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A Rarely Seen Hepatic Tumor: Epithelioid Hemangioendothelioma

Year 2016, , 59 - 62, 01.01.2016
https://doi.org/10.5455/umj.20160121062843

Abstract

Introduction: Epithelioid Hemangioendothelioma EHE is a rarely seen tumor most frequently originating from vascular structures of different regions including liver, followed by stomach, spleen, lung, bone, soft tissue, and skin. Case Presentation: In this paper, a patient with multiple mass lesions in the liver with a diagnosis of EHE who underwent liver transplantation is presented. Conclusion: It has an intermediate degree of malignancy between benign hemangioma, and malignant hemangiosarcoma. It can manifest with nonspecific symptoms or hepatic failure. Generally it is seen as a diffuse hepatic disease. The most optimal treatment alternatives are liver resection, and transplantation.

References

  • Dong K, Wnag X, Feng JL et al. Pathological characteristics of liver biopsies in eight patients with hepatic epithelioid hemangio endothelioma. Int J Clin Exp Pathol 2015;8(9): 11015-23.
  • Pregliasco AG, Wendum D, Goumard C et al. Hepatic epithelioid hemangioendothelioma. Clin Res Hepatol Gastroenterol 2015 Nov pii: S2210-7401(15)00254-5.
  • Mehrabi A, Kashfi A, Fonouni H et al. Primary malignant hepatic epithelioid hemangioendothelioma: A comprehensive rewiew of the literature with emphasis on the surgical therapy. Cancer ;107:2108-21.
  • Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: A vascular tumor often mistaken for a carcinoma. Cancer ;50:970-81 . Sangro B, Inaarrairaegui M, Fernandez-Ros N. Malignant epitheloid hemangioendothelioma of the liver successfully treated with sorafenib. Rare Tumors 2012;4:e34 .
  • Caruso S, Miraglia R, Maruzelli L et al. An unusual presentation of malignant hepatic epithelioid hemangioendothelioma with left pleural and pulmonary localization.Pediatr Radiol 2008;38:1027-30
  • Ji ZF, Shen XZ, Zhang DY et al. Hepatic epithelioid hemangio endothelioma: a report of six patients. J Dig Dis 2010;11:254-8.
  • Tsuneyoshi M, Dorfman HD, Bauer TW. Epithelioid hemangio endothelioms of bone: a clinicopathologic, ultrastructural, and immunohistochemical study. Am J Surg Pathol 1986;10:754-64.
  • Langrehr JM, Petersen I, Pfitzmann R, Lopez-Hanninen E. Malignant epithelioid hemangioendothelioma of the liver. Result of surgical treatment strategies. Chirurg 2005;76:1161-7.
  • Lerut JP, Orlando G, Sempoux C et al. Hepatic hemangio endothelioma in adults: Excellent outcome following liver transplantation. Transpl Int 2004;17:202-07.
  • Ben-Haim M, Roayaise S, Ye MQ et al. Hepatic epithelioid hemangioendothelioma: Resection or transplantation, which and when? Liver Transpl Surg 1999;5:526-31.
  • Lerut JP, Orlando G, Adam R. The place of liver transplantation in the treatment of hepatic epitheloid hemangioendothelioma: report of the European liver transplant registry. Ann Surg. 2007 Dec;246(6):949-57.
Year 2016, , 59 - 62, 01.01.2016
https://doi.org/10.5455/umj.20160121062843

Abstract

References

  • Dong K, Wnag X, Feng JL et al. Pathological characteristics of liver biopsies in eight patients with hepatic epithelioid hemangio endothelioma. Int J Clin Exp Pathol 2015;8(9): 11015-23.
  • Pregliasco AG, Wendum D, Goumard C et al. Hepatic epithelioid hemangioendothelioma. Clin Res Hepatol Gastroenterol 2015 Nov pii: S2210-7401(15)00254-5.
  • Mehrabi A, Kashfi A, Fonouni H et al. Primary malignant hepatic epithelioid hemangioendothelioma: A comprehensive rewiew of the literature with emphasis on the surgical therapy. Cancer ;107:2108-21.
  • Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: A vascular tumor often mistaken for a carcinoma. Cancer ;50:970-81 . Sangro B, Inaarrairaegui M, Fernandez-Ros N. Malignant epitheloid hemangioendothelioma of the liver successfully treated with sorafenib. Rare Tumors 2012;4:e34 .
  • Caruso S, Miraglia R, Maruzelli L et al. An unusual presentation of malignant hepatic epithelioid hemangioendothelioma with left pleural and pulmonary localization.Pediatr Radiol 2008;38:1027-30
  • Ji ZF, Shen XZ, Zhang DY et al. Hepatic epithelioid hemangio endothelioma: a report of six patients. J Dig Dis 2010;11:254-8.
  • Tsuneyoshi M, Dorfman HD, Bauer TW. Epithelioid hemangio endothelioms of bone: a clinicopathologic, ultrastructural, and immunohistochemical study. Am J Surg Pathol 1986;10:754-64.
  • Langrehr JM, Petersen I, Pfitzmann R, Lopez-Hanninen E. Malignant epithelioid hemangioendothelioma of the liver. Result of surgical treatment strategies. Chirurg 2005;76:1161-7.
  • Lerut JP, Orlando G, Sempoux C et al. Hepatic hemangio endothelioma in adults: Excellent outcome following liver transplantation. Transpl Int 2004;17:202-07.
  • Ben-Haim M, Roayaise S, Ye MQ et al. Hepatic epithelioid hemangioendothelioma: Resection or transplantation, which and when? Liver Transpl Surg 1999;5:526-31.
  • Lerut JP, Orlando G, Adam R. The place of liver transplantation in the treatment of hepatic epitheloid hemangioendothelioma: report of the European liver transplant registry. Ann Surg. 2007 Dec;246(6):949-57.
There are 11 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Erdinc Nayir

Publication Date January 1, 2016
Published in Issue Year 2016

Cite

Vancouver Nayir E. A Rarely Seen Hepatic Tumor: Epithelioid Hemangioendothelioma. ULUTAS MED J. 2016;2(1):59-62.