DÜŞÜK DERECELİ ENDOMETRİYAL STROMAL SARKOMLARDA LENF NODU METASTAZI VE REKÜRRENS

Abstract

Amaç: Bu retrospektif çalışmanın amacı, kliniğimizde opere edilmiş düşük dereceli endometrial stromal sarkom olgularında lenfatik yayılım deneyimimizi paylaşmak ve rekurrens şeklini araştırmaktır. Hastalar ve Yöntem: Kliniğimizde Ağustos 2001 ile Kasım 2011 arasında düşük dereceli endometriyal stromal sarkom nedeniyle opere edilmiş 14 olgu retrospektif olarak ele alındı. Yüm hastalara histerektomi yapıldı, ancak 6 hastaya pelvik ve/veya paraaortik lenfadenektomi yapıldı (% 43). Üç hasta takip sürecinden ayrıldı. Ortalama takip süresi 51 ay idi. Bulgular: 3 hastada lenfatik tutulum mevcuttu (%50). 11 takipli hastadan 2’sinde ekstrauterin tutulum saptandı (%18). İlk cerrahinin suboptimal olmasından dolayı, 3 hastada (%21) ikinci kez operasyona gereksinim oldu. Sonuç: Bu bulgular göstermektedir ki; düşük dereceli endometrial stromal sarkomlarda lenf nodu insidansı beklenenden daha fazladır. Daha geniş lenf nodu örneklemeleri veya daha fazla hastada lenfadenektomi sonuçları ile daha anlamlı sonuca varılabilir.

Keywords

• Endometriyal stromal sarkom, lenf nodu metastazı

LYMPH NODE METASTASES AND PATTERNS OF RECURRENCE IN LOW-GRADE ENDOMETRIAL STROMAL SARCOMA

Abstract

Objective: The purpose of this retrospective study is to investigate recurrence patterns and review our experience on lmyphatic dissemination in patients with low-grade endometrial stromal sarcoma. Study design: A retrospective review yielded 14 patients with ESS (all of them low-grade) who underwent primary surgical resection from August 2001 to November 2011. All patients underwent hysterectomy, whereas pelvic and/or paraaortic lymphadenectomy were performed in 6 patients (43%). Three of these patients had lack of follow-up. Median follow-up time was 51 months. Results: Lymphatic disease was noted in 3 patients (50%). Extrauterine recurrence was identified in 2 patients out of 11 full followup patients (18%). As the primary surgery was suboptimal, 3 patients (21%) were underwent secondary staging surgery. Conclusion: These findings suggest that the incidence of lymph node involvement in low-grade ESS is higher than expected. More extensive sampling of lymph nodes or complete lymphadenectomy in a larger number of patients may allow a better understanding of the frequency of lymph node involvement in low-grade ESS

Keywords

• Endometrial stromal sarcoma, lymph node metastases

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