Ileal Perforation Caused by Typhoid Fever

Year 2015, , 86 - 89, 01.07.2015

Sevgi Buyukbese Sarsu , Ali Karapur

https://doi.org/10.5455/umj.20150827014908

Abstract

Background: Typhoid fever is a systemic infectious disease specific to human beings which is caused by a gram-negative bacillus Salmonella typhi . Its incidence demonstrates significant variations in different regions of the world. It is generally seen in children of the school age. In developing countries, its most widely seen, and serious complication is intestinal perforation IP . IP is generally seen within the third week of the disease. In children, it can onset with necrotic ileal Peyer’s patches which progress to diffuse peritonitis if not treated with appropriate medical therapy or in cases of delayed diagnosis. In these conditions, it requires surgical treatment . Despite novel antibiotics, and improvements in surgical techniques, mortality rates still range between 9, and 22 percent. Conclusion: This case report aims to distract attention to the importance of appropriate, and timely surgical intervention in a 15-year-old boy who presented with terminal ileum perforation developed secondary to inappropriately treated typhoid fever.

Keywords

Fournier’s gangrene, coronary artery bypass, extracorporeal circulation, therapy

References

• Ukwenya AY, Ahmed A, Garba ES: Progress in management of typhoid perforation. Ann Afr Med 2011, 10:259-65.
• Tade AO, Olateju SO, Osinupebi OA, Salami BA: Typhoid Intestinal Perforations in a Tropical Tertiary Health Facility: A Prospective Study. East Cent Afr J Surg 2011; 16(2):72.
• Caronna R, Boukari AK, Zaongo D, et al. Comparative analysis of primary repair vs resection and anastomosis, with laparotomy, in management of typhoid intestinal perforation: results of a rural hospital in northwestern Benin. BMC Gastroenterol 2013; 13: 102.
• Mogasele V, Desai SN, Mogasele VV, Park JK, Ochiai RL, Wierzba TF. Case fatality rate and length of hospital stay among patients with typhoid intestinal perforation in developing countries: A systematic literature review. Plos One 2014; 9
• Khan SH, Aziz SA, Ul-Haq MI: Perforated peptic ulcers: A review of 36 cases. Professional Med J 2011; 18(1):124-127.
• Ugochukwu AI, Amu OC, Nzegwu MA. Ileal perforation due to typhoid fever e Review of operative management and outcome in an urban centre in Nigeria. International Journal of Surgery ; 218-222. Faisal G. Bhopal, Faryal Azhar, Naseer-Ud-Din, Tausief Fatima: selective manafement of typhoid perforation of Bowel. Journal of surgery Pakistan (International) 2011; 16(3):123-6.
• Goyal S, Singla S, Goyal S. Surgical Management of Enteric Perforation by Using Omental Patch: A Prospective Study of 60 Patients Arch Clin Exp Surg 2013;2: 80-84.
• Agu ZK, Nzegwu M, Obi E. Prevelance, morbidity, and mortality patterns of typhoid ileal perforations as seen at the University of Nigeria Teaching Hospital Enugu Nigeria: An 8- year review. World J Surg 2014; 38: 2514-8.
• Deepak Shrivastava AD, Jain Amit Kumar JA, Gharde Pankaj, Bala SD, Ram Sewak VR. Typhoid intestinal perforation in Central India – A surgical experience of 155 cases in resource limited setting. International Journal of Biomedical And Advance Research. IJBAR 2014; 05:12.
• Chalya PL, Mabula JB, Koy M, Kataraihya JB, Hyasinta Jaka H, Mshana SE, Mariam Mirambo M, Mchembe MD, Giiti G, Gilyoma JM. Typhoid intestinal perforations at a University teaching hospital in Northwestern Tanzania: Surgical experience of 104 cases in a resource-limited setting World Journal of Emergency Surgery 2012,(3) 7:4.