This study deals with electrochemical preparation of cobalt oxide modified glassy carbon electrodes decorated with gold nanoparticles as an effective platform for dopamine (DA) detection. The experimental parameters affecting the oxidation signal of DA by square wave voltammetry have been evaluated. Under optimal conditions, developed sensor exhibited a linear response towards to DA in the concentration range of 6.0 10−8 to 7.5 10−6 M. The detection and quantification limits were calculated as 2.0 10−8 and 6.0 10−8M, respectively. The repeatability and reproducibility of the electrode were calculated as 13.2 and 16.1 % for 6.5 10-7 M (N = 3), respectively. Finally, the sensor was successfully applied for the DA analysis in artificial cerebrospinal fluid, and the mean recovery was found as 105.8 ±6.5 % by standard addition method.
Primary Language | English |
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Subjects | Analytical Chemistry |
Journal Section | Research Articles |
Authors | |
Publication Date | June 23, 2020 |
Submission Date | April 7, 2020 |
Acceptance Date | May 17, 2020 |
Published in Issue | Year 2020 Volume: 2 Issue: 1 |