Investigation of the Effects of Biomaterials Used in Cranioplasty on Radiotherapy Dose Through the Monte Carlo Method

Yıl 2024, Cilt: 5 Sayı: 1, 16 - 21, 30.01.2024

Meryem Cansu Şahin , Gökçe Nur Gündüz , Kaan Ciyerci , Ali Teke , Batuhan Yıldız

Öz

Aim: The gold standard in the treatment of brain tumors is
radiotherapy and chemotherapy after surgery. Radiotherapy
with high-energy ionizing radiation after surgery has an important place in the treatment of brain tumors. Implants with
a high atomic number exhibit strong radiation attenuation and
scattering properties that could potentially compromise the
delivery of radiation therapy by distorting the dose distribution in and around the implant volume, complicating treatment planning in radiotherapy. In this study, it was aimed to
investigate the interaction of biomaterials used in cranioplasty
applications with X-rays used in radiotherapy using a GAMOS
simulation.
Methods: The head phantom defined in the GAMOS simulation includes, from left to right, 0.2 cm of skin, 0.3 cm of soft
tissue, 1 cm of skull, 12 cm of brain, 1 cm of skull, 0.3 cm of soft
tissue, and finally, 0.2 cm of skin. In order to observe the effect of different biomaterials, selected biomaterials (CCM alloy,
stainless steel, alumina, NiTi alloy, titanium, PEEK, PMMA,
and PTFE) were defined instead of a 1 cm skull. In this configuration, the brain tissue is also defined as the detector to absorb
energy.
Results: Cortical bone has a density of 1.920 g/cm3
and the
dose taken by the brain tissue was found to be 4,843 Gy. It was
observed that the dose value absorbed in the brain tissue decreased with the increase in the densities of the biomaterials
used in cranioplasty. Dose results for PTFE and PEEK biomaterials were found to be close to bone tissue.
Conclusion: As a result, PEEK and PMMA biomaterials,
whose densities are very close to those of bone tissue, showed
similarity to bone tissue in terms of radiotherapy dose distribution.

Anahtar Kelimeler

biomaterials, cranioplasty, radiotherapy, GAMOS

Kaynakça

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