Research Article
BibTex RIS Cite

Kestane Balı Tıbbi Bir Baldır: Yalova Balının Antibakteriyel etkinliği, ağır metal profilive sağlık riski

Year 2021, , 82 - 89, 31.08.2021
https://doi.org/10.31797/vetbio.931144

Abstract

References

  • Altunatmaz, S.S., Tarhan, D., Aksu, F., Özsobacı, N.P, Erman, M.,Barutçu, U.M. (2018). Levels of Chromium, Copper, Iron, Magnesium, Manganese, Selenium, Zinc, Cadmium, Lead and Aluminium of honey varieties produced in Turkey. Food Science and Technology, 39:392-397. Doi :10.1590/fst.19718
  • Arıkan A.(2010). The effect of traffıc on heavy metal accumulatıon ın bee products. Ms Thesis, Gaziosmanpasa University,Graduate School of Natural and Applied Sciences , Tokat.
  • Aygün, O. (2020). Elazığ’da Üretilen Balların Bazı Toksik Ağır Metal Düzeyleri. Fırat Üniversitesi Mühendislik Bilimleri Dergisi, 32(1), 119-125.
  • Ayvaz,M Ç; Ömür,B; Ertürk, Ö; kabakçı, D (2018). Phenolic profiles, antioxidant, antimicr obial, and DNA damageinhibitory activities of chestnut honeys from Black Sea Regionof Turkey. Journal of Food Biochemistry 42:e12502
  • Bengü, A.Ş., Kutlu, M.A. (2020). Bingöl’den temin edilen ballarda ıcp-ms ile bazı temel ve toksik elementlerin analizi. Uludağ Arıcılık Dergisi, 20 (1): 1-12.
  • Bogdanov, S; Jurendıc, RS; Sieber, R; Gallmann, P (2008). Honey for Nutrition and Health: A Review. Journal of the American College of Nutrition, 27 (6): 677-689
  • Citak,D., Silici,S., Tuzen, M., Soylak, M. (2012). Determination of toxic and essential elements in sunflower honeyfrom Thrace Region, Turkey. International.Journal of Food Science and Tech, 47:107–113. doi:10.1111/j.1365-2621.2011.02814.x
  • Combarros-Fuertes, P , Estevinho, L.M., Teixeira-Santos, R., Rodrigues, A.G., Pina-Vaz, C., Fresno, J.M., Eugenia Tornadijo,M. (2020). Antibacterial Action Mechanisms of Honey: Physiological Effects of Avocado, Chestnut,and Polyfloral Honey upon Staphylococcus aureus and Escherichia coli. Molecules, 25, 1252. doi:10.3390/molecules25051252
  • Dağ,B; Sıralı,R; Tarakçı,Z (2017). Investigation Of Some Properties Of Chestnut Honey Produced In Black Sea Region Of Turkey. Batman University Journal of Life Sciences,7(2/2):118-123
  • De Oliveira RC, Queiroz SCDN, Da Luz CFP, Porto RS, Rath S. (2016). Bee pollen as a bioindicator of environmental pesticide contamination. Chemosphere,163:525–534 doi:10.1016/j.chemosphere.2016.08.022
  • Duo, D H; Dziao, S T (1937). Nachweis antibakterieller, hitze- und lichtempfindlicher Hemmungsstoffe Inhibine im Naturhonig Blatenhonig. Zeitschrift far Hygiene und lnfektionskrankheiten, 120: 155-167)
  • Dustmann, J H (1979). Antibacterial effect of honey. Apiacta, 14(1): 7-11.) EFSA (2012)Scientific Committee. Scientific panels and units in theabsence of actual measured data.
  • European Food Safety Authority Journal, 10: 2579.doi: 10.2903/j.efsa.2012.2579
  • FAO/WHO Expert Committee on Food Additives (JECFA) (2011). Safety evaluation of certain food additives andcontaminants. WHO Food Additives. 63: 605-685.
  • F.A.O. (Food and Agriculture Organization of the United Nations) (2017). Largest consumers of honey. 1–2. accessed 2020 Oct.1http://www.fao.org/3/ca4657en/ca4657en.pdf.
  • Güneş, M. E., Şahin, S., Demir, C., Borum, E., & Tosunoglu, A. (2017).Determination of phenolic compounds profile in chestnut and floralhoneys and their antioxidant and antimicrobial activities. Journal of Food Biochemistry, 41(3), 1–12.
  • Idris, Y. M. A., Mariod, A. A., Hamad, S. I. (2011).Physicochemical properties, phenolic contents and antioxidant activity of Sudanese honey. International Journal of Food Properties, 14, 450–458.
  • Kolayli, S., Can, Z., Yildiz, O, Sahin, H., Karaoglu, S.A. (2016). A comparative study of the antihyaluronidase, antiurease, antioxidant, antimicrobial and physicochemical properties of different unifloral degrees of chestnut (Castanea sativa Mill.) honeys. Journal of Enzyme Inhibition and Medicinal Chemistry, 31(S3): 96–104. https://doi.org/10.1080/14756366.2016.1209494
