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Kronik sigara içiciliğinin EKG parametrelerine etkileri

Year 2022, Volume: 3 Issue: 2, 48 - 51, 31.05.2022
https://doi.org/10.55665/troiamedj.1100226

Abstract

Amaç: Mevcut çalışmada Tp-e/QT, Tp-e/QTc oranları ve Tp-e aralığı, kullanılarak kronik sigara içiciliğinin ventriküler repolarizasyon ve EKG parametreleri üzerine kronik etkisini araştırmayı amaçladık. Yöntem: Kesitsel tanımlayıcı desendeki çalışma hastane kayıtları üzerinden yürütülmüştür. Kronik sigara içen ve hiç sigara içmemiş 60’ar toplam 120 hasta çalışmaya alınmıştır. EKG’ler 25mm/sn kayıt hızı ile çekilmiştir. Tp-e aralığı, T dalgasının tepesinden sonuna kadarki süre, QT aralığı ise Q dalga başlangıcından T dalga sonuna kadar geçen süredir. EKG ölçümleri, ölçüm hatalarını azaltmak için iki araştırmacı tarafından büyüteç kullanılarak manuel olarak yapılmıştır. Ölçümlerde DII derivasyonu kullanılmıştır. Bulgular: Sigara içenlerde Tp-e/QT, Tp-e/QTc değerleri ve Tp-e aralığı daha yüksektir. Nabız, PR aralığı, QRS, QT, QTc, RV5, SV1 ve RV5+SV1 değerleri arasında anlamlı fark yoktur. Paket/yıl değeri, Tp-e aralığı, Tp-e/QT ve Tp-e/QTc değerlerinin her üçünü de etkileyen bir faktör olarak bulunmuştur. Sonuç: Sigara içenlerde Tp-e aralığı, Tp-e/QT ve Tp-e/QTc değerleri daha yüksektir. Ayrıca içilen sigara miktarı (paket/yıl) bu değerlerin artmasını sağlayan anlamlı bir faktör olduğu gösterilmiştir.

Supporting Institution

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Project Number

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References

  • 1. Walton K, Wang TW, Schauer GL, et al. State-specific prevalence of quit attempts among adult cigarette smokers - United States, 2011-2017. MMWR Morb Mortal Wkly Rep 2019;68(28):621-6.
  • 2. Heart Disease and Stroke, Smoking & Tobacco Use, CDC. https://www.cdc.gov/tobacco/basic_information/health_effects/heart_disease/index.htm. Accessed on Jan 10, 2022.
  • 3. Taşolar H, Balli M, Bayramoğlu A, et al. Effect of smoking on Tp-e interval, Tp-e/QT and Tp-e/QTc ratios as indices of ventricular arrhythmogenesis. Hear Lung Circ 2014;23(9):827-32.
  • 4. Ilgenli TF, Tokatli A, Akpinar O, Kiliçaslan F. The effects of cigarette smoking on the Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio. Adv Clin Exp Med 2015;24(6):973-8.
  • 5. D’Alessandro A, Boeckelmann I, Hammwhöner M, Goette A. Nicotine, cigarette smoking and cardiac arrhythmia: an overview. Eur J Prev Cardiol 2012;19(3):297-305.
  • 6. Gupta P, Patel C, Patel H, et al. T(p-e)/QT ratio as an index of arrhythmogenesis. J Electrocardiol 2008;41(6):567-74.
  • 7. Kors JA, RitsemavanEck HJ, vanHerpen G. The meaning of the Tp-Te interval and its diagnostic value. J Electrocardiol 2008;41(6):575-80.
  • 8. Erikssen G, Liestøl K, Gullestad L, Haugaa KH, Bendz B, Amlie JP. The terminal part of the QT interval (T peak to T end): a predictor of mortality after acute myocardial infarction. Ann Noninvasive Electrocardiol 2012;17(2):85-94.
  • 9. Smokerlyzer ® Range for use with piCO, piCO baby and Micro +, user manual. https://www.bedfont.com/documents/smokerlyzer-manual.pdf. Accessed on 17 Apr, 2021.
  • 10. Ulubay G, Dilektaşlı AG, Börekçi Ş, et al. Turkish Thoracic Society Consensus report: interpretation of spirometry. Turkish Thorac J 2019;20(1):69-89.
  • 11. Tanaka T, Yahagi K, Asami M, et al. Prognostic impact of electrocardiographic left ventricular hypertrophy following transcatheter aortic valve replacement. J Cardiol 2021;77(4):346-52.
  • 12. Ip M, Diamantakos E, Haptonstall K, et al. Tobacco and electronic cigarettes adversely impact ECG indexes of ventricular repolarization: implication for sudden death risk. Am J Physiol Heart Circ Physiol 2020;318(5):1176-84.
  • 13. Wang H, Shi H, Zhang L, et al. Nicotine is a potent blocker of the cardiac A-type K(+) channels. Effects on cloned Kv4.3 channels and native transient out ward current. Circulation 2000;102(10):1165-71.
  • 14. Yashima M, Ohara T, Cao JM, et al. Nicotine increases ventricular vulnerability to fibrillation in hearts with healed myocardial infarction. Am J Physiol Heart Circ Physiol 2000;278(6):2124-33.
  • 15. Mehta MC, Jain AC, Mehta A, Billie M. Cardiac arrhythmias following intravenous nicotine: experimental study in dogs. J Cardiovasc Pharmacol Ther 1997;2(4):291-8.
  • 16. Zareba KM, Truong VT, Mazur W, et al. T-wave and its association with myocardial fibrosis on cardiovascular magnetic resonance examination. Ann Noninvasive Electrocardiol 2021;26(2):e12819.
  • 17. Leone A. Biochemical markers of cardiovascular damage from tobacco smoke. Curr Pharm Des 2005;11(17):2199-208.
  • 18. Skipina TM, Upadhya B, Soliman EZ. Exposure to secondhand smoke is associated with increased left ventricular mass. Tob Induc Dis 2021;19:43.

