Derleme
BibTex RIS Kaynak Göster

Diş Hekimliğinde Enjekte Edilebilir Kemik Greftlerinin Kullanımı

Yıl 2024, Cilt: 3 Sayı: 3, 452 - 458, 27.12.2024
https://doi.org/10.58711/turkishjdentres.vi.1471220

Öz

Dental uygulamalarda kullanılan biyomateryaller, geçmişten günümüze değişim ve gelişim sürecindedir. Klinik pratiğinde tedavi başarı oranındaki yükseliş, hasta konforunda artış ve maliyetin düşürülüp tedavinin ulaşılabilirliğinin artırılması temel motivasyon kaynaklarından olmuştur. Greft materyallerinde çeşitli sınırlamaların varlığı sebebiyle, alternatif veya yardımcı yeni materyallerin geliştirilmesi
ihtiyacı ortaya çıkmıştır. Enjekte edilebilir formdaki kemik greftleri klinisyene uygulama kolaylığı sağlamasının yanı sıra, ihtiva ettiği moleküllerle kemik rejenerasyon sürecinde iyileşme sağlamaktadır. Yapılan preklinik ve klinik çalışmalarla kemik iyileşmesine katkısı halen incelenmekte olup; belirgin avantajlarının yanında uygulamada kısıtlı kalması, gelişim sürecinin devam ettiğini göstermektedir.
Yayınlanan klinik çalışmalarda biyomateryalin tedavi protokolü değerlendirilmiş, biyolojik süreci takip edilmiştir. Bu derlemenin amacı, kaydedilen bu verileri sunmak ve enjekte edilebilir kemik greflerinin klinik uygulamalardaki başarıları hakkında kapsamlı bilgi sağlamaktır.

