EVALUATION OF COGNITIVE NEUROSCIENCE STATE AND OXIDATIVE STRESS AND BLOOD FACTORS IN CEMENT FACTORY WORKERS
Abstract
Cement factories are regarded as pollutant industries due to high dust
production. Cement factory workers are seriously exposed to pollution through
skin absorption, inhalation and ingestion of the dust. Cement dusts are
contained of several molecules that are participated in free radicals over
production and various illness pathogenesis. Therefore, the present study aimed
to assess the oxidative stress, blood factors and cognitive neuroscience state
among cement factory workers.
The present study conducted as a cross-sectional study with a control
group. The research sample was included of 41 workers exposed to cement factory
dust and 41 well-matched subjects with no history of occupational cement
exposure as control group. In order to assess oxidative stress indicators, the
biochemical factors, lipid peroxidation and total antioxidants of blood serum
sample of subjects were analyzed. Moreover to assess psychiatric disorders, a
cognitive neurological questionnaire was used which consisted of 74 questions
to measure cognitive functions, psychomotor speed, selective attention, verbal,
non-verbal and prospective memory, visual and spatial functions, and
initiative/ energy levels.
The results indicated, lipid peroxidation and antioxidant activity
revealed no significant differences between cement factory workers and control
group. Additionally, triglycerides and alanine amino transferase decreased
significantly while alkaline phosphatase represented a significant increase in
workers. However, the non-verbal memory impairment subscale was significantly
higher in workers in compare to control group.
The results suggested that cement dust exposure might induce adverse
effects on the biochemical parameters and could be associated with risk of
oxidative stress and neurocognitive disorders.
The results showed that workers exposed to cement dust were at the risk
of oxidative stress and blood and liver abnormalities.
References
- Department of Biology, Payame Noor University, Tehran, Iran
- Department of physical therapy, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
- Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, Tehran University of Medical Science, Tehran, Iran
Abstract
References
- Department of Biology, Payame Noor University, Tehran, Iran
- Department of physical therapy, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
- Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, Tehran University of Medical Science, Tehran, Iran
Details
| Journal Section | Articles |
|---|---|
| Authors | |
| Publication Date | February 16, 2017 |
| Published in Issue | Year 2017 Volume: Volume 2 Issue: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology |
