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A contribution to the study of crystalluria: significance in the diagnosis of metabolic and renal diseases

Year 2020, Volume: 5 Issue: 2, 81 - 89, 31.08.2020
https://doi.org/10.31797/vetbio.735104

Abstract

The study of crystalluria is of great importance for the detection of substances of endogenous or exogenous origin that are present inthe urine, to a greater or lesser extent. Urinary sediment crystals can provide valuable answers for the assessment of therapeutic efficacy, as well as congenital and/or acquired pathophysiological conditions. The nature of the observed crystals informs the clinician of the biochemical irregularity of the urine.
Crystalluria is of clinical significance only if it has been studied under good test conditions (sample selection, time and storage conditions). Crystalluria interpretations are performed on the basis of the urinary pH determined with statistically significant reliability. When studying crystalluria by light microscopy, it is necessary to provide light polarization or bidirectional illuminationin order to reduce the risk of diagnostic error.

References

  • Abraham, P.A., Smith, C.L. (1987). Evaluation of factors involved in calcium stone formation. Miner Electrolyte Metab 13, 201–8.
  • Azoury, R., Robertson, W.G., Garside, J. (1987). Observations on in vitro and in vivo calcium oxalate crystalluria in primary calcium stone formers and normal subjects. Br J Urol 59(3), 211-213.
  • Bader, C.A., Chevalier, A., Hennequin, C., Jungers, P., Daudon, M. (1994). Methodological aspects of spontaneous crystalluria studies in calcium stone formers. Scanning Microsc 8, 215–32.
  • Bush, B.M. (1998). Interpretation of Laboratory Results for Small Animal Clinicians. 5th Ed., Cornwall: MPG Books Ltd, Bodmin.
  • Cairo, M.S., Bishop, M. (2004). Tumour lysis syndrome: new therapeutic strategies and classification. Br J Haematol 127, 3–11.
  • Daudon, M., Frochot, V. (2015). Crystalluria. De Grutyer-Clin Chem Lab Med. 53(Suppl), S1479–S1487. DOI 10.1515/cclm-2015-0860
  • Daudon, M., Hennequin, C., Bader, C., Jungers, P., Lacour, B., Drueke, T. (1995). Inhibitors of crystallization. Adv Nephrol 24,167–216.
  • Daudon, M., Jungers, P., Lacour, B. (2004). Intéręt clinique de l’étude de la cristallurie. Ann Biol Cli 62, 379–93.
  • Daudon, M., Jungers, P. (2004). Clinical value of crystalluria and quantitative morphoconstitutional analysis of urinary calculi. Nephron Physiol 98, 31–6.
  • Daudon, M., Marfisi, C., Lacour, B., Bader, C. (1991). Investigation of urinary crystals by Fourier transform infared microscopy. Clin Chem 37, 83–7.
  • Daudon, M. (2015). Cristallurie. EMC – Néphrologie 10, 1–15.
  • Davis, K.U., Grindem, C.B. (2015). What is your diagnosis? Urine crystals from a dog. Clin Pathol 44(2), 331–332. DOI:10.1111/vcp.12233
  • Elliot, J.S., Rabinowitz, I.N. (1980). Calcium Oxalate Crystalluria: Crystal Size in Urine. J Urol, 123, 324–7.
  • Fogazzi, G.B., Garigali, G. (2013). The urinary sediment by sedIMAX. A new approach to urinary sediment examination. Milano: Elsevier, 2013.
  • Fogazzi, G.B., Ponticelli, C., Ritz, E. (2000). The urinary sediment: an integrated view. 2nd ed. Oxford: Oxford University Press.
  • Fogazzi, G.B. (1996). Crystalluria: a neglected aspect of urinary sediment analysis. Nephrol Dial Transplant 11, 379-87.
