Atypical bullous reaction after PPD: A case report of tuberculous lymphadenitis

Year 2024, Volume: 5 Issue: 3, 112 - 114, 30.09.2024

Işıl Deniz Alıravcı , Cihan Yüksel

https://doi.org/10.55665/troiamedj.1427947

Abstract

The oldest and most commonly used tuberculosis screening test in the diagnosis of tuberculosis is the application in which a purified protein derivative (purified protein derivative = PPD) is injected into the skin. Hardening in the PPD treated area within 48-72 hours indicates delayed-type hypersensitivity reaction and infection with M. tuberculosis. In this article, a case who was injected with PPD and COVID-19 Biontech from the same arm on the same day and who developed an atypical bullous reaction at the ppd injection site is presented. It should be kept in mind that similar clinical findings may deve-lop in cases where PPD and COVID-19 vaccinations are applied to the same arm on the same day, and care should be taken to apply these two procedures at different times as much as possible.

Keywords

PPD, atypical bullous reaction, tuberculosıs, COVID-19 Vaccine

PPD sonrası gelişen atipik büllöz reaksiyon: Tüberküloz lenfadenit olgu sunumu

Abstract

Tüberkülozun tanısında en eski ve en sık kullanılan tüberküloz tarama testi, saflaştırılmış bir protein türevinin (pürifiye protein derivesi = PPD) deri içine enjekte edildiği uygulamadır. PPD uygulanan böl-gede 48-72 saat içinde sertleşme, gecikmiş tipte aşırı duyarlılık reaksiyonunu ve M. tuberculosis ile enfeksiyonu gösterir. Bu yazıda aynı gün içinde aynı koldan PPD ve COVID-19 Biontech aşılaması yapılan ve PPD enjeksiyon bölgesinde atipik büllöz reaksiyon gelişen bir olgu sunulmuştur. PPD ve COVID-19 aşılamalarının aynı gün aynı kola uygulandığı olgularda benzer klinik bulguların gelişebile-ceği akılda tutulmalı, bu iki işlemin mümkün olduğunca farklı zamanlarda uygulanmasına dikkat edilmelidir.

Keywords

PPD, atipik büllöz reaksiyon, tüberküloz, COVID-19 aşı

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