Psoriasis and Schizophrenia: An Interesting Association

Year 2019, , 95 - 96, 01.01.2019

N.a. Bishurul Hafi N.a. Uvais

https://doi.org/10.5455/umj.20191107033209

Abstract

Among the all psycho-dermatologic associations, one of the most discussed topics is the striking relationship between psoriasis and schizophrenia. There are multiple controlled trials as well as meta-analyses on this subject and interesting theories have been developed. We are trying to compile and concise the available information and to present it in a structured way for better understanding, through this letter.

Keywords

Psoriasis, schizophrenia, associations

References

• Debnath M, Berk M. Th17 pathway-mediated immunopathogenesis of schizophrenia: mechanisms and implications. Schizophr Bull 2014;40:1412–1421.
• Di Nuzzo S, Zanni M, De Panfilis G. Exacerbation of paranoid schizophrenia in a psoriatic patient after treatment with cyclosporine A, but not with etanercept. J Drugs Dermatol 2007;6:1046–1047.
• Riedmuller R, Muller S. Ethical implications of the mild encephalitis hypothesis of schizophrenia. Front Psychiatry 2017;8:38.
• Yang YW, Lin HC. Increased risk of psoriasis among patients with schizophrenia: a nationwide population-based study. Br J Dermatol 2012;166:899–900.
• Ungprasert P, Wijarnpreecha K, Cheungpasitporn W. Patients with schizophrenia have a higher risk of psoriasis: A systematic review and meta-analysis. Psychiatry Research 2018;259:422–426.
• Kumar V, Mattoo SM, Handa S. Psychiatric morbidity in pemphigus and psoriasis: a comparative study from India. Asian J Psychiatry 2013;6:151–156.
• Miyaoka T, Seno H, Inagaki T, et al. Schizophrenia associated with psoriasis vulgaris: three case reports. Schizophr Res 2000;41:383–386.
• Shimamoto Y, Shimamoto H. Annular pustular psoriasis associated with affective psychosis. Cutis 1990;45:439–442.
• Latini A, Carducci M. Psoriasis during therapy with olanzapine. Eur J Dermatol 2003;13:404–405.
• Ascari-Raccagni A, Baldari U, Rossi E, Alessandrini F. Exacerbation of chronic large plaque psoriasis associated with Olanzepine therapy. J Eur Acad Dermatol Venereol 2000;14:315–316.
• Kaufman KR. Etanercept, anticytokines and mania. Int Clin Psychopharmacol 2005;20:239–241. How to cite?