  • Küçük, M; Kolaylı, S; Karaoğlu,Ş; Ulus,Y,E; Baltacı,C; Candan,F (2007). Biological activities and chemical composition of three honeys of different types from Anatolia. Food Chemistry, 100(2): 526-534 Leblebici, Z.(2006). Kayseri Yöresinde Bulunan Bazı Bal Örneklerinde Ağır Metal Kirliliğinin Belirlenmesi, Yüksek Lisans Tezi, Erciyes Üniversitesi Fen Bilimleri Enstitüsü, Kayseri, 71.
  • Magna, E.K., Dabi,M., Badu, E, Owusu, P (2108). Determination of Heavy Metals and Potential Health Risk Assessment of Honey Harvested from the Tamale Metropolis of Ghana Using Atomic Absorption Spectrophotometer (AAS). Elixir Pollution, 121:51522-51525
  • McLoone, P., Tabys,D., Fyfe, L. (2020). Honey Combination Therapies for Skin and Wound Infections: A Systematic Review of the Literature. Clinical, Cosmetic and Investigational Dermatology,13: 875–888. doi: 10.2147/CCID.S282143.
  • Molan, P C; Smith, I M; Reid, G M (1988). A comparison of the antibacterial activity of some New Zealand honeys. Journal of Apicultural Research, 27(4): 252-256.
  • Naccari, C., Macaluso, A., Giangrosso, G., Naccari, F., Ferrantelli, V. (2014). Risk Assessment of Heavy Metals and Pesticides in Honey From Sicily (Italy). Journal of Food Research, 3(2), 107-117. doi:10.5539/jfr.v3n2p107
  • Nisbet, C., Guler, A., Yarim, G.F.,Cenesiz, S.,Ardalı,Y. (2013). Çevre ve flora kaynaklarının arı ürünlerinin mineral madde içerikleri ile ilişkisi. Türk Biyokimya Dergisi, 38 (4) ; 494–498.
  • Özbolat,G.,Tuli,A. (2016). Ağır metal toksisitesinin insan sağlığına etkileri. Archives Medical Review Journal, 25(4):502-521. doi:10.17827/aktd.253562
  • Perez, C., Pauli, M., & Bazerque, P. (1990). An antibiotic assay by the agar well diffusion method. Acta Biologia et Medicine Experimentalis, 15, 113–115.
  • Ru,Q.M., Feng, Q., He, H_J. (2013). Risk assessment of heavy metals in honey consumed in Zhejiang province, southeastern China. Food and Chemical Toxicology. 53: 256-262. https://doi.org/10.1016/j.fct.2012.12.015
  • Sarıkaya, A. O., Ulusoy, E., Ozturk, N., Tunçel, M., Kolayli, S. (2009).Activity and phenolic acidconstituents of chestnut (Castania sativamill.) honey and propolis. Journal of Food Biochemistry, 33, 470–481.
  • Seven,T., Can,B, Darende,B.N, Ocak,S. (2018), Hava ve Toprakta Ağır Metal Kirliliği. Ulusal Çevre Bilimleri Araştırma Dergisi, 1(2): 91-103
  • Silici,S., Uluozlu, O.Z.,Tuzen,M,Soylak,M. (2013). Honeybees and honey as monitors for heavy metal contamination near thermal power plants in Mugla,Turkey. Toxicology and Industrial Health, 32(3): 507–516. DOI: 10.1177/0748233713503393
  • Şireli, U.T., Çil, G.İ., Dikmen, B.Y, Filazi, A., Ülker, H.(2015). Detection of Metals in Different Honey Brands. Kafkas Universitesi Veteriner Fakültesi Dergisi, 21(6):915-918.
  • Tuzen ,M., Silici,S., Mendil,D., Soylak,M.(2007). Trace element levels in honeys from different regions of Turkey. Food Chemistry, 103:325–330. Doi:10.1016/j.foodchem.2006.07.053
  • Türk Gıda Kodeksi Bulaşanlar Yönetmeliği (2011). Resmi Gazete, 29.12.2011, Sayı: 28157 (3. Mükerrer), Ankara
  • USEPA. (2009). Risk-based Concentration table. Philadelphia PA. Washington DC, USA,Environmental Protection Agency
  • Yarsan, E. ,Karacal, F. , Ibrahim, I.G., Dikmen,B., Koksal, A., Das, Y.K. ( 2007). Contents of Some Metals in Honeys from Different Regions in Turkey. Bulletin of Environmental Contamination and Toxicology,79:255–258. DOI: 10.1007/s00128-007-9034-9
  • Yıldız, O., Can, A., Saral, O., Yuluğ, E., Ozturk, F., Aliyazicioglu, R.,Canpolat,S., Kolayli, S. (2013). Hepatoprotective potential of chestnut bee pollen on carbon tetrachloride-induced hepatic damages in rats. Journal of Evidence Based Complementary and Alternative Medicine, , Special Issue, Article ID 461478, 9 p. http://dx.doi.org/10.1155/2013/461478
  • Yücel, Y., Sultanoğlu, P. (2013). Characterization of Hatay honeys according to their multi-element analysis using ICP-OES combined with chemometrics. Food Chemistry, 140: 231-237. . https://doi.org/10.1016/j.foodchem.2013.02.046

