Parentucellia viscosa (growing in Türkiye): Essential oil, phenolic composition, antimicrobial and lipase inhibition

Year 2024, Volume: 6 Issue: 2, 91 - 96, 20.12.2024

Büşra Korkmaz , Gözde Kılıç , Büşra Şahin , Sıla Özlem Sener , Elif Öztürk , Seda Fandakli , Şengül Alpay Karaoğlu , Nurettin Yaylı

https://doi.org/10.51435/turkjac.1513093

Abstract

The essential oil (EO) and phenolic constituents of Parentucellia viscosa L. were analyzed by GC-FID-MS and HPLC, respectively. A total of 20 volatile compounds were identified accounting for 99.97% in hydrodistillation. Monoterpenes (50.57%, 5 compounds) were the primary chemical class in the essential oil of P. viscosa. Limonene (44.02%) and 1-octen-3-ol (25.23%) were the major components in the essential oil of P. viscosa. The phenolic constituent analysis for the methanol extract of P. viscosa gave benzoic acid (0.97 mg/g) as the major compound. The antimicrobial activities of the EO and crude solvent (n-hexane, acetonitrile, methanol, and water) extracts of P. viscosa were screened in vitro against ten microorganisms. n-Hexane and the acetonitrile extracts of P. viscosa resulted in the best activity against Mycobacterium smegmatis with IC50 values of 19.2 µg/mL and 53.8 µg/mL, respectively. The highest lipase enzyme inhibition activity was detected in the n-hexane extract with 44.22±1.1628 µg/mL IC50 value.

Keywords

Parentucellia viscosa, essential oil, phenolic, antimicrobial, lipase

Parentucellia viscosa (growing in Türkiye): Essential oil, phenolic composition, antimicrobial and lipase inhibition

