Abstract
A measurement
result is complete only when accompanied by a quantitative statement of its
uncertainty. The uncertainty is required in order to decide if the result is
adequate for its intended purpose and to ascertain if it is consistent with
other similar results. The aim of this
study is to calculate measurement uncertainty of digoxin parameter by using
internal and external quality control data and to compare these calculated
measurement uncertainties with CLIA and RILIBAK’s total error % (TEa%) value.
In the
calculation of measurement uncertainty, six step “uncertainty calculation
model, that is defined in Nordest guide which is based on European Accreditation
Guideline / 12 /. European Tecnical Report: 1 / 3 and ISO / DTS 21748 Guideline
/8/ was used. Last six months internal and external datas were used for
calculations.
TEa % values for
Digoxin was 9,33. This value was not higher than TEa % value of RILIBAK
(TEa%30) and CLIA (TEa%20).
Drug analysis
are important for follow-up of patients so their correct measurements are
critical. However as far as our knowledge measurement uncertainity of drugs
were not common
Laboratories
should use same guideline for standardization of measurement uncertainty and
gave results lower than TEa% thats measurement uncertainty is calculated
according to the same guideline. Moreover, labratories should report patient’s
result with the measurement uncertainty values to clinicians.
References
- P. BARAN, C. BAL, S. TURHAN, O. ŞEN , O. EREL
- Ankara Ataturk Education and Research Hospital, Clinical Biochemistry, Ankara, Turkey
Abstract
References
- P. BARAN, C. BAL, S. TURHAN, O. ŞEN , O. EREL
- Ankara Ataturk Education and Research Hospital, Clinical Biochemistry, Ankara, Turkey
Details
| Journal Section | Articles |
|---|---|
| Authors | |
| Publication Date | February 16, 2017 |
| Published in Issue | Year 2017 Volume: Volume 2 Issue: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology |
