VETERİNER HEKİMLİKTE ETİKET DIŞI İLAÇ KULLANIMI: ANTİMİKROBİYAL İLAÇLAR

Year 2020, Volume: 11 Issue: 3, 134 - 150, 30.12.2020

Ender Yarsan , Sinem Pehlivan

https://doi.org/10.38137/vetfarmatoksbulten.803682

Cited By: 1

Abstract

Etiket dışı ya da endikasyon dışı ilaç kullanımı kavramı, bir ürünün, prospektüsünde veya etiketinde belirtildiğinden farklı şekilde uygulanması olarak tanımlanabilir. Bu tanımdan hareketle hekim; ilacın prospektüs bilgileri dışında olacak şekilde, farklı bir türde, farklı bir doz aralığında, dozaj rejiminde ve süreyle ilaç uygulaması yapabilir. Bu durum gerek ülkemizde gerekse uluslararası alanda kabul gören bir yaklaşımdır. Veteriner hekimliği ve beşeri hekimlikte yasal mevzuat ile çerçevesi çizilmiştir. Ancak bu uygulama ile sorumluluk tümüyle hekime yüklenmektedir. Dolayısıyla hekim bu türden bir uygulama yapacaksa mutlaka bir onam formu/belgesi almalı, hasta sahibine konuyla ilgili bilgi vermelidir. Antimikrobiyal ilaçlar bu uygulamanın önemli bir parçasını oluşturur. Olası bir hata ya da yanlış kullanım, hasta yönüyle olduğu kadar halk sağlığı yönüyle de “antimikrobiyal direnç” ve “kalıntı” gibi olumsuzluklara neden olabilir. Bu makale kapsamında etiket dışı ilaç kullanımı konusunda temel bilgiler sunuldu ve konu özellikle antimikrobiyal ilaçlar yönüyle tür bazında değerlendirildi.

Keywords

Antibakteriyel, Etiket dışı, İlaç, Veteriner Hekimlik

OFF-LABEL DRUG USE IN VETERINARY MEDICINE: ANTIMICROBIAL DRUGS

Abstract

The concept of off-label or off-indication drug use can be defined as the administration of a product used in a different way than it is prescribed in its prospectus or label. Based on this definition, physicians can administrate drugs in; different species, a different dosage range, dosage regime and periods. This is an approach which is accepted by both our country and globally. The framework of this practice is drawn by the legal legislation in human medicine and veterinary medicine. However, with this approach, the responsibility belongs to the physician entirely. Therefore, the physician must inform the animal owner and obtain a consent form if such an application is to be administered Antimicrobial drugs are major part of this application. A possible mistake or misuse may cause undesirable effects in terms of public health as well as the patient such as antimicrobial resistance and residue. In this article, basic information about the use of off-label drug was given and the subject was evaluated according to species, especially in terms of antimicrobial drugs.

Keywords

Antimicrobial, Drug, Off-label, Veterinary Medicine

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