Kaynakça

  • 1. Greenwald AS, Boden SD, Goldberg VM, Khan Y, Laurencin CT, Rosier RN. Bone-graft substitutes: facts, fictions, and applications. J Bone Joint Surg Am. 2001;83(2):98-103.
  • 2. Szpalski M, Gunzburg R. Applications of calcium phosphate based cancellous bone void fillers in trauma surgery. Orthopedics. 2002;25(5):601-9.
  • 3. Tuz HH, Akal UK, Cambazoğlu M, Kişnişç i RS. Use of spongious bone chips and fascia temporalis in alveolar bone defects. Turk Jou Med Sci. 2004;34(3):179-185.
  • 4. Den Boer FC, Wipperman BW, Blokhuis TJ, Patka P, Bakker FC, Haarman HJ. Healing of segmental bone defects with granular porous hydroxyapatite augmented with recombinant human osteogenic protein-1 or otologous bone marrow. J Orthopaedics Res. 2003;21(3):521-528.
  • 5. Gigante A, Capella M, Manzotti S, Cecconi S, Greco F, Di Primio R, Mattioli-Belmonte M. Osteoinduction properties different growth factors on cells from non-union patients: In vitro study for clinical application. J Biol Regul Homeost Agents. 2010;24(1):51-62.
  • 6. Szpalski M, Gunzburg R. rhBMP-2: A novel osteoinductive alternative to autogenous bone graft? Acta Orthop Belg. 2005;71(2):33-48.
  • 7. Kirschner RE, Karmacharya J, Ong G. Synthetic hybrid grafts for craniofacial reconstruction: Sustained gene delivery using a calcium phosphate bone mineral substitute. Ann Plast Surg. 2001;46(5):538-45
  • 8. Kökden A, Türker M. Oral ve maksillofasiyal cerrahide kullanılan kemik greftleri ve biyomateryaller. Cumhuriyet Üni. Diş Hekimliği Fakültesi Dergisi. 1999;2:134-140.
  • 9. Cypher TJ, Grossman JP. Biological principles of bone graft healing. J Foot Ankle Surg. 1996;35(5):413–7.
  • 10. Rosen PS, Reynolds MA, Bowers GM. The treatment of intrabony defects with bone grafts. Periodontol 2000. 2000;22:88-103.
  • 11. Younger EM, Chapman MW. Morbidity at bone graft donor sites. J Orthop Trauma. 1989;3(3):192–5.
  • 12. Al Ruhaimi KA. Bone graft substitutes: a comparative qualitative histologic review of current osteoconductive grafting materials. Int J Oral Maxillofac Implants. 2001;16(1):105–14.
  • 13. Cheng EY, Gebhardt MC. Allograft reconstructions of the shoulder after bone tumor resections. Orthop Clin North Am. 1991;22(1):37-48.
  • 14. Piattelli M, Favero GA, Scarano A, Orsini G, Piattelli A. Bone reactions to anorganic bovine bone (Bio-Oss) used in sinusmentation procedures: A histologic long-term report of 20 cases in humans. Int J Oral Maxillofac Implants. 1999;14(6):835-840.
  • 15. Wenz B, Oesch B, Horst M. Analysis of the risk of transmitting bovine spongiform encephalopathy through bone grafts derived from bovine bone. Biomaterials. 2001;22(12):1599–606.
  • 16. Festa VM, Addabbo F, Laino L, Femiano F, Rullo R. Porcine‐derived xenograft combined with a soft cortical membrane versus extraction alone for implant site development: a clinical study in humans. Clin Implant Dent Relat Res. 2013;15(5):707–13.
  • 17. Sheikh Z, Najeeb S, Khurshid Z, Verma V, Rashid H, Glogauer M. Biodegradable materials for bone repair and tissue engineering applications. Materials. 2015;8(9):5744– 5794.
  • 18. Tamimi F, Sheikh Z, Barralet J. Dicalcium phosphate cements: brushite and monetite. Acta Biomater. 2012;8(2):474–87.
  • 19. Moussi H, Weiss P, Bideau J, Gautier H, Charbonnier B. Injectable macromolecule-based calcium phosphate bone substitutes. Materials Advances. 2022;3:6125–6141.
  • 20. Wolff KD, Swaid S, Nolte D, Böckmann RA, Hölzle F, Müller-Mai C. Degradable injectable bone cement in maxillofacial surgery: Indications and clinical experience in 27 patients. J Craniomaxillofac Surg. 2004;32(2):71-9.
  • 21. Stanton DC, Chou JC, Carrasco LR. Injectable calciumphosphate bone cement (Norian) for reconstruction of a large mandibular defect: A case report. J Oral Maxillofac Surg. 2004;62(2):235-40.
  • 22. Weiss P, Layrolle P, Clergeau LP, Enckel B, Pilet P, Amouriq Y, Daculsi G, Giumelli B. The safety and efficacy of an injectable bone substitute in dental sockets demonstrated in a human clinical trial. Biomaterials. 2007;28(22):3295– 305.
  • 23. Irinakis T. Efficacy of injectable demineralized bone matrix as graft material during sinus elevation surgery with simultaneous implant placement in the posterior maxilla: clinical evaluation of 49 sinuses. J Oral Maxillofac Surg. 2011;69(1):134-41.
  • 24. Papanchev G, Georgiev T, Peev S, Arnautska H, Zgurova N, Borisova-Papancheva T, Dzhongova E. Comparison of the rates of bone regeneration in Sinus lift grafting with a Calcium-Phosphate paste between the 6th and the 9th month - A clinical case. Scripta Scientifica Medicinae Dentalis. 2015;1:41.
  • 25. Georgiev T, Peev S, Arnautska H, Gencheva A, Gerdzhikov I. An evaluation of three-dimensional scans of the timedependent volume changes in bone grafting materials. Int J Sci Res. 2017;6(1):562–571.
  • 26. Lorenz J, Barbeck M, Kirkpatrick C, Sader R, Lerner H, Ghanaati S. Injectable Bone Substitute Material on the Basis of β-TCP and Hyaluronan Achieves Complete Bone Regeneration While Undergoing Nearly Complete Degradation. Int J Oral Maxillofac Implants. 2018;33(3):636–644.
  • 27. Čandrlić M, Perić Kačarević Ž, Ivanišević Z, Tomas M, Včev A, Faj D, Matijević M. Histological and Radiological Features of a Four-Phase Injectable Synthetic Bone Graft in Guided Bone Regeneration: A Case Report. Int J Environ Res Public Health. 2020;18(1):206
  • 28. Čandrlić M, Tomas M, Karl M, Malešić L, Včev A, Perić Kačarević Ž, Matijević M. Comparison of Injectable Biphasic Calcium Phosphate and a Bovine Xenograft in Socket Preservation: Qualitative and Quantitative Histologic Study in Humans. Int J Mol Sci. 2022;23(5):2539.