  • Fogazzi, G.B. (1987). The urinary sediment an integrated view 3rd ed. Milano: Elsevier, 2010.formers and normal subjects. Br J Urol 59, 211–3.
  • Graff, L. A. (1982). Handbook of routine urinalysis. Toronto: JB Lippincott. https://doi.org/10.1016/S0022-5347(17)55918-2
  • Katica, M. (2020). Značaj mikroskopske analize organskog mokraćnog sedimenta u veterinarskoj praksi. Veterinaria 69(1), 15-22.
  • Katica, M., Ahmed, N.S. Salkić, A., Mukača, A., Bašić, A., Dervišević, E., (2019). The role of organic urine sediment analysis in the monitoring of renal disease. J. Adv. VetBio. Sci. Tech 4(1), 40-50.
  • Kok, D.J., Papapoulos, S.E., Bijvoet, O.L. (1986). Excessive crystal agglomeration with low citrate excretion in recurrent stone-formers. Lancet 1, 1056–1058.
  • Kouri, T., Fogazzi, G., Gant, V., Hallander, H., Hofmann, W.,Guder, W.G. (2000). European urinalysis guidelines. ECLM -European Urinalysis Group. Scand J Clin Lab Invest 60, Suppl 231, 1-96.
  • Meichner, K., Olsson, S.A., Stewart, D.R., Musser, M.L., Grindem, C.B. (2015). What is your diagnosis? Urine crystals in a dog. Vet Clin Pathol. 44(4), 613–614. DOI:10.1111/vcp.12296
  • Okafor, C.C., Pearl, D.L., Blois, S.L., Lefebvre, S.L., Yang, M., Lund, E.M., Dewey, C.E. (2018). Factors associated with hematuric struvite crystalluria in cats. Journal of Feline Medicine and Surgery 1–9, doi: 10.1177/1098612X18809176
  • Osborne, C.A., Lulich, J.P., Kruger, J.M., et al. (2009). Analysis of 451,891 canine uroliths, feline uroliths, and feline urethral plugs from 1981 to 2007: perspectives from the Minnesota Urolith Center. Vet Clin North Am Small Anim Pract 39, 183–197.
  • Osborne, C.A., Lulich, J.P., Swanson, L.L., Albasan, H. (2008). Drug-induced urolithiasis. Vet Clin Small Anim 39, 55–63.
  • Osborne, C.A., Stevens, J.B. (1999). Urinalysis: A Clinical Guide to Compassionate Patient Care. Shawnee Mission, KS: Bayer.
  • Rivara, C.M., Johnson, C.R., Lulich, J.P., Osborne, C.A., Murtaugh, M. (2013). The effect of disease on the urinary purine metabolite concentrations in dogs. Vet Rec 173, 219–224.
  • Rizzi, T.E., Valenciano, A., Bowles, M., Cowell, R., Tyler, R., De Nicola, D.B. (2017). Atlas of Canine and Feline Urinalysis. 1st ed. USA: John Wiley & Sons, Inc. Published. doi:10.1002/9781119365693.ch4
  • Robert, M., Boularan, A.M., Delbos, O., Guiter, J., Descomps, B. (1998). Study of Calcium Oxalate Crystalluria on Renal and Vesical Urines in Stone Formers and Normal Subjects. Urol Int 60, 41-46.
  • Ryall, R.L., Harnett, R.M., Marshall, V.R. (1981). The effect of urine pyrophosphate, citrate, magnesium and glycosaminoglycans on the growth and aggregation of calcium oxalate crystals in vitro. Clin Chim Acta 112, 349–56.
  • Sikirica, M., Bobetić-Vranić, T., Flegar-Meštrić, Z., Kardum-Skelin, I., Dubravka, Juretić. D. (2002). Standardized Analysis of Urine Supravitally Stained Urine Sediment. Biochemia Medica 12(3–4), 57-72.
  • Sturgess, C.P., Hesford, A., Owen, H., Privett, R. (2001). An Investigation into the Effects of Storage on the Diagnosis of Crystalluria in Cats. Journal of Feline Medicine and Surgery 3, 81–85. doi:10.1053/jfms.2001.0118.
  • Werness, P.G., Bergert, J.H., Smith, L.H. (1981). Crystalluria. J Crystal Growth 53, 166–81.
  • Wilcox, W.R., Khalaf, A., Weinberger, A., Kippen, I., Klinenberg, JR. (1972). Solubility of uric acid and monosodium urate. Med Biol Eng 10, 522–31.
Year 2020, Volume: 5 Issue: 2, 81 - 89, 31.08.2020
https://doi.org/10.31797/vetbio.735104

