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Suicidal Death from Pseudoephedrine Sulfate Overdose: A Case Report

Year 2015, Volume: 1 Issue: 4, 119 - 121, 01.10.2015
https://doi.org/10.5455/umj.20151110010021

Abstract

Background: Upper respiratory tract infections are common in the community and pseudoephedrine preparations are widely used in the treatment as a decongestant drug. However, pseudoephedrine has serious side effects on the central nervous system and the cardiovascular system. Although cases of infant death due to overdose have been reported in literature, pseudoephedrine toxicity has not been observed in adults as a cause of suicide in literature. Case Presentation: The case is an 18-year old female who committed suicide with pseudoephedrine sulfate preparation. Care and attention must be paid as pseudoephedrine preparations are easily accessible, widely used and an overdose can cause death in adults.

References

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  • Gülhan B, Bayrakcı B, Babaoglu M Ö, Bal B, Beken S. Biphasic reatin kinase elevation in pseudoephedrine overdosage. Br J Clin Pharmacol 2008; 67:139–140.
  • Soyer T, Göl IH, Eroğlu F, Cetin A. Acute urinary retention due to pseudoephedrine hydrochloride in a 3-year-old child. Turk J Pediatr. 2008; 50:98-100.
  • Roberge RJ, Hirani KH, Rowland PL 3rd, Berkeley R, Krenzelok EP. Dextromethorphan- And Pseudoephedrine- Induced Agitated Psychosis And Ataxia. J Emerg Med. 1999 Mar-Apr;17:285-8.
  • Brunton L, Chabner B, Knollman B, eds. Goodman& Gilman’s The Pharmacological Basis Of Therapeutics. 12th edn. China: The McGraw Hill Company; 2011.
  • Marinetti L, Lehman L, Casto B, Harshbarger K, Kubiczek P, Davis J, Over-the-Counter Cold Medications – Postmortem Findings in Infants and the Relationship to Cause of Death. Journal of Analytical Toxicology. 2005; 29:738-743.
  • Olson K. R, Lange Zehirlenmeler & ilaç Aşırı Dozu. Istanbul: Nobel Tıp Kitapevi. 2012.
  • Kutluhan S. Özen A. Gökalp O. Gültekin F. Psödoefedrin ile Tetiklenen Epileptik Nöbet. Türk Nöroloji Dergisi. ;14:357-359. Aypak C,Türedi Ö,Yüce A, Görpelioğlu S. A Serious Adverse Effect of Pseudoephedrine Used For Common Cold Treatment : Ventricular Arrhythmia. Cukurova Med J 2013; : 506-510.
  • Tahmaz M, Kumbasar B, Ozturk S,Kazancioglu R. Pseudoephedrine-induced Ventricular Tachycardia. Eur J Gen Med 2013; 10:77-80.
  • Loizou LA, Hamilton JG, Tsementzis SA. Intracranial hemorrhagein association with pseudoephedrine overdose (letter). J Neurol, Neurosurg Psychiatr 1982;45:471–2. DOI: dx.doi.org/10.5455/umj.20151110010021
  • Cite article as: Petekkaya S, Ayaz N, Dogan M, Oruc M, Oner BS, Gokturk C, Celebi A, Budak AE, Soylu O, Celbis O. Suicidal Death from Pseudoephedrine Sulfate Overdose: A Case Report. Ulutas Med J. 2015;1(4):119-121
Year 2015, Volume: 1 Issue: 4, 119 - 121, 01.10.2015
https://doi.org/10.5455/umj.20151110010021

Abstract

References

  • Kayaalp O, Akılcıl Tedavi Yönünden Tıbbi Farmakoloji ; 2 (13): 1022-1023. Ankara. Pelikan Kitabevi.
  • Gülhan B, Bayrakcı B, Babaoglu M Ö, Bal B, Beken S. Biphasic reatin kinase elevation in pseudoephedrine overdosage. Br J Clin Pharmacol 2008; 67:139–140.
  • Soyer T, Göl IH, Eroğlu F, Cetin A. Acute urinary retention due to pseudoephedrine hydrochloride in a 3-year-old child. Turk J Pediatr. 2008; 50:98-100.
  • Roberge RJ, Hirani KH, Rowland PL 3rd, Berkeley R, Krenzelok EP. Dextromethorphan- And Pseudoephedrine- Induced Agitated Psychosis And Ataxia. J Emerg Med. 1999 Mar-Apr;17:285-8.
  • Brunton L, Chabner B, Knollman B, eds. Goodman& Gilman’s The Pharmacological Basis Of Therapeutics. 12th edn. China: The McGraw Hill Company; 2011.
  • Marinetti L, Lehman L, Casto B, Harshbarger K, Kubiczek P, Davis J, Over-the-Counter Cold Medications – Postmortem Findings in Infants and the Relationship to Cause of Death. Journal of Analytical Toxicology. 2005; 29:738-743.
  • Olson K. R, Lange Zehirlenmeler & ilaç Aşırı Dozu. Istanbul: Nobel Tıp Kitapevi. 2012.
  • Kutluhan S. Özen A. Gökalp O. Gültekin F. Psödoefedrin ile Tetiklenen Epileptik Nöbet. Türk Nöroloji Dergisi. ;14:357-359. Aypak C,Türedi Ö,Yüce A, Görpelioğlu S. A Serious Adverse Effect of Pseudoephedrine Used For Common Cold Treatment : Ventricular Arrhythmia. Cukurova Med J 2013; : 506-510.
  • Tahmaz M, Kumbasar B, Ozturk S,Kazancioglu R. Pseudoephedrine-induced Ventricular Tachycardia. Eur J Gen Med 2013; 10:77-80.
  • Loizou LA, Hamilton JG, Tsementzis SA. Intracranial hemorrhagein association with pseudoephedrine overdose (letter). J Neurol, Neurosurg Psychiatr 1982;45:471–2. DOI: dx.doi.org/10.5455/umj.20151110010021
  • Cite article as: Petekkaya S, Ayaz N, Dogan M, Oruc M, Oner BS, Gokturk C, Celebi A, Budak AE, Soylu O, Celbis O. Suicidal Death from Pseudoephedrine Sulfate Overdose: A Case Report. Ulutas Med J. 2015;1(4):119-121
There are 11 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Semih Petekkaya This is me

Nusret Ayaz This is me

Mustafa Dogan This is me

Mucahit Oruc This is me

Bedirhan Sezer Oner This is me

Cihan Gokturk This is me

Ahmet Celebi This is me

Adalet Eda Budak This is me

Ozcan Soylu This is me

Osman Celbis This is me

Publication Date October 1, 2015
Published in Issue Year 2015 Volume: 1 Issue: 4

Cite

Vancouver Petekkaya S, Ayaz N, Dogan M, Oruc M, Oner BS, Gokturk C, Celebi A, Budak AE, Soylu O, Celbis O. Suicidal Death from Pseudoephedrine Sulfate Overdose: A Case Report. ULUTAS MED J. 2015;1(4):119-21.