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A Multiple Sclerosis Case Presenting Mixed State Bipolar Affective Disorder as Initial Sign

Year 2016, Volume: 2 Issue: 1, 52 - 54, 01.01.2016
https://doi.org/10.5455/umj.20160322030336

Abstract

Introduction: Multiple sclerosis MS is a chronic, progressive, inflammatory and demyelinating disease of the central nervous system that commonly affects young adults and which may lead to various physical disabilities. It has been reported that bipolar disorder is twice more common among MS patients compared to the normal population. The comorbidity of MS and bipolar disorder, which has not been sufficiently studied until now, is a relatively common state. A variety of mechanisms have been proposed to explain this comorbidity. It has been suggested that bipolar disorder in MS patients may be a sign of the disease, a concurrently diagnosed condition, or a side effect of the drugs such as corticosteroids used for therapeutic purposes. Conclusion: The aim of this manuscript was to describe a case of multiple sclerosis that presented mixed state bipolar affective disorder as its initial sign, and to discuss this case in light of the literature.

References

  • Childs 1.Gilroy JM. Basic Neurology. 3th ed. Mc Graw Hill 2000; 199-224.
  • Figved N, Klevan G, et al. Neuropsychiatric symptoms in patients with multiple sclerosis. Acta PsychiatrScand 2005;112:463-8.
  • Galeazzi GM, Ferrari S, Giaroli G, et al. Psychiatric disorders and depression in multiple sclerosis out patients: impact of disabilityand interferon-beta therapy. NeurolSci 2005; 26:255-62.
  • Uguz F, Akpinar Z, Ozkan I, Tokgoz S. Mood and anxiety disorders in patients with multiple sclerosis. Int J Psychiatry Clin Pract 2008; 12:19-24.
  • Siegert RJ, Abernethy DA. Depression in multiple sclerosis: a review. J Neurol Neurosurg Psychiatry 2005; 76:469-75.
  • Oral ET, Yalçıner B, Karadağ F, Sarı H, Verimli A. Monopolar Mania and/or Multiple Sclerosis: A case report. Düşünen Adam. 1994; 7:30-3.
  • Heila H, Turpeinen P, Erkinjuntti T. Case study: mania associated with multiple sclerosis. J Am Acad Child Adolesc Psychiatry. 1995; 34:1591-5.
  • Ybarra MI, Moreira MA, Araşjo CR, Lana-Peixoto MA, Teixeira AL. Bipolar disorder and multiple sclerosis. Arq Neuro psiquiatr 2007; 65:1177-80.
  • Schiffer RB, Weitkamp LR, Wineman NM, Guttornsem S. Multiple sclerosis and affective disorder: family history, sex, and HLA-DR antigens. ArchNeurol. 1988; 45:1345-8.
  • Konradi C, Sillivan SE, Clay HB. Mitochondria, oligoden-drocytes and inflammation in bipolar disorder: evidence from transcriptome studies points to intriguing parallels with multiple sclerosis. Neurobiol Dis. 2012; 45:37-47.
  • Irkec C, Isık E. Multiple Sclerosis. Organic Psychıatry. 1999;219-248.
  • Minden SL, Schiffer RB. Affective disorders in multiple sclerosis. ArchNeurol 1990; 47:98-104.
  • Boland R. Depression in Medicalillness (Secondary Depression). In: Textbook of Mood Disorders. 1.ed. Stein DJ, Kupfer DJ, Schatzberg AF eds. American Psychiatric Publis-hing, Washington 2006; 642-3.
Year 2016, Volume: 2 Issue: 1, 52 - 54, 01.01.2016
https://doi.org/10.5455/umj.20160322030336

Abstract

References

  • Childs 1.Gilroy JM. Basic Neurology. 3th ed. Mc Graw Hill 2000; 199-224.
  • Figved N, Klevan G, et al. Neuropsychiatric symptoms in patients with multiple sclerosis. Acta PsychiatrScand 2005;112:463-8.
  • Galeazzi GM, Ferrari S, Giaroli G, et al. Psychiatric disorders and depression in multiple sclerosis out patients: impact of disabilityand interferon-beta therapy. NeurolSci 2005; 26:255-62.
  • Uguz F, Akpinar Z, Ozkan I, Tokgoz S. Mood and anxiety disorders in patients with multiple sclerosis. Int J Psychiatry Clin Pract 2008; 12:19-24.
  • Siegert RJ, Abernethy DA. Depression in multiple sclerosis: a review. J Neurol Neurosurg Psychiatry 2005; 76:469-75.
  • Oral ET, Yalçıner B, Karadağ F, Sarı H, Verimli A. Monopolar Mania and/or Multiple Sclerosis: A case report. Düşünen Adam. 1994; 7:30-3.
  • Heila H, Turpeinen P, Erkinjuntti T. Case study: mania associated with multiple sclerosis. J Am Acad Child Adolesc Psychiatry. 1995; 34:1591-5.
  • Ybarra MI, Moreira MA, Araşjo CR, Lana-Peixoto MA, Teixeira AL. Bipolar disorder and multiple sclerosis. Arq Neuro psiquiatr 2007; 65:1177-80.
  • Schiffer RB, Weitkamp LR, Wineman NM, Guttornsem S. Multiple sclerosis and affective disorder: family history, sex, and HLA-DR antigens. ArchNeurol. 1988; 45:1345-8.
  • Konradi C, Sillivan SE, Clay HB. Mitochondria, oligoden-drocytes and inflammation in bipolar disorder: evidence from transcriptome studies points to intriguing parallels with multiple sclerosis. Neurobiol Dis. 2012; 45:37-47.
  • Irkec C, Isık E. Multiple Sclerosis. Organic Psychıatry. 1999;219-248.
  • Minden SL, Schiffer RB. Affective disorders in multiple sclerosis. ArchNeurol 1990; 47:98-104.
  • Boland R. Depression in Medicalillness (Secondary Depression). In: Textbook of Mood Disorders. 1.ed. Stein DJ, Kupfer DJ, Schatzberg AF eds. American Psychiatric Publis-hing, Washington 2006; 642-3.
There are 13 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Musa Sahpolat This is me

Publication Date January 1, 2016
Published in Issue Year 2016 Volume: 2 Issue: 1

Cite

Vancouver Sahpolat M. A Multiple Sclerosis Case Presenting Mixed State Bipolar Affective Disorder as Initial Sign. ULUTAS MED J. 2016;2(1):52-4.