Buscke-Löwenstein tümörü dev kondiloma akuminata cerrahi tedavisi: Olgu sunumu

Year 2013, Volume: 8 Issue: 2, 68 - 70, 01.05.2013

Fatih Oğuz Ramazan Altıntaş Ender Akdemir Ali Beytur Cemal Taşdemir Ali Güneş

Abstract

Buschke Löwenstein tümörü olarak ta bilinen dev kondiloma akuminata özellikle genital ve perianal bölgeyi tutan seksüel geçişli nadir bir hastalıktır. Human papilloma virüsünün HPV bu hastalığın gelişimindeki rolü gösterilmiştir. Buschke-Löwenstein tümörü kondüloma akuminatanın farklı varyantıdır. Benign histopatolojisine rağmen sık tekrarlaması ve lokal agresif seyirli olmasıyla karakterizedir. Çok çeşitli tedavi seçeneklerinin kullanılmasına rağmen, yanıt çoğunla düşük ve nüks oranları yüksektir. Bu olgu sunumunda 58 yaşında erkek hastada saptanılan ve cerrahi olarak tedavi edilen dev kondiloma akumunatalı olgu sunuldu

Keywords

Buscke-Löwenstein tümör , kondiloma akuminata , HPV , tedavi.

Buschke Loewenstein tumor giant condyloma acuminatum treatment by surgery alone: A case report

Abstract

Giant condyloma acuminatum, also known as Buschke-Löwenstein tumor BLT is a very rare sexually transmitted disease which primarily affects genital and perianal areas. Human papillomavirus has been identified as contributory to its development. Buschke-Löwenstein tumor is a unique variant of condyloma acuminate. It is categorized by local aggressive behavior and recurrence in spite of benign histology. Although various treatments have been used, response is often poor and recurrence rates high. We present a 58 year old male patient with giant condyloma acuminata which was successfully treated with surgical excision.

Keywords

Buscke-lowenstein tumor , condyloma acuminata , HPV , treatment

References

• Buschke A, Lowenstein L. Über carcinomahnliche condylo- mata acuminata des penis. Klin Wochenschr. 1925;4:1726- 28.
• Buschke A. Condylomata acuminata. In: Neisser A, ed. Ste- reoskopischer Medizinischer Atlas. New York, NY: Fischer; 1896;8: 2.
• Ferizi M, Gercari A, Pajaziti L, et al. Condyloma accumi- nata in child end laser theraphy: a case report. Cases Jour- nal 2009;2: 123.
• Creasman C, Haas PA, Fox TA Jr, Balazs M: Malignant transformation of anorectal giant condyloma acuminatum (Buschke-Löwenstein tumor). Dis Colon Rectum 1989; 32: 481–87.
• Renzi A, Giordano P, Renzi G, et al. Buschke-Lowenstein tumor succesful treatment by surgical excision alone: a case report. Surg Innov 2006; 13: 69-72.
• Chaidemenos G, Kogia M, Souparis A, et al. Radical exci- sion and mesh-skin grafting for giant anorectal condyloma acuminatum. Dermatol Surg 2006; 32: 324-28.
• Geusau A, Heinz-Peer G, Volc-Platzer B, Stingl G, Kirn- bauer R. Regression of deeply inflitrating giant condyloma acuminatum (Buschke- Lowenstein tumor) following long- term intralesional interferon-alfa therapy. Arch Dermatol 2000; 136: 707-10.
• Gillard P, Vanhooteghem O, Richert B, De La Brasine M. Tumor de Buschke-Loewenstein. Ann Dermatol Venereol 2005; 132: 98–99.
• El Mejjad A, Dakır M, Tahırı M, et al. Le condylome acuminé géant-tumeur de Buschke Loewenstein (à propos de 3 cas).Prog Urol 2003; 13: 513–17.
• Ergün SS, Kural YB, Büyükbabani N ve ark. Giant condylo- ma acuminatum. Dermatol Surg 2003; 29: 300-03.
• Ilkay AK, Chodak GW, Vogelsang NJ, Gerber GS. Buschke- Loewenstein tumor: therapeutic options including systemic chemotherapy. Urology.1993;42: 599-601.
• Sobrado CW, Mester M, Nadalin W, et al. Radiation-induced total regression of a highly recurrent giant perianal cond- yloma: report of case. Dis Colon Rectum. 2000;43:257-60.