Chestnut honey as a complementary medicine: determination of antibacterial activity, heavy metal residue and health risk assessment

Year 2021, , 82 - 89, 31.08.2021
https://doi.org/10.31797/vetbio.931144

Abstract

In this study, residue levels for heavy metal content and antimicrobial effects of 30 chestnut honey samples obtained from member beekeepers of Yalova Bee Association are examined. After 30 honey samples are digested under high temperature and pressure in a microwave oven, their Arsenic (As), Lead (Pb), Cadmium (Cd), Mercury (Hg) limits are determined by using ICP-OES. By using Agar gel diffusion method, 19 of the honey samples’ antibacterial activity is tested on strains of Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), E. coli O 157: H7, B.cereus (ATCC 6633), S.typhimirium (NCTC 12416) and L.monocytogenes (ATCC 7644). Arsenic, Lead, Cadmium and Mercury residue levels in all honey samples are determined to be below the designated limits by Turkish Food Codex Regulation (2011). The non-carcinogenic health risk associated with heavy metal contamination in honey is found to be very low. None of the 19 honey samples show antibacterial effect on strains of L.monocytogenes. However, at 100% honey concentration, in all 19 honey samples antibacterial effect is observed on strains of S.typhimirium, E. coli O 157: H7, except for only one honey sample; Escherichia coli and B cereus. The antibacterial activity on these bacteria is recorded to be maintained at 50% honey concentration. At 25% honey concentration, the antibacterial effect show a decline in most of the honey samples.

