Seow WK. Developmental defects of enamel and dentine: challenges for basic science research and clinical management. Aust Dent J. 2014;59(1):143–54.
  • 4. Brook AH. Multilevel complex interactions between genetic, epigenetic and environmental factors in the aetiology of anomalies of dental development. Arch Oral Biol. 2009;54(1):3–17.
  • 5. Suckling GW. Developmental defects of enamel—historical and present-day perspectives of their pathogenesis. Adv Dent Res. 1989;3(2):87–94.
  • 6. Jacobsen PE, Henriksen TB, Haubek D, Østergaard JR. Developmental enamel defects in children prena-tally exposed to anti-epileptic drugs. PLoS One, 2013;8(3):e58213.
  • 7. Alaluusua S, Lukinmaa PL. Developmental dental toxicity of dioxin and related compounds—a re-view. Int Dent J. 2006;56(6):323-331.
  • 8. Alraddadi WH, Alsulami YF, Alsubhi AA, et al. What is the impact of stress on the development of molar incisor hypomineralization (MIH): a system-atic review. Saudi Dent J. 2025;37(4):17.
  • 9. Babajko S, Chaussain C, Jedeon K. Relations be-tween developmental dental defects and exposure to environmental toxicants exhibiting endocrine dis-rupting activity. In: Annales d'Endocrinologie, El-sevier Masson, 2025. p. 101765.
  • 10. Sezer B, Kaya R, Kodaman Dokumacıgil N, et al. Assessment of the oral health status of children with chronic kidney disease. Pediatr Nephrol. 2023;38:269–77.
  • 11. Laniado N, Cloidt M, Altonen B, Badner V. Interpro-fessional oral health collaboration: a survey of knowledge and practice behaviors of hospital-based primary care medical providers in New York city. Adv. medical educ. pract. 2021;1211-1218.
There are 11 citations in total.

Details

Primary Language English
Subjects Infant and Child Health
Journal Section Letter to Editor
Authors

Makbule Buse Dundar Sarı 0000-0002-8848-8850

Berkant Sezer 0000-0001-9731-6156

Submission Date December 15, 2025
Acceptance Date January 1, 2026
Publication Date January 6, 2026
Published in Issue Year 2026 Volume: 7 Issue: 1

Cite

APA Dundar Sarı, M. B., & Sezer, B. (2026). Developmental defects of enamel as a bridge between medicine and dentistry. Troia Medical Journal, 7(1), 57-59. https://doi.org/10.55665/troiamedj.1842475
AMA 1.Dundar Sarı MB, Sezer B. Developmental defects of enamel as a bridge between medicine and dentistry. Troia Med J. 2026;7(1):57-59. doi:10.55665/troiamedj.1842475
Chicago Dundar Sarı, Makbule Buse, and Berkant Sezer. 2026. “Developmental Defects of Enamel As a Bridge Between Medicine and Dentistry”. Troia Medical Journal 7 (1): 57-59. https://doi.org/10.55665/troiamedj.1842475.
EndNote Dundar Sarı MB, Sezer B (January 1, 2026) Developmental defects of enamel as a bridge between medicine and dentistry. Troia Medical Journal 7 1 57–59.
IEEE [1]M. B. Dundar Sarı and B. Sezer, “Developmental defects of enamel as a bridge between medicine and dentistry”, Troia Med J, vol. 7, no. 1, pp. 57–59, Jan. 2026, doi: 10.55665/troiamedj.1842475.
ISNAD Dundar Sarı, Makbule Buse - Sezer, Berkant. “Developmental Defects of Enamel As a Bridge Between Medicine and Dentistry”. Troia Medical Journal 7/1 (January 1, 2026): 57-59. https://doi.org/10.55665/troiamedj.1842475.
JAMA 1.Dundar Sarı MB, Sezer B. Developmental defects of enamel as a bridge between medicine and dentistry. Troia Med J. 2026;7:57–59.
MLA Dundar Sarı, Makbule Buse, and Berkant Sezer. “Developmental Defects of Enamel As a Bridge Between Medicine and Dentistry”. Troia Medical Journal, vol. 7, no. 1, Jan. 2026, pp. 57-59, doi:10.55665/troiamedj.1842475.
Vancouver 1.Dundar Sarı MB, Sezer B. Developmental defects of enamel as a bridge between medicine and dentistry. Troia Med J [Internet]. 2026 Jan. 1;7(1):57-9. Available from: https://izlik.org/JA84EP22EC