Retroperitoneal
sarkomlar tüm yumuşak doku sarkomlarının % 15’ini oluşturan nadir tümörlerdir.
Sıklıkla insidental olarak tanı alan retroperitoneal sarkomlarda en sık
rastlanan histolojik tip liposarkomdur. Retroperitoneal liposarkomlarda yaşam
süresini uzatan majör tedavi şekli geniş cerrahi rezeksiyondur. Cerrahi
sonrası lokal rekürrens ve metastaz riskinden dolayı bu hastaların
multidispliner olarak uzun dönem takip edilmeleri gerekmektedir. Burada ilk
operasyonu sonrası takipsiz kalan ve 16 yıl sonra 24 cm’lik dev
retroperitoneal kitle ile başvuran 72 yaşındaki bir liposarkom olgusuna yaklaşımımızı
sunduk.
4. Lewis JJ, Leung D, Woodruff JM, Brennan MF. Retroperito- neal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg 1998;228:355-65.
5. Goss G, Demetri G. Medical management of unresectable, recurrent low-grade retroperitoneal liposarcoma: integrati- on of cytotoxic and non-cytotoxic therapies into multimo- dality care. Surg Oncol 2000;9:53-9.
6. Hassan I, Park SZ, Donohue JH, et al. Operative manage- ment of primary retroperitoneal sarcomas: a reappraisal of an institutional experience. Ann Surg 2004;239:244-50.
7. Fernández-Ruiz M, Rodríguez-Gil Y, Guerra-Vales JM, et al. Primary retroperitoneal liposarcoma: clinical and histological analysis of ten cases. Gastroenterol Hepatol 2010;33:370-6.
8. Jelinek JS, Kransdorf MJ, Shmookler BM, Aboulafia AJ, Ma- lawer MM. Liposarcoma of the extremities: MR and CT fin- dings in the histologic subtypes. Radiology 1993;186:455-9.
9. Sogaard AS, Laurberg JM, Sorensen M, et al. Intraabdomi- nal and retroperitoneal soft-tissue sarcomas--outcome of surgical treatment in primary and recurrent tumors. World J Surg Oncol 2010;8:81.
10. Henricks WH, Chu YC, Goldblum JR, Weiss SW. Dediffe- rentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dediffe- rentiation. Am J Surg Pathol 1997;21:271-81.
11. Osmanağaoğlu MA, Bozkaya H, Ozeren M, Cobanoğlu U. Primary retroperitoneal liposarcoma. Eur J Obstet Gynecol Reprod Biol 2003;109:228-30.
12. Sharma M, Mannan R, Bhasin TS, Manjari M, Punj R. Giant inflammatory variant of well differentiated liposarcoma: a case report of a rare entity. J Clin Diagn Res 2013;7:1720-1.
13. Le ATJ, Thway K, Huang PH, Jones RL. Clinical and Mole- cular Spectrum of Liposarcoma. J Clin Oncol 2018;36:151- 9.
14. Doglietto GB, Tortorelli AP, Papa V, et al. Giant retroperito- neal sarcomas: a single institution experience. World J Surg 2007;31:1047-54.
15. Bagaria SP, Gabriel E, Mann GN. Multiply recurrent ret- roperitoneal liposarcoma. J Surg Oncol 2017 [Epub ahead ofprint]
16. Fabre-Guillevin E, Coindre JM, Somerhausen Nde S, et al. Retroperitoneal liposarcomas: follow-up analysis of dedif- ferentiation after clinicopathologic reexamination of 86 li- posarcomas and malignant fibrous histiocytomas. Cancer 2006;106:2725-33.
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Recurrence giant retroperitoneal liposarcoma: A case report and review of the literature
Year 2018,
Volume: 13 Issue: 3, 63 - 67, 01.10.2018
Retroperitoneal sarcomas are rare tumors and form 15% of all soft tissue sarcomas. The most common histologic type of
retroperitoneal sarcomas is liposarcoma,
which are frequently diagnosed incidentally.
Major treatment in retroperitoneal liposarcoma is extensive surgical resection. Because of
the risk of local recurrence and metastasis after surgery, these patients should be followed
up by multidiciplinary for a long time. Postoperative follow-up of the patients should be
multidisciplinary.
Herein we presented our approach to a
72-year-old liposarcoma case, who was admitted without follow-up after the first ope-
ration and was presented with a giant retro-
peritoneal mass of 24 cm 16 years later.
4. Lewis JJ, Leung D, Woodruff JM, Brennan MF. Retroperito- neal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg 1998;228:355-65.
5. Goss G, Demetri G. Medical management of unresectable, recurrent low-grade retroperitoneal liposarcoma: integrati- on of cytotoxic and non-cytotoxic therapies into multimo- dality care. Surg Oncol 2000;9:53-9.
6. Hassan I, Park SZ, Donohue JH, et al. Operative manage- ment of primary retroperitoneal sarcomas: a reappraisal of an institutional experience. Ann Surg 2004;239:244-50.
7. Fernández-Ruiz M, Rodríguez-Gil Y, Guerra-Vales JM, et al. Primary retroperitoneal liposarcoma: clinical and histological analysis of ten cases. Gastroenterol Hepatol 2010;33:370-6.
8. Jelinek JS, Kransdorf MJ, Shmookler BM, Aboulafia AJ, Ma- lawer MM. Liposarcoma of the extremities: MR and CT fin- dings in the histologic subtypes. Radiology 1993;186:455-9.
9. Sogaard AS, Laurberg JM, Sorensen M, et al. Intraabdomi- nal and retroperitoneal soft-tissue sarcomas--outcome of surgical treatment in primary and recurrent tumors. World J Surg Oncol 2010;8:81.
10. Henricks WH, Chu YC, Goldblum JR, Weiss SW. Dediffe- rentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dediffe- rentiation. Am J Surg Pathol 1997;21:271-81.
11. Osmanağaoğlu MA, Bozkaya H, Ozeren M, Cobanoğlu U. Primary retroperitoneal liposarcoma. Eur J Obstet Gynecol Reprod Biol 2003;109:228-30.
12. Sharma M, Mannan R, Bhasin TS, Manjari M, Punj R. Giant inflammatory variant of well differentiated liposarcoma: a case report of a rare entity. J Clin Diagn Res 2013;7:1720-1.
13. Le ATJ, Thway K, Huang PH, Jones RL. Clinical and Mole- cular Spectrum of Liposarcoma. J Clin Oncol 2018;36:151- 9.
14. Doglietto GB, Tortorelli AP, Papa V, et al. Giant retroperito- neal sarcomas: a single institution experience. World J Surg 2007;31:1047-54.
15. Bagaria SP, Gabriel E, Mann GN. Multiply recurrent ret- roperitoneal liposarcoma. J Surg Oncol 2017 [Epub ahead ofprint]
16. Fabre-Guillevin E, Coindre JM, Somerhausen Nde S, et al. Retroperitoneal liposarcomas: follow-up analysis of dedif- ferentiation after clinicopathologic reexamination of 86 li- posarcomas and malignant fibrous histiocytomas. Cancer 2006;106:2725-33.
Aydın ME, Bolat D, Kebat T, Aydoğdu Ö, Yonguç T, Bozkurt Hİ, et al. Recurrence giant retroperitoneal liposarcoma: A case report and review of the literature. New J Urol. 2018;13(3):63-7.