Kardiyovasküler Düzenlemede Nükleus Traktus Solitarius'un Rolü

Yıl 2011, Cilt: 30 Sayı: 1, 53 - 58, 01.06.2011

Rüveyde Köktentürk Murat Yalçın

Öz

Anahtar Kelimeler

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Kardiyovasküler Düzenlemede Nükleus Traktus Solitarius'un Rolü

Öz

Kardiyovasküler sistem, merkezi mekanizmalar tarafından sürekli olarak düzenlenmektedir. Baro- ve kemoreseptör afferentlerinin sonlandığı yer olan nükleus traktus solitarius (NTS) kardiyovasküler düzenlemede önemli katkıları olan beyin sapındaki bir nükleustur. NTS, kardiyovasküler sistem ile ilgili aldığı uyarımları, merkezi sinir sistemindeki yine kardiyovasküler düzenlemeye karışan diğer beyin bölgelerine ileterek, o beyin bölgelerinin uyarılmasını ve inhibe edilmesini sağlar ve böylece kardiyovasküler hemostasize katkıda bulunur. Bu etkilerinde, NTS’da birçok nörotransmitter ve nöromodulatör madde rol oynamaktadır. Bu derlemede baro- ve kemoreseptörlerin alınan uyarımların ilk sinaps yaptığı beyin bölgesi olan NTS’un kardiyovasküler düzenlemedeki rolü ve bu düzenlemede aracılık yapan nörotransmitter ve nöromodülatör maddeler hakkında bilgi sunulması amaçlanmıştır

Anahtar Kelimeler

Nükleus Traktus Solitarius, Kardiyovasküler Düzenleme, Baro- Kemoreseptör, Glutamat

Kaynakça

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