THE RELATIONSHIP BETWEEN OXIDATIVE STRESS AND COGNITIVE NEUROPSYCHOLOGICAL STATE DUE TO ELECTROMAGNETIC FIELDS IN POWER PLANT WORKERS

Year 2017, Volume: Volume 2 Issue: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 69 - 69, 16.02.2017

Ali Akbar Malekırad Tahereh Sadeghı Asma Bahranıfard Samira Shahrjerdı Kobra Rahzanı Mohammad Abdollahı

Abstract

Oxidative stress
due to EMFs may be a main contributing factor in metabolic reactions. The
present study aimed to evaluate the effect of EMFs on oxidative stress and
cognitive neuropsychological disorders in power plant workers in comparison
with controls and determine the relationship between them.

This study
designed as a cross-sectional study with a control group. The research sample
was included 66 steel power plant workers who were exposed to EMFs more than
five years and 35 well-matched workers with no EMFs exposure. The assessment
was carried out by measuring serum level of biochemical parameters such as FBS
(fasting blood sugar), triglyceride, cholesterol, HDL (high- density
lipoprotein), LDL (low-density lipoprotein), AST (aspartate aminotransferase),
ALT (alanine aminotransferase), and DNA damage. Additionally, all participants
were assessed by cognitive neuropsychological and psychosocial questionnaires
(SNI, SCL90). All data were analyzed by T-test, Multivariate analysis of variance
and Mann–Whitney U test and Pearson’s correlation coefficient.

The results
revealed that FBS level among workers was significantly lower in comparison to
control group. Additionally, AST and HDL were significantly higher in workers.
According to cognitive subscales, non verbal memory, attention and executive
functions were significantly lower in EMFs-exposed subjects. Moreover, the
psychological subscales; somatization obsessive-compulsive, interpersonal
sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation,
and psychoticism were significantly increased in the exposed. There was a
converse relationship between DNA damage and OBS, DEP, PAR and PSY and Positive
Symptoms Total.

The EMFs
exposure could reflect the oxidative stress increment resulting in a decrease
in blood glucose level and the liver function markers. Furthermore, the
neurocognitive parameters are influenced by EMFs that could be a consequence of
oxidative stress in central nervous system.  
Also, DNA damage and marked neuropsychological disorders were evident in
the workers. Hence it is necessary to consider the precise effect of EMFs on
all living organisms in order to provide safety condition in the workplaces.

Keywords

THE RELATIONSHIP BETWEEN OXIDATIVE STRESS AND COGNITIVE NEUROPSYCHOLOGICAL STATE DUE TO ELECTROMAGNETIC FIELDS IN POWER PLANT WORKERS

References

• Ali Akbar MALEKIRAD, Tahereh SADEGHI, Asma BAHRANIFARD, Samira SHAHRJERDI, Kobra RAHZANI, Mohammad ABDOLLAHI
• Department of Biology, Payame Noor University, Tehran, Iran Department of physical therapy, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran Faculty of Nursing and Midwifery, Arak University of Medical Science, Arak, Iran Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, Tehran University of Medical Science