Evaluation of Factors Affecting Health-Related Quality of Life in Patients with Diabetic Retinopathy

Year 2022, Volume: 6 Issue: 3, 230 - 240, 29.12.2022

Ahmet Sakallıoğlu , İrfan Akaray , Sultan Kaya , Özlem Kaya , Gizem Köse , Rüveyde Garip , Hande Guclu

https://doi.org/10.25048/tudod.1127641

Abstract

Aim: To investigate the factors affecting health-related quality of life (HRQOL) in diabetic retinopathy (DRP) patients.
Material and Methods: The study included 800 eyes of 400 type 2 diabetes patients who were followed up for DRP. After the ophthalmologic examination, the patients completed the Short Form-36 (SF-36) questionnaire. According to SF-36, summary measures of physical function, physical role, body pain, general health, vitality, social functionality, emotional role, and mental health, physical and mental components were calculated. Demographic characteristics of the patients were noted from the patient files. To compare two independent groups, the independent sample T-test was used when normal distribution was assumed, and the Mann-Whitney U test was used when the normality of the data was rejected. In the comparison of more than two independent groups, Bonferroni or Tamhane’s T2 corrected ANOVA test was used and the relationship between numerical variables was evaluated with the Pearson correlation test. The significance level was accepted as p<0.05.
Results: HRQOL was low in females (p<0.001) and patients with diabetes more than 15 years (p=0.002 for body pain; p<0.001 for others). Physical and mental component summary measurement values were lower in older patients (p=0.046, p=0.034, respectively). In patients who underwent pan-retinal photocoagulation (PRFC) and were diagnosed with ischemia; except body pain (for PRFC p=0.178;for ischemia p=0.252), HRQoL values were found to be significantly lower (p<0.05). From proliferative diabetic retinopathy (PDR) patients to DRP(-) patients, except for body pain, HRQ was significantly increased (p<0.05). All subgroup values were low in patients with visual acuity less than 20/40, except mental health (p=0.335) and body pain (p=0.069).
Conclusion: Considering that in patients who are female, have a history of DM for 15 years or more, are partially older; patients with more PRFC, patients with retinal ischemia, and have a lower vision, the HRQOL may be low; so this may prompt us to be more careful in the treatment management of these patients

Keywords

Diabetic retinopathy, Diabetes Mellitus, Quality of Life.

Diyabetik Retinopatili Hastalarda Sağlıkla İlişkili Yaşam Kalitesini Etkileyen Faktörlerin Değerlendirilmesi

Abstract

Amaç: Diyabetik retinopati (DRP) hastalarında sağlıkla ilişkili yaşam kalitesini (SİYK) etkileyen faktörlerin araştırılması.
Gereç ve Yöntemler: Çalışmaya tip 2 diyabet nedeniyle DRP açısından takipli 400 hastanın 800 gözü katılmıştır. Hastalar oftalmolojik muayene sonrasında Kısa Form-36 (SF-36) anketini doldurmuştur. SF-36’ya göre fiziksel işlev, fiziksel rol, bedensel ağrı, genel sağlık, canlılık, sosyal işlevsellik, duygusal rol ve ruh sağlığı, fiziksel ve zihinsel bileşen özet ölçümleri hesaplandı. Hastaların demografik özellikleri hasta dosyalarından not edilmiştir. İki bağımsız grubu karşılaştırmak için normal dağılım varsayıldığında bağımsız örneklemlerde T-testi, verilerin normalliği reddedildiğinde Mann-Whitney U testi kullanıldı. İkiden fazla olan bağımsız grupların karşılaştırılmasında Bonferroni veya Tamhane’s T2 düzeltmeli ANOVA testi, sayısal değişkenler arasındaki ilişki Pearson korelasyon testi ile değerlendirildi. Anlamlılık düzeyi p<0,05 olarak kabul edildi.
Bulgular: Kadınların (p<0,001), diyabet süresi 15 yıldan fazla olanların (bedensel ağrı için p=0,002; diğerleri için p<0,001) SİYK düşük saptandı. Fiziksel ve zihinsel bileşen özet ölçüm değerleri 65 yaşından büyük hastalarda düşüktü (sırasıyla p=0,046, p=0,034). Panretinal fotokogülasyon (PRFK) yapılan ve iskemi saptanan hastalarda SİYK değerleri bedensel ağrı hariç (PRFK için p=0,178; iskemi için p=0,252) anlamlı düşük saptandı (p<0,05). Proliferatif diyabetik retinopati (PDR) hastalarından DRP(-) hastalara doğru SİYK bedensel ağrı hariç anlamlı şekilde yükseldi (p<0,05). Görme keskinliği 20/40’tan az olan hastalarda ruh sağlığı (p=0,335) ve bedensel ağrı (p=0,069) hariç tüm alt grup değerleri düşüktü.
Sonuç: Kadın cinsiyetin, 15 yıl ve üzerinde diyabet öyküsünün, kısmen ileri yaşın, daha fazla PRFK yapılmış olan hastaların, retinal iskemisi olan hastaların ve daha düşük görme düzeyine sahip hastaların SİYK’sının düşük olabileceği göz önünde bulundurulması, bu hastaların tedavi yönetiminde daha dikkatli olmamızı sağlayabilir

Keywords

Diyabetik retinopati, Diyabet, Yaşam kalitesi

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