Böbrek tümörleri içinde renal onkositom sıklığı ve tanıda görüntüleme yöntemlerinin ince iğne aspirasyon biyopsisi indikasyonundaki yeri

Abstract

Amaç: Böbrek tümörü nedeniyle tedavi edilen hastalar içerisinde renal onksitom sıklığını ve tanı için görüntüleme yöntemlerinin mour who underwent surgery and the location ince iğne aspirasyon biyopsisi indikasyonundaof imaging for indication of fine needle aspiratiki yerini araştırdık.Gereç ve Yöntemler: Hastanemizde 2005 ile 2011 yılları arasında böbrek tümörü nedeniyle radikal nefrektomi veya nefron koruyucu cerrahi uygulanan 420 hasta retrospektif olarak incelendi. Renal onkositom saptanan hastalar who diagnosed Renal Oncocytoma RO were radyolojik bulgu ve semptom varlığı, bu hastadetermined in terms of presence of symptoms lara uygulanan tedaviler ve ince iğne aspirasyon biyopsisi ile böbrek biyopsisi uygulanabilirliği applicability of fine needle aspiration biopsy or açısından değerlendirildi.renal biopsy.Bulgular: Renal onkositom sıklığı %2.8 olarak tespit edildi. Bu hastaların 7’sinde %58 radyolojik bulgu izlendi. Hastaların 8’i %67 sed renal oncocytoma had radiological signs. 8 tanı anında semptomatikti. 2 hastaya %17 patients 67% were symptomatic at the time of nefron koruyucu cerrahi, 10 hastaya %83 ise radikal nefrektomi uygulandı.Sonuç: Renal onkositom sıklığı literatür ile uyumlu bulundu. Radyolojik bulgusu olan veya benin-malin ayrımı yapılamayan hastalarda cocytoma was consistent with the literature. We ince iğne aspirasyon biyopsisi veya böbrek bibelieve that performing fine needle aspiration yopsisi yapılmasının gereksiz radikal cerrahileri engelleyeceği kanaatindeyiz

Keywords

• Böbrek tümörleri,ince iğne aspirasyon biyopsisi,renal onkositom

The incidence of renal oncocytoma in renal tumours and the location of imaging for indication of fine needle aspiration biopsy in diagnosis

Abstract

Objective: We’ve investigated the incidence of renal oncocytoma in patients with renal tumour who underwent surgery and the location of imaging for indication of fine needle aspiration biopsy in diagnosis. Material and Methods: 420 patients who underwent radical nephrectomy or nephron sparing surgery between 2005 and 2011 in our hospital were evaluated retrospectively. Patients who diagnosed Renal Oncocytoma RO were determined in terms of presence of symptoms and radiological signs, treatment modalities and applicability of fine needle aspiration biopsy or renal biopsy. Results: The incidence of renal oncocytoma was 2.8% and in 7 patients 58% who diagnosed renal oncocytoma had radiological signs. 8 patients 67% were symptomatic at the time of diagnosis. 2 patients 17% were treated with radical nephrectomy while 10 patients 83% with nephron sparing surgery. Conclusion: The incidence of renal oncocytoma was consistent with the literature. We believe that performing fine needle aspiration biopsy or renal biopsy in patients who have radiological signs or difficulty in differentiation between benign and malignant will prevent unnecessary radical surgeries

Keywords

• Fine needle aspiration biopsy,renal oncocytoma,renal tumour

References

1. Lieber MM, Tomera KM, Farrow GM. Renal oncocytoma. J Urol 1981;125:481–5.
2. Romis L, Cindolo L, Patard JJ, Messina G, Altieri V, Salo- mon L. Frequency, clinical presentation and evolution of renal oncocytomas: multicentric experience from a Euro- pean database. Eur Urol 2004;7:45:53–57.
3. Chow WH, Devesa SS, Warren JL, Fraumeni JF. Rising incidence of renal cell cancer in the United States. JAMA 1999;281:1628-31.
4. Wolf J, Stuart JR. Evaluation and management of solid and cystic renal masses. J Urol 1998;159:1120-33.
5. Novick AC, Campbell SC. Renal Tumors. Philadelphia: Saunders Elsevier 2002. p. 2672-2719.
6. Dechet CB, Zincke H, Sebo TJ, King BF, LeRoy AJ, Far- row GM, et al. Prospective analysis of computerized to- mography and needle biopsy with permanent sectioning to determine the nature of solid renal masses in adults. J Urol 2003;169:71-4.
7. Morra MN, Das S. Renal oncocytoma: a review of histo- genesis, histopathology, diagnosis and treatment. J Urol 1993;150:295-302.
8. Klei MJ, Valensi OJ. Proximal tubular adenomas of kid- ney with socalled oncocytic features. A clinicopathologic study of 13 cases of a rarely reported neoplasm. Cancer 1976;38:906-14.

9. Şahin MO, Canda AE, Mungan MU, Kırkali Z, Sade M. Böbrek tümörü ön tanısıyla radikal nefrektomi yapılan be- nign lezyonlar. Türk Üroloji Dergisi 2004;30:405-9.
10. Quinn MJ, Hartman DS, Friedman AC, Sherman JL, Lau- tin EM, Pyatt RS, et al. Renal oncocytoma: new observati- ons. Radiology 1984;153:49-53.
11. Zhang J, Lefkowitz RA, Bach A. Imaging of kidney cancer. Radiol Clin North Am 2007;45:119-47.
12. Wildberger JE, Adam G, Boeckmann W, Münchau A, Bra- uers A, Günther RW, et al. Computed tomography charac- terization of renal cell tumors in correlation with histopat- hology. Invest Radiol 1997;32:596-601.
13. Khan AA, Shergill IS, Quereshi S, Arya M, Vandal MT, Gujral SS. Percutaneous needle biopsy for indeterminate renal masses: a national survey of UK consultant urolo- gists. BMC Urol 2007;10: 4-7.
14. Lane BR, Samplaski MK, Herts BR, Zhou M, Novick AC, Campbell SC. Renal mass biopsy- a renaissance? J Urol 2008;179:20-7.