References

  • Altunatmaz, S.S., Tarhan, D., Aksu, F., Özsobacı, N.P, Erman, M.,Barutçu, U.M. (2018). Levels of Chromium, Copper, Iron, Magnesium, Manganese, Selenium, Zinc, Cadmium, Lead and Aluminium of honey varieties produced in Turkey. Food Science and Technology, 39:392-397. Doi :10.1590/fst.19718
  • Arıkan A.(2010). The effect of traffıc on heavy metal accumulatıon ın bee products. Ms Thesis, Gaziosmanpasa University,Graduate School of Natural and Applied Sciences , Tokat.
  • Aygün, O. (2020). Elazığ’da Üretilen Balların Bazı Toksik Ağır Metal Düzeyleri. Fırat Üniversitesi Mühendislik Bilimleri Dergisi, 32(1), 119-125.
  • Ayvaz,M Ç; Ömür,B; Ertürk, Ö; kabakçı, D (2018). Phenolic profiles, antioxidant, antimicr obial, and DNA damageinhibitory activities of chestnut honeys from Black Sea Regionof Turkey. Journal of Food Biochemistry 42:e12502
  • Bengü, A.Ş., Kutlu, M.A. (2020). Bingöl’den temin edilen ballarda ıcp-ms ile bazı temel ve toksik elementlerin analizi. Uludağ Arıcılık Dergisi, 20 (1): 1-12.
  • Bogdanov, S; Jurendıc, RS; Sieber, R; Gallmann, P (2008). Honey for Nutrition and Health: A Review. Journal of the American College of Nutrition, 27 (6): 677-689
  • Citak,D., Silici,S., Tuzen, M., Soylak, M. (2012). Determination of toxic and essential elements in sunflower honeyfrom Thrace Region, Turkey. International.Journal of Food Science and Tech, 47:107–113. doi:10.1111/j.1365-2621.2011.02814.x
  • Combarros-Fuertes, P , Estevinho, L.M., Teixeira-Santos, R., Rodrigues, A.G., Pina-Vaz, C., Fresno, J.M., Eugenia Tornadijo,M. (2020). Antibacterial Action Mechanisms of Honey: Physiological Effects of Avocado, Chestnut,and Polyfloral Honey upon Staphylococcus aureus and Escherichia coli. Molecules, 25, 1252. doi:10.3390/molecules25051252
  • Dağ,B; Sıralı,R; Tarakçı,Z (2017). Investigation Of Some Properties Of Chestnut Honey Produced In Black Sea Region Of Turkey. Batman University Journal of Life Sciences,7(2/2):118-123
  • De Oliveira RC, Queiroz SCDN, Da Luz CFP, Porto RS, Rath S. (2016). Bee pollen as a bioindicator of environmental pesticide contamination. Chemosphere,163:525–534 doi:10.1016/j.chemosphere.2016.08.022
  • Duo, D H; Dziao, S T (1937). Nachweis antibakterieller, hitze- und lichtempfindlicher Hemmungsstoffe Inhibine im Naturhonig Blatenhonig. Zeitschrift far Hygiene und lnfektionskrankheiten, 120: 155-167)
  • Dustmann, J H (1979). Antibacterial effect of honey. Apiacta, 14(1): 7-11.) EFSA (2012)Scientific Committee. Scientific panels and units in theabsence of actual measured data.
  • European Food Safety Authority Journal, 10: 2579.doi: 10.2903/j.efsa.2012.2579
  • FAO/WHO Expert Committee on Food Additives (JECFA) (2011). Safety evaluation of certain food additives andcontaminants. WHO Food Additives. 63: 605-685.
  • F.A.O. (Food and Agriculture Organization of the United Nations) (2017). Largest consumers of honey. 1–2. accessed 2020 Oct.1http://www.fao.org/3/ca4657en/ca4657en.pdf.
  • Güneş, M. E., Şahin, S., Demir, C., Borum, E., & Tosunoglu, A. (2017).Determination of phenolic compounds profile in chestnut and floralhoneys and their antioxidant and antimicrobial activities. Journal of Food Biochemistry, 41(3), 1–12.
  • Idris, Y. M. A., Mariod, A. A., Hamad, S. I. (2011).Physicochemical properties, phenolic contents and antioxidant activity of Sudanese honey. International Journal of Food Properties, 14, 450–458.
  • Kolayli, S., Can, Z., Yildiz, O, Sahin, H., Karaoglu, S.A. (2016). A comparative study of the antihyaluronidase, antiurease, antioxidant, antimicrobial and physicochemical properties of different unifloral degrees of chestnut (Castanea sativa Mill.) honeys. Journal of Enzyme Inhibition and Medicinal Chemistry, 31(S3): 96–104. https://doi.org/10.1080/14756366.2016.1209494
  • Küçük, M; Kolaylı, S; Karaoğlu,Ş; Ulus,Y,E; Baltacı,C; Candan,F (2007). Biological activities and chemical composition of three honeys of different types from Anatolia. Food Chemistry, 100(2): 526-534 Leblebici, Z.(2006). Kayseri Yöresinde Bulunan Bazı Bal Örneklerinde Ağır Metal Kirliliğinin Belirlenmesi, Yüksek Lisans Tezi, Erciyes Üniversitesi Fen Bilimleri Enstitüsü, Kayseri, 71.