Abstract

References

  • Abraham, P.A., Smith, C.L. (1987). Evaluation of factors involved in calcium stone formation. Miner Electrolyte Metab 13, 201–8.
  • Azoury, R., Robertson, W.G., Garside, J. (1987). Observations on in vitro and in vivo calcium oxalate crystalluria in primary calcium stone formers and normal subjects. Br J Urol 59(3), 211-213.
  • Bader, C.A., Chevalier, A., Hennequin, C., Jungers, P., Daudon, M. (1994). Methodological aspects of spontaneous crystalluria studies in calcium stone formers. Scanning Microsc 8, 215–32.
  • Bush, B.M. (1998). Interpretation of Laboratory Results for Small Animal Clinicians. 5th Ed., Cornwall: MPG Books Ltd, Bodmin.
  • Cairo, M.S., Bishop, M. (2004). Tumour lysis syndrome: new therapeutic strategies and classification. Br J Haematol 127, 3–11.
  • Daudon, M., Frochot, V. (2015). Crystalluria. De Grutyer-Clin Chem Lab Med. 53(Suppl), S1479–S1487. DOI 10.1515/cclm-2015-0860
  • Daudon, M., Hennequin, C., Bader, C., Jungers, P., Lacour, B., Drueke, T. (1995). Inhibitors of crystallization. Adv Nephrol 24,167–216.
  • Daudon, M., Jungers, P., Lacour, B. (2004). Intéręt clinique de l’étude de la cristallurie. Ann Biol Cli 62, 379–93.
  • Daudon, M., Jungers, P. (2004). Clinical value of crystalluria and quantitative morphoconstitutional analysis of urinary calculi. Nephron Physiol 98, 31–6.
  • Daudon, M., Marfisi, C., Lacour, B., Bader, C. (1991). Investigation of urinary crystals by Fourier transform infared microscopy. Clin Chem 37, 83–7.
  • Daudon, M. (2015). Cristallurie. EMC – Néphrologie 10, 1–15.
  • Davis, K.U., Grindem, C.B. (2015). What is your diagnosis? Urine crystals from a dog. Clin Pathol 44(2), 331–332. DOI:10.1111/vcp.12233
  • Elliot, J.S., Rabinowitz, I.N. (1980). Calcium Oxalate Crystalluria: Crystal Size in Urine. J Urol, 123, 324–7.
  • Fogazzi, G.B., Garigali, G. (2013). The urinary sediment by sedIMAX. A new approach to urinary sediment examination. Milano: Elsevier, 2013.
  • Fogazzi, G.B., Ponticelli, C., Ritz, E. (2000). The urinary sediment: an integrated view. 2nd ed. Oxford: Oxford University Press.
  • Fogazzi, G.B. (1996). Crystalluria: a neglected aspect of urinary sediment analysis. Nephrol Dial Transplant 11, 379-87.
  • Fogazzi, G.B. (1987). The urinary sediment an integrated view 3rd ed. Milano: Elsevier, 2010.formers and normal subjects. Br J Urol 59, 211–3.
  • Graff, L. A. (1982). Handbook of routine urinalysis. Toronto: JB Lippincott. https://doi.org/10.1016/S0022-5347(17)55918-2
  • Katica, M. (2020). Značaj mikroskopske analize organskog mokraćnog sedimenta u veterinarskoj praksi. Veterinaria 69(1), 15-22.
  • Katica, M., Ahmed, N.S. Salkić, A., Mukača, A., Bašić, A., Dervišević, E., (2019). The role of organic urine sediment analysis in the monitoring of renal disease. J. Adv. VetBio. Sci. Tech 4(1), 40-50.
  • Kok, D.J., Papapoulos, S.E., Bijvoet, O.L. (1986). Excessive crystal agglomeration with low citrate excretion in recurrent stone-formers. Lancet 1, 1056–1058.
  • Kouri, T., Fogazzi, G., Gant, V., Hallander, H., Hofmann, W.,Guder, W.G. (2000). European urinalysis guidelines. ECLM -European Urinalysis Group. Scand J Clin Lab Invest 60, Suppl 231, 1-96.