Effects of chronic smoking on ECG parameters

Year 2022, Volume: 3 Issue: 2, 48 - 51, 31.05.2022
https://doi.org/10.55665/troiamedj.1100226

Abstract

Objectives: We aimed to investigate the effect of chronic smoking on ventricular repolarization and ECG parameters by using Tp-e/QT, Tp-e/QTc, and Tp-e intervals. Methods: This cross-sectional descriptive study was conducted on hospital registrations. A total of 120 patients, 60 of whom were chronic smokers and 60 were never smoked, were included in the study. ECGs were taken with a recording speed of 25 mm/sec. The Tp-e is the time from the peak of the T wave to the end of the T wave. The time from the beginning of the Q wave to the end of the T wave is the QT interval. ECG measurements were made manually by two researchers using a magnifying glass to reduce measurement errors. Measurements were made using the DII lead. Results: Tp-e/QT, Tp-e/QTc, and Tp-e were found to be higher in smokers than in non-smokers. There wasn’t difference between heart rate, PR interval, QRS, QT, QTc, RV5, SV1 and RV5+SV1 values. The package/year value was found to be a factor affecting all three of the Tp-e interval, Tp-e/QT and Tp-e/QTc values. Conclusion: Tp-e/QT, Tp-e/QTc values, and Tp-e interval were found to be higher in smokers than in non-smokers. The number of cigarettes smoked (pack/year) has been shown to be a significant factor that increases these values.

Project Number

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References

  • 1. Walton K, Wang TW, Schauer GL, et al. State-specific prevalence of quit attempts among adult cigarette smokers - United States, 2011-2017. MMWR Morb Mortal Wkly Rep 2019;68(28):621-6.
  • 2. Heart Disease and Stroke, Smoking & Tobacco Use, CDC. https://www.cdc.gov/tobacco/basic_information/health_effects/heart_disease/index.htm. Accessed on Jan 10, 2022.
  • 3. Taşolar H, Balli M, Bayramoğlu A, et al. Effect of smoking on Tp-e interval, Tp-e/QT and Tp-e/QTc ratios as indices of ventricular arrhythmogenesis. Hear Lung Circ 2014;23(9):827-32.
  • 4. Ilgenli TF, Tokatli A, Akpinar O, Kiliçaslan F. The effects of cigarette smoking on the Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio. Adv Clin Exp Med 2015;24(6):973-8.
  • 5. D’Alessandro A, Boeckelmann I, Hammwhöner M, Goette A. Nicotine, cigarette smoking and cardiac arrhythmia: an overview. Eur J Prev Cardiol 2012;19(3):297-305.
  • 6. Gupta P, Patel C, Patel H, et al. T(p-e)/QT ratio as an index of arrhythmogenesis. J Electrocardiol 2008;41(6):567-74.
  • 7. Kors JA, RitsemavanEck HJ, vanHerpen G. The meaning of the Tp-Te interval and its diagnostic value. J Electrocardiol 2008;41(6):575-80.
  • 8. Erikssen G, Liestøl K, Gullestad L, Haugaa KH, Bendz B, Amlie JP. The terminal part of the QT interval (T peak to T end): a predictor of mortality after acute myocardial infarction. Ann Noninvasive Electrocardiol 2012;17(2):85-94.
  • 9. Smokerlyzer ® Range for use with piCO, piCO baby and Micro +, user manual. https://www.bedfont.com/documents/smokerlyzer-manual.pdf. Accessed on 17 Apr, 2021.
  • 10. Ulubay G, Dilektaşlı AG, Börekçi Ş, et al. Turkish Thoracic Society Consensus report: interpretation of spirometry. Turkish Thorac J 2019;20(1):69-89.
  • 11. Tanaka T, Yahagi K, Asami M, et al. Prognostic impact of electrocardiographic left ventricular hypertrophy following transcatheter aortic valve replacement. J Cardiol 2021;77(4):346-52.
  • 12. Ip M, Diamantakos E, Haptonstall K, et al. Tobacco and electronic cigarettes adversely impact ECG indexes of ventricular repolarization: implication for sudden death risk. Am J Physiol Heart Circ Physiol 2020;318(5):1176-84.
  • 13. Wang H, Shi H, Zhang L, et al. Nicotine is a potent blocker of the cardiac A-type K(+) channels. Effects on cloned Kv4.3 channels and native transient out ward current. Circulation 2000;102(10):1165-71.
  • 14. Yashima M, Ohara T, Cao JM, et al. Nicotine increases ventricular vulnerability to fibrillation in hearts with healed myocardial infarction. Am J Physiol Heart Circ Physiol 2000;278(6):2124-33.
  • 15. Mehta MC, Jain AC, Mehta A, Billie M. Cardiac arrhythmias following intravenous nicotine: experimental study in dogs. J Cardiovasc Pharmacol Ther 1997;2(4):291-8.
  • 16. Zareba KM, Truong VT, Mazur W, et al. T-wave and its association with myocardial fibrosis on cardiovascular magnetic resonance examination. Ann Noninvasive Electrocardiol 2021;26(2):e12819.
  • 17. Leone A. Biochemical markers of cardiovascular damage from tobacco smoke. Curr Pharm Des 2005;11(17):2199-208.
  • 18. Skipina TM, Upadhya B, Soliman EZ. Exposure to secondhand smoke is associated with increased left ventricular mass. Tob Induc Dis 2021;19:43.
There are 18 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Articles
Authors

