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Hematüri şikayetiyle gelen hastada prostat kanserinin nadir bir varyantı olan prostat duktal adenokarsinomu tanısı

Year 2012, Volume: 7 Issue: 1, 66 - 69, 01.01.2012

Abstract

Prostatın duktal adenokarsinomu prostat karsinomunun nadir bir histolojik alt tipidir. Prostat kanserlerinin % 0.2’sinde görülür ve kötü prognoza sahiptir. Olgumuz, 78 yaşında erkek hasta, hematüri şikayetiyle kliniğimize başvurdu. Endoskopide verru montanum üzerinde papiller üretral kitle gösterildi. Transüretral rezeksiyon uygulandı. Histopatolojik ve immunhistokimyasal inceleme sonucunda prostat duktal adenokarsinomu tanısı konuldu. Hastaya hormonoterapi ve radyoterapi tedavisi uygulandı ve olumlu cevap alındı. Prostat duktal adenokarsinomu nadir görülen bir tümördür. Tümör kötü prognozlu olup agresif tedavi gerektirebilir. Bu nedenle erken tanı ve tedavi önem kazanmaktadır. Prostat kanserlerinin ayırıcı tanısında duktal adenokarsinomlar mutlaka akılda tutulmalıdır

References

  • Yang XJ, Helpap B, Samaratunga H. Ductaladenocarcinoma. In: Tumours of the urinary system and male genital organs. Eble NJ, Sauter G, Epstein JI, Sesterhenn IA (Editors). IARC Pres Lyon. 2004: 3; 199- 202.
  • Tu WH, Jensen K, Freiha F, Liao JC. A Case of Prostatic Ade- nocarcinoma Recurrence Presenting As Ductal Carcinoma of the Prostate. Nat Clin Pract Urol 2008; 5 (1): 55-58.
  • Eade TN, Al-Saleem T, Horwitz EM, et al. Role of Radiothe- rapy in Ductal (Endometrioid) Carcinoma of the Prostate. Cancer 2007; 109: 2011-2015.
  • Tulunay Ö, Orhan D, Baltacı S, Göğüş Ç, Müftüoğlu YZ. Pros- tatic Ductal Adenocarcinoma Showing Bcl-2 Expression. Int J Urol 2004; 11: 805-808.
  • Vale JA, Patel A, Ball AJ, et al. Endometrioid Carcinoma of the Prostate: A Misnomer? J R Soc Med 1992; 85: 394-396.
  • Guo CC, Epstein JI. Intraductal Carcinoma of the Prostate on Needle Biopsy: Histologic Features and Clinical Significance. Mod Pathol 2006; 19: 1528- 1535.
  • Melicow MM, Pachter MR. Endometrial Carcinoma of Pros- tatic Utricle (uterus masculinus). Cancer 1967; 20: 1715-1722.
  • Epstein JI, Allsbrook WC, Amin MB, Egevad LL. The 2005 In- ternational Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. Am J Surg Pathol 2005; 29: 1228-1242.
  • Christensen WN, Steinberg G, Walsh PC, et al. Prostatic duct adenocarcinoma. Findings at radical prostatectomy. Cancer 1999; 67: 2118–24.
  • Brinker DA, Potter SR, Epstein JI. Ductal adenocarcinoma of the prostate diagnosed on needle biopsy: correlation with cli- nical and radical prostatectomy findings and progression. Am J Sug Pathol 1999; 23: 1471–9

Diagnosis of ductal adenocarcinoma of the prostate is a rare variant of prostate cancer from the patients with complaints of hematuria

Year 2012, Volume: 7 Issue: 1, 66 - 69, 01.01.2012

Abstract

Ductal carcinoma of the prostate is a rare histologic subtype of prostate carcinoma. It represents 0.2% of all prostate cancers and is associated with a poor prognosis. Our case , 78 years old man, applied our clinic with complaint of of hematuria. Papillary urethral mass was shown on verru montanum by endoscopy. We performed transurethral resection. Diagnosis of prostate ductal adenocarsinoma was diagnosed by the result of histopatologic and immunohistochemical examination. The patient was treated by hormonotherapy and radiotherapy and received a positive response.The ductal adenocarcinoma of prostate is a rarely seen tumor. The tumors have poor prognoses and may require aggressive treatment. Therefore, the early diagnosis and treatment of ductal adenocarcinoma is very important. The ductal adenocarcinoma should be considered in the differential diagnosis of the prostate carcinomas

References

  • Yang XJ, Helpap B, Samaratunga H. Ductaladenocarcinoma. In: Tumours of the urinary system and male genital organs. Eble NJ, Sauter G, Epstein JI, Sesterhenn IA (Editors). IARC Pres Lyon. 2004: 3; 199- 202.
  • Tu WH, Jensen K, Freiha F, Liao JC. A Case of Prostatic Ade- nocarcinoma Recurrence Presenting As Ductal Carcinoma of the Prostate. Nat Clin Pract Urol 2008; 5 (1): 55-58.
  • Eade TN, Al-Saleem T, Horwitz EM, et al. Role of Radiothe- rapy in Ductal (Endometrioid) Carcinoma of the Prostate. Cancer 2007; 109: 2011-2015.
  • Tulunay Ö, Orhan D, Baltacı S, Göğüş Ç, Müftüoğlu YZ. Pros- tatic Ductal Adenocarcinoma Showing Bcl-2 Expression. Int J Urol 2004; 11: 805-808.
  • Vale JA, Patel A, Ball AJ, et al. Endometrioid Carcinoma of the Prostate: A Misnomer? J R Soc Med 1992; 85: 394-396.
  • Guo CC, Epstein JI. Intraductal Carcinoma of the Prostate on Needle Biopsy: Histologic Features and Clinical Significance. Mod Pathol 2006; 19: 1528- 1535.
  • Melicow MM, Pachter MR. Endometrial Carcinoma of Pros- tatic Utricle (uterus masculinus). Cancer 1967; 20: 1715-1722.
  • Epstein JI, Allsbrook WC, Amin MB, Egevad LL. The 2005 In- ternational Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. Am J Surg Pathol 2005; 29: 1228-1242.
  • Christensen WN, Steinberg G, Walsh PC, et al. Prostatic duct adenocarcinoma. Findings at radical prostatectomy. Cancer 1999; 67: 2118–24.
  • Brinker DA, Potter SR, Epstein JI. Ductal adenocarcinoma of the prostate diagnosed on needle biopsy: correlation with cli- nical and radical prostatectomy findings and progression. Am J Sug Pathol 1999; 23: 1471–9
There are 10 citations in total.

Details

Primary Language Turkish
Authors

Burak Özçift This is me

Kaan Bal This is me

Ayşegül Akder Sarı This is me

Yaşar Issı This is me

Ahmet Bölükbaşı This is me

Publication Date January 1, 2012
Published in Issue Year 2012 Volume: 7 Issue: 1

Cite

Vancouver Özçift B, Bal K, Sarı AA, Issı Y, Bölükbaşı A. Hematüri şikayetiyle gelen hastada prostat kanserinin nadir bir varyantı olan prostat duktal adenokarsinomu tanısı. New J Urol. 2012;7(1):66-9.