Araştırma Makalesi
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The Mathematical Outcome of The IVF, Including Early Cleavage

Yıl 2023, Cilt: 4 Sayı: 3, 110 - 116, 08.08.2023

Öz

Aim: In this manuscript, the examination of independent factors for the success of IVF (In Vitro Fertilization) was aimed
to be conducted.
Material and Methods: Hormones, including Anti-Mullerian
Hormone (AMH), Follicle Stimulating Hormone(FSH), the
growth stages of the oocyte that turns into an embryo (total
fertilized oocyte, early cleavage, etc.), the medical adjustments
were included. Our dependent factor, the success of fertilization, was categorized into two groups; in other words, binary
logistic regression for pregnancy success was examined.
Results: For the statistical significance of our study, Omnibus
Tests of Model Coefficients (p-value=0,008) and Hosmer and
Lemeshow tests (p-value=0,462) were conducted. Our model
was successful through statistical meaningfulness. With a ChiSquare test with a p-value of close to zero, women’s age groups
were proven different for groups below and over the age of 35
for InVitro Fertilization (IVF)
Discussion and conclusion: Study shows Early Segmentation
increases the chances of pregnancy; In contrast, the woman's
age and FSH reduce the likelihood of pregnancy.

Kaynakça

  • 1. Zhang J, Wang C, Zhang H, Zhou Y. Sequential cleavage and blastocyst embryo transfer and IVF outcomes: a systematic review. Reprod Biol Endocrinol. 2021 Sep 14;19(1):142. doi: 10.1186/s12958-021-00824-y. PMID: 34521412; PMCID: PMC8439041.
  • 2. Lundin K, Bergh C, & Hardarson T. Early embryo cleavage is a strong indicator of embryo quality in human IVF. Hum Reprod. 2001 Dec; 16(12):2652-7. doi: 10.1093/ humrep/16.12.2652. PMID: 11726590.
  • 3. Van Marion ES, Baart EB, Santos M, van Duijn L, van Santbrink EJP, Steegers-Theunissen RPM, Laven JSE, & Eijkemans MJC. Using the embryo-uterus statistical model to predict pregnancy chances by using cleavage stage morphokinetics and female age: two centre-specific prediction models and mutual validation. Reprod Biol Endocrinol. 2023 Mar 27; 21(1):31. doi: 10.1186/s12958-023-01076-8. PMID: 36973721; PMCID: PMC10041771.
  • 4. FISHER, R. A. “STUDENT”.1939, Annals of Eugenics, 9: 1–9. doi:10.1111/j.1469- 1809.1939.tb02192.x
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  • 9. Lekamge D. N., Barry M., Kolo M., Lane M., Gilchrist R. B., Tremellen K. P. Anti-Mül-lerian hormone as a predictor of IVF outcome. Reproductive Biomedicine Online; 2007; 14(5): 602-610.
  • 10. Bos-Mikich A., Mattos A. L. G., Ferrari A. N. Early cleavage of human embryos: an effective method for predicting successful IVF/ICSI outcome. Human Reproduction. 2001; 16(12): 2658-2661.
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  • 13. Palomba, S., Daolio, J., & La Sala, G. B. Oocyte competence in women with polycystic ovary syndrome. Trends in Endocrinology & Metabolism. 2016; 28(3): 186 - 198
  • 14. Levin, D., Jun S. H., Dahan, M. H. Predicting pregnancy in women undergoing in-vitro fertilization with basal serum follicle stimulating hormone levels between 10.0 and 11.9 IU/L. Journal of the Turkish German Gynecological Association, 2015; 16(1): 5-10
  • 15. Klein N. A., Illingworth P. J., Groome N. P., McNeilly A. S., Battaglia D. E., Soules, M. R. Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: a study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles. The Journal of Clinical Endocrinology & Metabolism, 1996; 81(7): 2742-2745.
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  • 18. Yao L., Zhang W., Li, H., & Lin W. The role of serum AMH and FF AMH in predicting pregnancy outcome in the fresh cycle of IVF/ICSI: a meta-analysis. International Journal of Clinical and Experimental Medicine. 2015; 8(2): 1755-1767.
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  • 22. Lee M.J., Lee R. K.K., Lin M.H., Hwu Y.M. Cleavage speed and implantation potential of early-cleavage embryos in IVF or ICSI cycles”. Journal of Assisted Reproduction and Genetics, 2012; 29(8): 745–750.
Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri (Diğer)
Bölüm Araştırma Makaleleri
Yazarlar

Simge Or Bu kişi benim 0000-0002-4607-7199

Pelin Öçal Bu kişi benim 0000-0002-7531-5942

Nurten Dayıoglu Bu kişi benim 0000-0002-4598-4678

Tülay İrez Bu kişi benim

Yayımlanma Tarihi 8 Ağustos 2023
Gönderilme Tarihi 7 Nisan 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 4 Sayı: 3

Kaynak Göster

AMA Or S, Öçal P, Dayıoglu N, İrez T. The Mathematical Outcome of The IVF, Including Early Cleavage. JMS. Ağustos 2023;4(3):110-116.