Skrotal kalsinozis: Etyoloji hala bilinmemekte

Year 2013, Volume: 8 Issue: 3, 74 - 77, 01.08.2013

Osman Köse Şükrü Kumsar Hüseyin Aydemir Elif Alponat Öztuğ Adsan

Abstract

Skrotal kalsinozis, skrotum cildinde multipl, farklı boyutlarda, ağrısız, orta sertlikte nodül gelişimiyle karakterize nadir bir hastalıktır. Skrotal kalsinozisin etyopatogenezi, 1888’de ilk tanımlandığından beri net olarak açıklanamamıştır. Polikliniğimize, skrotumda değişik boyutlarda nodüler cilt lezyonları nedeniyle başvuran 2 hasta, ve rezeke edilen nodüllerin histopatolojik incelemesi, literatür eşliğinde tartışılmıştır. Bulgularımız, epidermal kistlerin, skrotal kalsinozis patogenezinde, önemli bir yolak olduğu hipotezini desteklemektedir. Yine de, ortada kalan önemli bir soru, distrofik kalsifikasyonun neden skrotumu tercih ettiğidir

Keywords

Skrotal kalsinozis , etyoloji

Scrotal calcinosis: The etiology is still unknown

Abstract

Scrotal calcinosis is a rarely encountered disease, characterized by the development of multiple, irregular-sized, non-painful, and moderately hard nodules. Etiopathogenesis of scrotal calcinosis has not been clearly explained since it was first defined in 1888. Two cases presented to our outpatient clinic with that were various sizes and nodular in character, histopathological results of the resected nodules are discussed here with the reference to the literature. Our findings support the hypothesis that epidermal cysts are an important pathway in the pathogenesis of scrotal calcinosis. On the other hand the important question that remains is: Why does dystrophic calcification prefer the scrotum?

Keywords

Scrotal Calcinosis , etiology

References

• Lewinski HM: Lymphangiome der Haut mit ver-kalkten In- halt. Virchows Arch. Pathol. Anat. 1883;91: 371.
• Saad AG, Zaatari GS: Scrotal calcinosis: is it idiopathic? Urology 2001;57:365.
• Dubey S, Sharma R, Maheshwari V. Scrotal calcinosis: Idio- pathic or dystrophic?Dermatol Online J 2010;5:15-16.
• Theuvenet WJ, Nolthenius-Puylaert T, et al. Massive defor- mation of the scrotal wall by idio-pathic calcinosis of the scrotum. Plast Reconstr Surg 1984;74: 539-543.
• Maize J, Metcalf J: Metabolic Disases of the Skin, in Elder D(Ed): Lever’s Histopathology of the Skin. Philadelphia, Lippincott-Raven, 1997, pp 379–382.
• Shapiro L, Platt N, Torres-Rodríguez VM. Idiopathic calci- nosis of the scrotum. Arch Dermatol 1970;102:199-204.
• King DT, Brosman S, Hirose FM, et al: Idiopathic calcinosis of the scrotum. Urology 1979;14: 92-94.
• Pabuççuoğlu U, Canda MS, Güray M et al. The possible role of dartoic muscle degeneration in the pathogenesis of idi- opathic scrotal calcinosis. Br J Dermatol 2003;148: 827-9.
• Wright S, Navsaria H, Leigh MI: Idiopathic scrotal calcino- sis is idiopathic. J Am Acad Derma-tol 1991;24:727-730.
• Song DH, Lee KH, Kang WH. Idiopathic calcinosis of the scrotum: histopathologic observations of fifty-one nodules.J Am Acad Dermatol 1988;19:1095-101.
• Dare AJ, Axelsen RA. Scrotal calcinosis: origin from dystrophic calcification of eccrine duct milia. J Cutan Pat- hol 1988;15:142-9.
• Yahya H, Rafindadi AH. Idiopathic scrotal calcinosis: a re- port of four cases and review of the literature. Int J Derma- tol 2005;44:206-9.