Muhammet Kızmaz 0000-0001-5408-3399

Funda Gökgöz Durmaz

Mehmet Emre Ay 0000-0001-6046-864X

Burcu Kumtepe Kurt 0000-0002-8897-7531

Ezgi Döner 0000-0003-2140-7347

Project Number yok
Publication Date May 31, 2022
Submission Date April 8, 2022
Published in Issue Year 2022 Volume: 3 Issue: 2

Cite

APA Kızmaz, M., Gökgöz Durmaz, F., Ay, M. E., Kumtepe Kurt, B., et al. (2022). Kronik sigara içiciliğinin EKG parametrelerine etkileri. Troia Medical Journal, 3(2), 48-51. https://doi.org/10.55665/troiamedj.1100226
AMA Kızmaz M, Gökgöz Durmaz F, Ay ME, Kumtepe Kurt B, Döner E. Kronik sigara içiciliğinin EKG parametrelerine etkileri. Troia Med J. May 2022;3(2):48-51. doi:10.55665/troiamedj.1100226
Chicago Kızmaz, Muhammet, Funda Gökgöz Durmaz, Mehmet Emre Ay, Burcu Kumtepe Kurt, and Ezgi Döner. “Kronik Sigara içiciliğinin EKG Parametrelerine Etkileri”. Troia Medical Journal 3, no. 2 (May 2022): 48-51. https://doi.org/10.55665/troiamedj.1100226.
EndNote Kızmaz M, Gökgöz Durmaz F, Ay ME, Kumtepe Kurt B, Döner E (May 1, 2022) Kronik sigara içiciliğinin EKG parametrelerine etkileri. Troia Medical Journal 3 2 48–51.
IEEE M. Kızmaz, F. Gökgöz Durmaz, M. E. Ay, B. Kumtepe Kurt, and E. Döner, “Kronik sigara içiciliğinin EKG parametrelerine etkileri”, Troia Med J, vol. 3, no. 2, pp. 48–51, 2022, doi: 10.55665/troiamedj.1100226.
ISNAD Kızmaz, Muhammet et al. “Kronik Sigara içiciliğinin EKG Parametrelerine Etkileri”. Troia Medical Journal 3/2 (May 2022), 48-51. https://doi.org/10.55665/troiamedj.1100226.
JAMA Kızmaz M, Gökgöz Durmaz F, Ay ME, Kumtepe Kurt B, Döner E. Kronik sigara içiciliğinin EKG parametrelerine etkileri. Troia Med J. 2022;3:48–51.
MLA Kızmaz, Muhammet et al. “Kronik Sigara içiciliğinin EKG Parametrelerine Etkileri”. Troia Medical Journal, vol. 3, no. 2, 2022, pp. 48-51, doi:10.55665/troiamedj.1100226.
Vancouver Kızmaz M, Gökgöz Durmaz F, Ay ME, Kumtepe Kurt B, Döner E. Kronik sigara içiciliğinin EKG parametrelerine etkileri. Troia Med J. 2022;3(2):48-51.