A Rare Case: Hyperacute Anterior MI Following Plant-Based Drug Use

Year 2020, , 87 - 90, 23.06.2020

Ferit Böyük

https://doi.org/10.5455/umj.20200504101042

Abstract

Introduction: Acute myocardial infarction (AMI) is one of the foremost reasons of cardiovascular diseases, which may be fatal in a lack of early diagnosis and treatment. Risk factors associated with the disease among the elderly population are fairly straight forward, however among the under-40 age group; they are yet to be unveiled in its completeness. AMI patients under 40 years of age should be questioned especially about cocaine addiction and other drug use in addition to the classic risk factors for coronary artery disease.
Case Presentation: In this case report, we discuss a 35-year-old patient who had Acute anterior myocardial infarction as a result of uncontrolled use of ginseng, lepidium, and epimedium containing herbal medicines due to infertility and who had no other apparent risk factor.

Keywords

Acute anterior myocardial infarction, herbal drug, infertility

References

• Schoenenberger AW, Radovanovic D, Stauffer JC, Windecker S, Urban P, et al. Acute coronary syndromes in young patients: Presentation, treatment and outcome International Journal of Cardiology. 2011;148:304-308
• Gillis CN. Panax ginseng pharmacology: a nitric oxide link? Biochem Pharmacol 1997;54:1-8
• Ding DZ, Shen TK, Cui YZ. Effects of red Ginseng on the congestive heart failure and its mechanism. Article in Chinese Zhongguo Zhong Xi Yi Jie He Za Zhi 1995;15:325-7
• Yi F, Tan XL, Yan X, Liu HB , In silico profiling for secondary metabolites from Lepidium meyenii by the pharmacophore and ligand-shape-based joint approach, Published online. Chin Med. 2016;11:42
• Arief ZM, Munshi AH, Shawl AS, Evaluation of medicinal value of Epimedium elatum on the basis of pharmacologically active constituents, Icariin and Icariside- II, Pak J Pharm Sci. 2015;28(5):1665-9
• Gunes H, Kucukdurmaz Z, Karapinar H, Gul I. Acute anterior myocardial infarction presented with cardiogenic shock in a patient on herbal medication. Turk Kardiyol Dern Ars, 40, 262-264
• Martínez-Mir I, Rubio E, Morales-Olivas FJ, Palop-Larrea V. Transient ischemic attack secondary to hypertensive crisis related to Panax ginseng. Annals of Pharmacotherapy, 38, 1970–1970
• Zhai M, He L, Ju X, Shao L, Li G, Zhang Y, Liu Y, Zhao H, Icariin Acts as a Potential Agent for Preventing Cardiac Ischemia/Reperfusion Injury. Cell Biochem Biophys. 2015;72(2):589-97
• Han KH, Choe SC, Kim HS, Sohn DW, Nam KY, Oh BH, et al. Effect of red ginseng on blood pressure in patients with essential hypertension and White coat hypertension. Am J Chin Med 1998;26:199-209
• Siegel RK. Ginseng abuse syndrome. Problems with the panacea. JAMA 1979;241:1614-5