Abstract

References

• A. Güner, S. Aslan, T. Ekim, M. Vural, M. T. Babaç, Türkiye Plants List; Vascular Plants, Nezahat Gökyiğit Botanical Garden and Flora Research Association Publication, 2012, 657.
• N. Badalamenti, M. Bruno, C. Formisano, and D. Rigano, Effect of Germacrene-Rich Essential Oil of Parentucellia latifolia (L.) Caruel Collected in Central Sicily on the Growth of Microorganisms Inhabiting Historical Textiles, Nat Prod Comm, 17(4), 2022, 1934578X221096963.
• A. Venditti, M. Ballero, M. Serafini, A. Bianco, Polar compounds from Parentucellia viscosa (L.) Caruel from Sardinia, Nat Prod Res, 29(7), 2015, 602-606.
• J. Pate, T. Bell, Host associations of the introduced annual root hemiparasite Parentucellia viscosa in agricultural and bushland settings in Western Australia, Ann Bot, 85(2), 2000, 203-213.
• T.T. Liu, X.T. Liu, Q.X. Chen, Y. Shi, Lipase inhibitors for obesity: A review, Biomed Pharmacother, 128, 2020, 110314.
• A. Bianco, P. Passacantilli, G. Righi, M. Nicoletti, Iridoid glucosides from Parentucellia viscosa, Phytochemistry, 24(8), 1985, 1843-1845.
• M. Grande, A. Fernández-Mateos, J.J. Blanco, M.M. Herrador, J.F.Q. del Moral, P. Arteaga, J.F. Arteaga, A.F. Barrero, Diversity on Diterpene Composition in Two Populations of Parentucellia viscosa: Labdane and Clerodane Chemotypes, Nat Prod Commun, 2(6), 2007, 621-624.
• E.J. Llorent-Martínez, M.L. Fernández-de Córdova, G. Zengin, M.B. Bahadori, M.Z. Aumeeruddy, K.R. Rengasamy, M.F. Mahomoodally, Parentucellia latifolia subsp. latifolia: A potential source for loganin iridoids by HPLC-ESI-MSn technique, J Pharm Biomed, 165, 2019, 374-380.
• J. Urones, I. Marcos, I.Cubillo, N.M. Garrido, P. Basabe, Terpenoid compounds from Parentucellia latifolia, Phytochemistry, 29(7), 1990, 2223-2228.
• J. Urones, I. Marcos, L. Cubillo, V. Monje, J. Hernández, P. Basabe, Derivatives of malonic acid in Parentucellia latifolia, Phytochemistry, 28(2), 1989, 651-653.
• Z. Amar, S.N. Labib, G. Noureddine, R. Salah, Phytochemical screening of five Algerian plants and the assessment of the antibacterial activity of two Euphorbia guyoniana extracts, Pharmacia Lettre, 4(5), 2012, 1438-1444.
• R.P. Adams, Identification of essential oil components by gas chromatography/mass spectrometry: Allured publishing corporation Carol Stream, IL, 2007.
• G. Kılıç, B. Korkmaz, İ. Erik, S. Fandaklı, S.S. Yaylı, Ö. Faiz, Ş. Alpay Karaoğlu, N. Yaylı, Antimicrobial, antioxidant, tyrosinase activities and volatile compounds of the essential oil and solvent extract of Epilobium hirsutum L. growing in Turkey, Turk J Chem, 2(2), 2020, 87-94.
• İ. Erik, G. Kılıç, E. Öztürk, Ş.A. Karaoğlu, N. Yaylı, Chemical composition, antimicrobial, and lipase enzyme activity of essential oil and solvent extracts from Serapias orientalis subsp. orientalis, Turk J Chem, 44(6), 2020, 1655-1662.
• N. Yayli, A. Yaşar, C. Güleç, A. Usta, S. Kolaylı, K. Coşkunçelebi, S.A. Karaoğlu, Composition and antimicrobial activity of essential oils from Centaurea sessilis and Centaurea armena, Phytochemistry, 66(14), 2005, 1741-1745.
• N. Yayli, E. Oksuz, B. Korkmaz, İ. Erik, S. Fandakli, Ö. Faiz Ö, K. Coşkunçelebi, Volatile and Phenolic Contents, Antimicrobial and Tyrosinase activities of Two Endemic Species Scorzonera pisidica and Scorzonera sandrasica L. Grown in Turkey, Rec Nat Prod, 16(1), 2022, 46-57.
• I. Erik, G. Kılıç, B. Korkmaz, S. Fandaklı, Ş.A. Karaoğlu, N. Yaylı, Volatile constituents and antimicrobial activity of Vinca major L. subsp. hirsuta (Boiss) stearn grown in Turkey, J Res Pharm, 25(5), 2021, 581-588.
• N. Yayli, C. Gülec, O. Üçüncü, A. Yaşar, S. Ülker, K. Coşkunçelebi, S. Terzioğlu, Composition and antimicrobial activities of volatile components of Minuartia meyeri, Turk J Chem, 30(1), 2006, 71-76.
• T.B. Cansu, B. Yayli, T. Özdemir, N. Batan, Ş.A. Karaoğlu, N. Yaylı, Antimicrobial activity and chemical composition of the essential oils of mosses (Hylocomium splendens (Hedw.) Schimp. and Leucodon sciuroides (Hedw.) Schwägr.) growing in Turkey, Turk J.Chem, 37(2), 2013, 213-219.
• O.D. Sparkman, Identification of essential oil components by gas chromatography/quadrupole mass spectroscopy, J Am Soc Mass Spectrom, 16(11), 2005, 1902.
• N. Korkmaz, S.O. Sener, N. Balturk, S. Kanbolat, M. Badem, R. Aliyazicioglu, U. Ozgen, A. Kandemir, S. Alpay Karaoglu, Determination of Phenolic Contents by HPLC, and Antioxidant, Antimicrobial, Antityrosinase,and Anticholinesterase Activitiesof Psephellus huber-morathii, J Pharm Res Int, 26(1), 2019, 1-10.
• A.L. Barry, Methods for determining bactericidal activity of antimicrobial agents: approved guideline, National Committee for Clinical Laboratory Standards: National Committee for Clinical Laboratory Standards Wayne, PA, 1999.
• G.L. Woods, Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes, Approved Standard M24-A2, 31(5), 2011.
• N. Andriamaharavo, Retention Data NIST Mass Spectrometry Data Center, NIST Mass Spectrometry Data Center, 2014.
• G.L. Woods, B.A. Brown-Elliott, E.P. Desmond, G.S. Hall, L. Heifets, G.E. Pfyffer, Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes. pproved standard, NCCLS document M24-A, 23(18), 2003.
• S.O. Sener, U. Ozgen, S. Kanbolat, N. Korkmaz, M. Badem, H. Hanci, T. Dirmenci, T. Arabaci, R. Aliyazicioglu, E. Yenilmez, G. Saltan Işcan, Investigation of therapeutic potential of three endemic Cirsium species for global health problem obesity, S Afr J Bot, 141, 2021, 243-254.