Injectable Bone Substitutes in Dentistry

Yıl 2024, Cilt: 3 Sayı: 3, 452 - 458, 27.12.2024
https://doi.org/10.58711/turkishjdentres.vi.1471220

Öz

Biomaterials for dental applications are in a change and devolopment process from past to future. In clinical practice, improving treatment success rates, to enhance patient comfort and improve access to treatment with low costs is the main motivation sources. Due to the presence of various limitations
in bone substitutes, have revealed the need to develop alternative or auxiliary new materials. Bone grafts in injectable form not only provide easy application to the clinician, but also provide improvement in the bone regeneration process with the molecules they contain. Its contribution to bone healing
is still being examined with preclinical and clinical research. Despite obvious benefits, limitation in clinical use shows us that the development process continues. In published clinical studies, the treatment protocol of the biomaterial was evaluated and its biological process was followed. The aim of this review
is to present these recorded data and provide comprehensive information about the success of injectable bone substitutes in clinical applications.

Kaynakça

  • 1. Greenwald AS, Boden SD, Goldberg VM, Khan Y, Laurencin CT, Rosier RN. Bone-graft substitutes: facts, fictions, and applications. J Bone Joint Surg Am. 2001;83(2):98-103.
  • 2. Szpalski M, Gunzburg R. Applications of calcium phosphate based cancellous bone void fillers in trauma surgery. Orthopedics. 2002;25(5):601-9.
  • 3. Tuz HH, Akal UK, Cambazoğlu M, Kişnişç i RS. Use of spongious bone chips and fascia temporalis in alveolar bone defects. Turk Jou Med Sci. 2004;34(3):179-185.
  • 4. Den Boer FC, Wipperman BW, Blokhuis TJ, Patka P, Bakker FC, Haarman HJ. Healing of segmental bone defects with granular porous hydroxyapatite augmented with recombinant human osteogenic protein-1 or otologous bone marrow. J Orthopaedics Res. 2003;21(3):521-528.
  • 5. Gigante A, Capella M, Manzotti S, Cecconi S, Greco F, Di Primio R, Mattioli-Belmonte M. Osteoinduction properties different growth factors on cells from non-union patients: In vitro study for clinical application. J Biol Regul Homeost Agents. 2010;24(1):51-62.
  • 6. Szpalski M, Gunzburg R. rhBMP-2: A novel osteoinductive alternative to autogenous bone graft? Acta Orthop Belg. 2005;71(2):33-48.
  • 7. Kirschner RE, Karmacharya J, Ong G. Synthetic hybrid grafts for craniofacial reconstruction: Sustained gene delivery using a calcium phosphate bone mineral substitute. Ann Plast Surg. 2001;46(5):538-45
  • 8. Kökden A, Türker M. Oral ve maksillofasiyal cerrahide kullanılan kemik greftleri ve biyomateryaller. Cumhuriyet Üni. Diş Hekimliği Fakültesi Dergisi. 1999;2:134-140.
  • 9. Cypher TJ, Grossman JP. Biological principles of bone graft healing. J Foot Ankle Surg. 1996;35(5):413–7.
  • 10. Rosen PS, Reynolds MA, Bowers GM. The treatment of intrabony defects with bone grafts. Periodontol 2000. 2000;22:88-103.
  • 11. Younger EM, Chapman MW. Morbidity at bone graft donor sites. J Orthop Trauma. 1989;3(3):192–5.
  • 12. Al Ruhaimi KA. Bone graft substitutes: a comparative qualitative histologic review of current osteoconductive grafting materials. Int J Oral Maxillofac Implants. 2001;16(1):105–14.
  • 13. Cheng EY, Gebhardt MC. Allograft reconstructions of the shoulder after bone tumor resections. Orthop Clin North Am. 1991;22(1):37-48.
  • 14. Piattelli M, Favero GA, Scarano A, Orsini G, Piattelli A. Bone reactions to anorganic bovine bone (Bio-Oss) used in sinusmentation procedures: A histologic long-term report of 20 cases in humans. Int J Oral Maxillofac Implants. 1999;14(6):835-840.
