SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI

H.öztürk Şahin; Beril Gürlek; Halit Arslan

SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI

Abstract

AMAÇ

Literatürdeki güncel gelişmeler ,normal sitolojide bulunan HPV(Human Papilloma Virus) tip 16 ve 18 dışındaki genotiplerde servikal intraepitelyal lezyon (SIL) görülme risk analizi çalışmalarına önem kazandırmıştır.Bizde çalışmamızda bu hasta grubunda yaptığımız kolposkopi eşliğindeki biopsi sonuçlarını inceledik.

GEREÇ VE YÖNTEM

Çalışmamıza , Mayıs 2016-2018 tarihleri arasında servikal sitolojisi normal olup,tekli yada çoklu HPV enfeksiyonu bulunmasına göre kategorize edilen 16 ve 18 dışı yüksek riskli HPV (hr-HPV)pozitifliği bulunan 104 hasta dahil edildi. Tüm hastalardan histolojik tanı için kolposkopi eşliğinde biopsi alındı.Sitolojik inceleme Bethesta metodu ile klasifiye edilirken,HPV DNA analizi Hybrid Capture 2 yöntemi ile yapıldı.

SONUÇLAR

104 hastamızın 59’unda (%56,7)displazi saptanmazken,33’ünde (%31,7) CIN1,12’sinde (%11,5) ≥CIN 2 saptandı.Çoklu HPV enfeksiyonunun SIL riskini arttırmadığı görüldü.≥CIN 2 saptanan 12 vakamızın 8’i(%66,6) HPV 31 genotipindeydi.

TARTIŞMA

HPV genotiplerinin risk skorlama çalışmaları,normal sitolojisi bulunan hastalarda doğrudan kolposkopiye refere edilecek hastaların triajını değiştirebilir.

Keywords

16/18 DIŞI HPV,NORMAL SİTOLOJİ,KOLPOSKOPİ

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Details

Primary Language

Turkish

Subjects

Surgery

Journal Section

Research Article

Authors

H.öztürk Şahin ^*
0000-0002-7915-8235
Türkiye

Beril Gürlek

Halit Arslan This is me

Publication Date

December 6, 2019

Submission Date

May 25, 2019

Acceptance Date

October 27, 2019

Published in Issue

Year 2018 Volume: 21 Number: 1

IZ

https://izlik.org/JA26LF49WW

Cite

RIS / Bibtex

APA

Şahin, H., Gürlek, B., & Arslan, H. (2019). SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI. Türk Jinekolojik Onkoloji Dergisi, 21(1), 6-9. https://izlik.org/JA26LF49WW

AMA

1.Şahin H, Gürlek B, Arslan H. SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI. Türk Jinekolojik Onkoloji Dergisi. 2019;21(1):6-9. https://izlik.org/JA26LF49WW

Chicago

Şahin, H.öztürk, Beril Gürlek, and Halit Arslan. 2019. “SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI”. Türk Jinekolojik Onkoloji Dergisi 21 (1): 6-9. https://izlik.org/JA26LF49WW.

EndNote

Şahin H, Gürlek B, Arslan H (December 1, 2019) SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI. Türk Jinekolojik Onkoloji Dergisi 21 1 6–9.

IEEE

[1]H. Şahin, B. Gürlek, and H. Arslan, “SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI”, Türk Jinekolojik Onkoloji Dergisi, vol. 21, no. 1, pp. 6–9, Dec. 2019, [Online]. Available: https://izlik.org/JA26LF49WW

ISNAD

Şahin, H.öztürk - Gürlek, Beril - Arslan, Halit. “SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI”. Türk Jinekolojik Onkoloji Dergisi 21/1 (December 1, 2019): 6-9. https://izlik.org/JA26LF49WW.

JAMA

1.Şahin H, Gürlek B, Arslan H. SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI. Türk Jinekolojik Onkoloji Dergisi. 2019;21:6–9.

MLA

Şahin, H.öztürk, et al. “SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI”. Türk Jinekolojik Onkoloji Dergisi, vol. 21, no. 1, Dec. 2019, pp. 6-9, https://izlik.org/JA26LF49WW.

Vancouver

1.H.öztürk Şahin, Beril Gürlek, Halit Arslan. SERVİKAL SİTOLOJİSİ NORMAL OLUP,HPV 16 VE 18 GENOTİPİ DIŞI HPV ENFEKSİYONU BULUNAN HASTALARDAKİ KOLPOSKOPİ SONUÇLARI. Türk Jinekolojik Onkoloji Dergisi [Internet]. 2019 Dec. 1;21(1):6-9. Available from: https://izlik.org/JA26LF49WW