Review

Rotem Guided Bleeding Management

Volume: 4 Number: 1 April 21, 2025
EN TR

Rotem Guided Bleeding Management

Abstract

Rotational thromboelastometry (ROTEM) enables the assessment of viscoelastic profiles of whole blood in a variety of clinical settings. ROTEM-guided bleeding management has become an essential part of patient blood management (PBM). ROTEM-guided PBM (Patient Blood Management) has been shown to be effective in reducing bleeding, transfusion requirements, complication rates, and healthcare costs. Several randomized controlled trials and meta-analyses have provided evidence that ROTEM guidance improves perioperative morbidity and mortality in bleeding patients. ROTEM results and the corresponding hemostatic interventions for common bleeding scenarios are discussed.

Keywords

References

  1. 1. Zacharowski K, Spahn DR. Patient blood management equals patient safety. Best Pract Res Clin Anaesthesiol. 2016;30(2):159-169. doi:10.1016/j.bpa.2016.04.008
  2. 2. Inaba K, Branco BC, Rhee P, et al. Impact of plasma transfusion in trauma patients who do not require massive transfusion. J Am Coll Surg. 2010;210(6):957-965. doi:10.1016/j.jamcollsurg.2010.01.031
  3. 3. Desborough M, Sandu R, Brunskill SJ, et al. Fresh frozen plasma for cardiovascular surgery. Cochrane Database Syst Rev. 2015;2015(7):Cd007614. doi:10.1002/14651858.CD007614.pub2
  4. 4. Warner MA, Chandran A, Jenkins G, Kor DJ. Prophylactic Plasma Transfusion Is Not Associated With Decreased Red Blood Cell Requirements in Critically Ill Patients. Anesth Analg. 2017;124(5):1636-1643. doi:10.1213/ane.0000000000001730
  5. 5. Warner MA, Jia Q, Clifford L, et al. Preoperative platelet transfusions and perioperative red blood cell requirements in patients with thrombocytopenia undergoing noncardiac surgery. Transfusion. 2016;56(3):682-690. doi:10.1111/trf.13414
  6. 6. Khan S, Brohi K, Chana M, et al. Hemostatic resuscitation is neither hemostatic nor resuscitative in trauma hemorrhage. J Trauma Acute Care Surg. 2014;76(3):561-567; discussion 567-568. doi:10.1097/ta.0000000000000146
  7. 7. Khan S, Davenport R, Raza I, et al. Damage control resuscitation using blood component therapy in standard doses has a limited effect on coagulopathy during trauma hemorrhage. Intensive Care Med. 2015;41(2):239-247. doi:10.1007/s00134-014-3584-1
  8. 8. Holcomb JB, Tilley BC, Baraniuk S, et al. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA. 2015;313(5):471-482. doi:10.1001/jama.2015.12

Details

Primary Language

English

Subjects

General Surgery

Journal Section

Review

Early Pub Date

April 8, 2025

Publication Date

April 21, 2025

Submission Date

November 15, 2024

Acceptance Date

February 8, 2025

Published in Issue

Year 2025 Volume: 4 Number: 1

AMA
1.Yılmaz MA, Özgödek HB, Uzun N, Aydın ME, Çelik EC. Rotem Guided Bleeding Management. Trends in Surgical Sciences. 2025;4(1):44-50. doi:10.61745/tss.1671472

Content of this journal is licensed under a Creative Commons Attribution NonCommercial 4.0 International License

33719