  • 15. Wenz B, Oesch B, Horst M. Analysis of the risk of transmitting bovine spongiform encephalopathy through bone grafts derived from bovine bone. Biomaterials. 2001;22(12):1599–606.
  • 16. Festa VM, Addabbo F, Laino L, Femiano F, Rullo R. Porcine‐derived xenograft combined with a soft cortical membrane versus extraction alone for implant site development: a clinical study in humans. Clin Implant Dent Relat Res. 2013;15(5):707–13.
  • 17. Sheikh Z, Najeeb S, Khurshid Z, Verma V, Rashid H, Glogauer M. Biodegradable materials for bone repair and tissue engineering applications. Materials. 2015;8(9):5744– 5794.
  • 18. Tamimi F, Sheikh Z, Barralet J. Dicalcium phosphate cements: brushite and monetite. Acta Biomater. 2012;8(2):474–87.
  • 19. Moussi H, Weiss P, Bideau J, Gautier H, Charbonnier B. Injectable macromolecule-based calcium phosphate bone substitutes. Materials Advances. 2022;3:6125–6141.
  • 20. Wolff KD, Swaid S, Nolte D, Böckmann RA, Hölzle F, Müller-Mai C. Degradable injectable bone cement in maxillofacial surgery: Indications and clinical experience in 27 patients. J Craniomaxillofac Surg. 2004;32(2):71-9.
  • 21. Stanton DC, Chou JC, Carrasco LR. Injectable calciumphosphate bone cement (Norian) for reconstruction of a large mandibular defect: A case report. J Oral Maxillofac Surg. 2004;62(2):235-40.
  • 22. Weiss P, Layrolle P, Clergeau LP, Enckel B, Pilet P, Amouriq Y, Daculsi G, Giumelli B. The safety and efficacy of an injectable bone substitute in dental sockets demonstrated in a human clinical trial. Biomaterials. 2007;28(22):3295– 305.
  • 23. Irinakis T. Efficacy of injectable demineralized bone matrix as graft material during sinus elevation surgery with simultaneous implant placement in the posterior maxilla: clinical evaluation of 49 sinuses. J Oral Maxillofac Surg. 2011;69(1):134-41.
  • 24. Papanchev G, Georgiev T, Peev S, Arnautska H, Zgurova N, Borisova-Papancheva T, Dzhongova E. Comparison of the rates of bone regeneration in Sinus lift grafting with a Calcium-Phosphate paste between the 6th and the 9th month - A clinical case. Scripta Scientifica Medicinae Dentalis. 2015;1:41.
  • 25. Georgiev T, Peev S, Arnautska H, Gencheva A, Gerdzhikov I. An evaluation of three-dimensional scans of the timedependent volume changes in bone grafting materials. Int J Sci Res. 2017;6(1):562–571.
  • 26. Lorenz J, Barbeck M, Kirkpatrick C, Sader R, Lerner H, Ghanaati S. Injectable Bone Substitute Material on the Basis of β-TCP and Hyaluronan Achieves Complete Bone Regeneration While Undergoing Nearly Complete Degradation. Int J Oral Maxillofac Implants. 2018;33(3):636–644.
  • 27. Čandrlić M, Perić Kačarević Ž, Ivanišević Z, Tomas M, Včev A, Faj D, Matijević M. Histological and Radiological Features of a Four-Phase Injectable Synthetic Bone Graft in Guided Bone Regeneration: A Case Report. Int J Environ Res Public Health. 2020;18(1):206
  • 28. Čandrlić M, Tomas M, Karl M, Malešić L, Včev A, Perić Kačarević Ž, Matijević M. Comparison of Injectable Biphasic Calcium Phosphate and a Bovine Xenograft in Socket Preservation: Qualitative and Quantitative Histologic Study in Humans. Int J Mol Sci. 2022;23(5):2539.
Toplam 28 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Ağız ve Çene Cerrahisi, Oral İmplantoloji
Bölüm Derlemeler
Yazarlar

Aslışah Aktunç 0009-0009-6495-5600

Yayımlanma Tarihi 27 Aralık 2024
Gönderilme Tarihi 19 Nisan 2024
Kabul Tarihi 11 Aralık 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 3 Sayı: 3

Kaynak Göster

Vancouver Aktunç A. Diş Hekimliğinde Enjekte Edilebilir Kemik Greftlerinin Kullanımı. J Turkish Dent Res. 2024;3(3):452-8.

Türk Diş Hekimliği Araştırma Dergisi Creative Commons Atıf-GayriTicari 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Dergimize Diş Hekimliği alanından yayın kabulü yapılmaktadır. Diğer alanlardan gönderilen yayınlar değerlendirmeye alınmamaktadır.