  • Meichner, K., Olsson, S.A., Stewart, D.R., Musser, M.L., Grindem, C.B. (2015). What is your diagnosis? Urine crystals in a dog. Vet Clin Pathol. 44(4), 613–614. DOI:10.1111/vcp.12296
  • Okafor, C.C., Pearl, D.L., Blois, S.L., Lefebvre, S.L., Yang, M., Lund, E.M., Dewey, C.E. (2018). Factors associated with hematuric struvite crystalluria in cats. Journal of Feline Medicine and Surgery 1–9, doi: 10.1177/1098612X18809176
  • Osborne, C.A., Lulich, J.P., Kruger, J.M., et al. (2009). Analysis of 451,891 canine uroliths, feline uroliths, and feline urethral plugs from 1981 to 2007: perspectives from the Minnesota Urolith Center. Vet Clin North Am Small Anim Pract 39, 183–197.
  • Osborne, C.A., Lulich, J.P., Swanson, L.L., Albasan, H. (2008). Drug-induced urolithiasis. Vet Clin Small Anim 39, 55–63.
  • Osborne, C.A., Stevens, J.B. (1999). Urinalysis: A Clinical Guide to Compassionate Patient Care. Shawnee Mission, KS: Bayer.
  • Rivara, C.M., Johnson, C.R., Lulich, J.P., Osborne, C.A., Murtaugh, M. (2013). The effect of disease on the urinary purine metabolite concentrations in dogs. Vet Rec 173, 219–224.
  • Rizzi, T.E., Valenciano, A., Bowles, M., Cowell, R., Tyler, R., De Nicola, D.B. (2017). Atlas of Canine and Feline Urinalysis. 1st ed. USA: John Wiley & Sons, Inc. Published. doi:10.1002/9781119365693.ch4
  • Robert, M., Boularan, A.M., Delbos, O., Guiter, J., Descomps, B. (1998). Study of Calcium Oxalate Crystalluria on Renal and Vesical Urines in Stone Formers and Normal Subjects. Urol Int 60, 41-46.
  • Ryall, R.L., Harnett, R.M., Marshall, V.R. (1981). The effect of urine pyrophosphate, citrate, magnesium and glycosaminoglycans on the growth and aggregation of calcium oxalate crystals in vitro. Clin Chim Acta 112, 349–56.
  • Sikirica, M., Bobetić-Vranić, T., Flegar-Meštrić, Z., Kardum-Skelin, I., Dubravka, Juretić. D. (2002). Standardized Analysis of Urine Supravitally Stained Urine Sediment. Biochemia Medica 12(3–4), 57-72.
  • Sturgess, C.P., Hesford, A., Owen, H., Privett, R. (2001). An Investigation into the Effects of Storage on the Diagnosis of Crystalluria in Cats. Journal of Feline Medicine and Surgery 3, 81–85. doi:10.1053/jfms.2001.0118.
  • Werness, P.G., Bergert, J.H., Smith, L.H. (1981). Crystalluria. J Crystal Growth 53, 166–81.
  • Wilcox, W.R., Khalaf, A., Weinberger, A., Kippen, I., Klinenberg, JR. (1972). Solubility of uric acid and monosodium urate. Med Biol Eng 10, 522–31.
There are 35 citations in total.

Details

Primary Language English
Subjects Veterinary Sciences
Journal Section Erratum
Authors

Muhamed Katica 0000-0002-8184-0065

Nasreldin Hassan Ahmed This is me 0000-0002-5728-7052

Nedžad Gradaščević This is me 0000-0003-4759-3192

Alen Salkić This is me 0000-0002-5728-7052

Emina Dervišević This is me 0000-0002-5728-7052

Publication Date August 31, 2020
Submission Date May 10, 2020
Acceptance Date August 28, 2020
Published in Issue Year 2020 Volume: 5 Issue: 2

Cite

APA Katica, M., Hassan Ahmed, N., Gradaščević, N., Salkić, A., et al. (2020). A contribution to the study of crystalluria: significance in the diagnosis of metabolic and renal diseases. Journal of Advances in VetBio Science and Techniques, 5(2), 81-89. https://doi.org/10.31797/vetbio.735104

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