  • Magna, E.K., Dabi,M., Badu, E, Owusu, P (2108). Determination of Heavy Metals and Potential Health Risk Assessment of Honey Harvested from the Tamale Metropolis of Ghana Using Atomic Absorption Spectrophotometer (AAS). Elixir Pollution, 121:51522-51525
  • McLoone, P., Tabys,D., Fyfe, L. (2020). Honey Combination Therapies for Skin and Wound Infections: A Systematic Review of the Literature. Clinical, Cosmetic and Investigational Dermatology,13: 875–888. doi: 10.2147/CCID.S282143.
  • Molan, P C; Smith, I M; Reid, G M (1988). A comparison of the antibacterial activity of some New Zealand honeys. Journal of Apicultural Research, 27(4): 252-256.
  • Naccari, C., Macaluso, A., Giangrosso, G., Naccari, F., Ferrantelli, V. (2014). Risk Assessment of Heavy Metals and Pesticides in Honey From Sicily (Italy). Journal of Food Research, 3(2), 107-117. doi:10.5539/jfr.v3n2p107
  • Nisbet, C., Guler, A., Yarim, G.F.,Cenesiz, S.,Ardalı,Y. (2013). Çevre ve flora kaynaklarının arı ürünlerinin mineral madde içerikleri ile ilişkisi. Türk Biyokimya Dergisi, 38 (4) ; 494–498.
  • Özbolat,G.,Tuli,A. (2016). Ağır metal toksisitesinin insan sağlığına etkileri. Archives Medical Review Journal, 25(4):502-521. doi:10.17827/aktd.253562
  • Perez, C., Pauli, M., & Bazerque, P. (1990). An antibiotic assay by the agar well diffusion method. Acta Biologia et Medicine Experimentalis, 15, 113–115.
  • Ru,Q.M., Feng, Q., He, H_J. (2013). Risk assessment of heavy metals in honey consumed in Zhejiang province, southeastern China. Food and Chemical Toxicology. 53: 256-262. https://doi.org/10.1016/j.fct.2012.12.015
  • Sarıkaya, A. O., Ulusoy, E., Ozturk, N., Tunçel, M., Kolayli, S. (2009).Activity and phenolic acidconstituents of chestnut (Castania sativamill.) honey and propolis. Journal of Food Biochemistry, 33, 470–481.
  • Seven,T., Can,B, Darende,B.N, Ocak,S. (2018), Hava ve Toprakta Ağır Metal Kirliliği. Ulusal Çevre Bilimleri Araştırma Dergisi, 1(2): 91-103
  • Silici,S., Uluozlu, O.Z.,Tuzen,M,Soylak,M. (2013). Honeybees and honey as monitors for heavy metal contamination near thermal power plants in Mugla,Turkey. Toxicology and Industrial Health, 32(3): 507–516. DOI: 10.1177/0748233713503393
  • Şireli, U.T., Çil, G.İ., Dikmen, B.Y, Filazi, A., Ülker, H.(2015). Detection of Metals in Different Honey Brands. Kafkas Universitesi Veteriner Fakültesi Dergisi, 21(6):915-918.
  • Tuzen ,M., Silici,S., Mendil,D., Soylak,M.(2007). Trace element levels in honeys from different regions of Turkey. Food Chemistry, 103:325–330. Doi:10.1016/j.foodchem.2006.07.053
  • Türk Gıda Kodeksi Bulaşanlar Yönetmeliği (2011). Resmi Gazete, 29.12.2011, Sayı: 28157 (3. Mükerrer), Ankara
  • USEPA. (2009). Risk-based Concentration table. Philadelphia PA. Washington DC, USA,Environmental Protection Agency
  • Yarsan, E. ,Karacal, F. , Ibrahim, I.G., Dikmen,B., Koksal, A., Das, Y.K. ( 2007). Contents of Some Metals in Honeys from Different Regions in Turkey. Bulletin of Environmental Contamination and Toxicology,79:255–258. DOI: 10.1007/s00128-007-9034-9
  • Yıldız, O., Can, A., Saral, O., Yuluğ, E., Ozturk, F., Aliyazicioglu, R.,Canpolat,S., Kolayli, S. (2013). Hepatoprotective potential of chestnut bee pollen on carbon tetrachloride-induced hepatic damages in rats. Journal of Evidence Based Complementary and Alternative Medicine, , Special Issue, Article ID 461478, 9 p. http://dx.doi.org/10.1155/2013/461478
  • Yücel, Y., Sultanoğlu, P. (2013). Characterization of Hatay honeys according to their multi-element analysis using ICP-OES combined with chemometrics. Food Chemistry, 140: 231-237. . https://doi.org/10.1016/j.foodchem.2013.02.046
There are 37 citations in total.

Details

Primary Language English
Subjects Veterinary Sciences, Veterinary Surgery
Journal Section Research Articles
Authors

Mesut Ertan Güneş 0000-0002-9347-8307

Publication Date August 31, 2021
Submission Date May 1, 2021
Acceptance Date July 28, 2021
Published in Issue Year 2021

Cite

APA Güneş, M. E. (2021). Chestnut honey as a complementary medicine: determination of antibacterial activity, heavy metal residue and health risk assessment. Journal of Advances in VetBio Science and Techniques, 6(2), 82-89. https://doi.org/10.31797/vetbio.931144

22563   CABI-Logo_NEW_accessible.jpg   logo_world_of_journals_no_margin.png  download download   download   download        download