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A Rarely Seen Hepatic Tumor: Epithelioid Hemangioendothelioma

Year 2016, Volume: 2 Issue: 1, 59 - 62, 01.01.2016
https://doi.org/10.5455/umj.20160121062843

Abstract

Introduction: Epithelioid Hemangioendothelioma EHE is a rarely seen tumor most frequently originating from vascular structures of different regions including liver, followed by stomach, spleen, lung, bone, soft tissue, and skin. Case Presentation: In this paper, a patient with multiple mass lesions in the liver with a diagnosis of EHE who underwent liver transplantation is presented. Conclusion: It has an intermediate degree of malignancy between benign hemangioma, and malignant hemangiosarcoma. It can manifest with nonspecific symptoms or hepatic failure. Generally it is seen as a diffuse hepatic disease. The most optimal treatment alternatives are liver resection, and transplantation.

References

  • Dong K, Wnag X, Feng JL et al. Pathological characteristics of liver biopsies in eight patients with hepatic epithelioid hemangio endothelioma. Int J Clin Exp Pathol 2015;8(9): 11015-23.
  • Pregliasco AG, Wendum D, Goumard C et al. Hepatic epithelioid hemangioendothelioma. Clin Res Hepatol Gastroenterol 2015 Nov pii: S2210-7401(15)00254-5.
  • Mehrabi A, Kashfi A, Fonouni H et al. Primary malignant hepatic epithelioid hemangioendothelioma: A comprehensive rewiew of the literature with emphasis on the surgical therapy. Cancer ;107:2108-21.
  • Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: A vascular tumor often mistaken for a carcinoma. Cancer ;50:970-81 . Sangro B, Inaarrairaegui M, Fernandez-Ros N. Malignant epitheloid hemangioendothelioma of the liver successfully treated with sorafenib. Rare Tumors 2012;4:e34 .
  • Caruso S, Miraglia R, Maruzelli L et al. An unusual presentation of malignant hepatic epithelioid hemangioendothelioma with left pleural and pulmonary localization.Pediatr Radiol 2008;38:1027-30
  • Ji ZF, Shen XZ, Zhang DY et al. Hepatic epithelioid hemangio endothelioma: a report of six patients. J Dig Dis 2010;11:254-8.
  • Tsuneyoshi M, Dorfman HD, Bauer TW. Epithelioid hemangio endothelioms of bone: a clinicopathologic, ultrastructural, and immunohistochemical study. Am J Surg Pathol 1986;10:754-64.
  • Langrehr JM, Petersen I, Pfitzmann R, Lopez-Hanninen E. Malignant epithelioid hemangioendothelioma of the liver. Result of surgical treatment strategies. Chirurg 2005;76:1161-7.
  • Lerut JP, Orlando G, Sempoux C et al. Hepatic hemangio endothelioma in adults: Excellent outcome following liver transplantation. Transpl Int 2004;17:202-07.
  • Ben-Haim M, Roayaise S, Ye MQ et al. Hepatic epithelioid hemangioendothelioma: Resection or transplantation, which and when? Liver Transpl Surg 1999;5:526-31.
  • Lerut JP, Orlando G, Adam R. The place of liver transplantation in the treatment of hepatic epitheloid hemangioendothelioma: report of the European liver transplant registry. Ann Surg. 2007 Dec;246(6):949-57.
Year 2016, Volume: 2 Issue: 1, 59 - 62, 01.01.2016
https://doi.org/10.5455/umj.20160121062843

Abstract

References

  • Dong K, Wnag X, Feng JL et al. Pathological characteristics of liver biopsies in eight patients with hepatic epithelioid hemangio endothelioma. Int J Clin Exp Pathol 2015;8(9): 11015-23.
  • Pregliasco AG, Wendum D, Goumard C et al. Hepatic epithelioid hemangioendothelioma. Clin Res Hepatol Gastroenterol 2015 Nov pii: S2210-7401(15)00254-5.
  • Mehrabi A, Kashfi A, Fonouni H et al. Primary malignant hepatic epithelioid hemangioendothelioma: A comprehensive rewiew of the literature with emphasis on the surgical therapy. Cancer ;107:2108-21.
  • Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: A vascular tumor often mistaken for a carcinoma. Cancer ;50:970-81 . Sangro B, Inaarrairaegui M, Fernandez-Ros N. Malignant epitheloid hemangioendothelioma of the liver successfully treated with sorafenib. Rare Tumors 2012;4:e34 .
  • Caruso S, Miraglia R, Maruzelli L et al. An unusual presentation of malignant hepatic epithelioid hemangioendothelioma with left pleural and pulmonary localization.Pediatr Radiol 2008;38:1027-30
  • Ji ZF, Shen XZ, Zhang DY et al. Hepatic epithelioid hemangio endothelioma: a report of six patients. J Dig Dis 2010;11:254-8.
  • Tsuneyoshi M, Dorfman HD, Bauer TW. Epithelioid hemangio endothelioms of bone: a clinicopathologic, ultrastructural, and immunohistochemical study. Am J Surg Pathol 1986;10:754-64.
  • Langrehr JM, Petersen I, Pfitzmann R, Lopez-Hanninen E. Malignant epithelioid hemangioendothelioma of the liver. Result of surgical treatment strategies. Chirurg 2005;76:1161-7.
  • Lerut JP, Orlando G, Sempoux C et al. Hepatic hemangio endothelioma in adults: Excellent outcome following liver transplantation. Transpl Int 2004;17:202-07.
  • Ben-Haim M, Roayaise S, Ye MQ et al. Hepatic epithelioid hemangioendothelioma: Resection or transplantation, which and when? Liver Transpl Surg 1999;5:526-31.
  • Lerut JP, Orlando G, Adam R. The place of liver transplantation in the treatment of hepatic epitheloid hemangioendothelioma: report of the European liver transplant registry. Ann Surg. 2007 Dec;246(6):949-57.
There are 11 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Erdinc Nayir

Publication Date January 1, 2016
Published in Issue Year 2016 Volume: 2 Issue: 1

Cite

Vancouver Nayir E. A Rarely Seen Hepatic Tumor: Epithelioid Hemangioendothelioma. ULUTAS MED J. 2016;2(1):59-62.