THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS

Volume: 3 Number: 2 December 1, 2013
  • S. Pamuk
  • I. Atac
EN

THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS

Abstract

In this paper we present the method of lines to obtain the numerical solution of a mathematical model for the roles of endothelial, pericyte and macrophage cells in the initiation of tumor angiogenesis. This method is an approach to the numerical solution of partial differential equations that involve a time variable t and a space variable x. We provide computer programs written in Matlab. Also, the stability analysis of the solutions is given, and the figures for endothelial, pericyte and macrophage cell movements in the capillary are presented for large times

Keywords

References

  1. Ahmad, I. and Berzins, M., (2001), MOL solvers for hyperbolic PDEs with source terms, Math. Comput. Simulat., 56 (2), 115-125.
  2. Erdem, A. and Pamuk, S., (2007), The method of lines for the numerical solution of a mathematical model for capillary formation: The role of tumor angiogenic factor in the extra-cellular matrix, Appl. Math. Comput., 186, 891-897.
  3. Korn, G.A., (1999), Interactive solution of partial differential equations by the Method-of-lines, Math. Comput. Simulat., 49 (1-2), 129-138.
  4. Levine, H.A., Sleeman, B.D. and Nilsen-Hamilton, M., (2000), A mathematical model for the roles of pericytes and macrophages in the initiation of angiogenesis. I.The role of protease inhibitors in preventing angiogenesis, Math. Biosc., 168, 77-115.
  5. Mikhail, M.N., (1987), On the validity and stability of the method of lines for the solution of partial differential equations, Appl. Math. Comput., 22 (2-3), 89-98.
  6. Pamuk, S. and Erdem, A., (2007), The method of lines for the numerical solution of a mathematical model for capillary formation: The role of endothelial cells in the capillary, Appl. Math. Comput., 186, 831-835.
  7. Pamuk, S., (2003), Qualitative analysis of a mathematical model for capillary formation in tumor angiogenesis, Math. Models and Methods Apll. Sci., 13 (1), 19-33.
  8. Schor, A.M., CanŞeld, A.E., Sutton,A.B., Allen,T.D., Sloan,P., Schor, S.L., Steiner,R., Weisz, P.B. and Langer,R., (1992), The behavior of pericytes in vitro: relevance to angiogenesis and differentiation, Angiogenesis: Key Principles-Science-Technology-Medicine, Birkhauser, Basel.

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

S. Pamuk This is me

I. Atac This is me

Publication Date

December 1, 2013

Submission Date

-

Acceptance Date

-

Published in Issue

Year 2013 Volume: 3 Number: 2

APA
Pamuk, S., & Atac, I. (2013). THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS. TWMS Journal of Applied and Engineering Mathematics, 3(2), 182-197. https://izlik.org/JA23KU59CM
AMA
1.Pamuk S, Atac I. THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS. JAEM. 2013;3(2):182-197. https://izlik.org/JA23KU59CM
Chicago
Pamuk, S., and I. Atac. 2013. “THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS”. TWMS Journal of Applied and Engineering Mathematics 3 (2): 182-97. https://izlik.org/JA23KU59CM.
EndNote
Pamuk S, Atac I (December 1, 2013) THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS. TWMS Journal of Applied and Engineering Mathematics 3 2 182–197.
IEEE
[1]S. Pamuk and I. Atac, “THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS”, JAEM, vol. 3, no. 2, pp. 182–197, Dec. 2013, [Online]. Available: https://izlik.org/JA23KU59CM
ISNAD
Pamuk, S. - Atac, I. “THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS”. TWMS Journal of Applied and Engineering Mathematics 3/2 (December 1, 2013): 182-197. https://izlik.org/JA23KU59CM.
JAMA
1.Pamuk S, Atac I. THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS. JAEM. 2013;3:182–197.
MLA
Pamuk, S., and I. Atac. “THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS”. TWMS Journal of Applied and Engineering Mathematics, vol. 3, no. 2, Dec. 2013, pp. 182-97, https://izlik.org/JA23KU59CM.
Vancouver
1.S. Pamuk, I. Atac. THE METHOD OF LINES FOR THE NUMERICAL SOLUTION OF A MATHEMATICAL MODEL IN THE INITIATION OF ANGIOGENESIS. JAEM [Internet]. 2013 Dec. 1;3(2):182-97. Available from: https://izlik.org/JA23KU59CM