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Overdoz prostat radyasyonunda acil robotik radikal prostatektomi

Year 2015, Volume: 10 Issue: 2, 49 - 51, 01.05.2015

Abstract

67 yaşında prostat adenokarsinom tanılı boost doz yerine, tam doz iodine-125 brakiterapiyi takiben eksternal beam radyoterapi tedavisi alarak tıbbı bir talihsizlik yaşamış hasta, ileri değerlendirme ve radikal prostatektomi için kliniğimize yönlendirildi. Hastaya robotik radikal prostatektomi ve bileteral pelvik lenf nodu diseksiyonu yapıldı. Radyoaktif çekirdekler çıkarıldı ve 10 aylık takipte hastalıksızdı. En önemlisi hastada ciddi pelvik komplikasyonlar yoktu. Aşırı doz radyasyon alan bu tip hastalar radikal prostatektomi için ivedilikle yönlendirmelidir

References

  • Jemal A, Siegel R, Ward E et al. Cancer statistics, 2008. CA Cancer J Clin 2008; 58:71–96.
  • Pinkawa M, Fischedick K, Asadpour B et al. Toxicity profi- le with a large prostate volume after external beam radiot- herapy for localized prostate cancer. Int J Radiat Oncol Biol Phys 2008;70:83–9.
  • Gelblum DY, Potters L, Ashley R et al. Urinary morbidity following ultrasound-guided transperineal prostate seed implantation. Int J Radiat Oncol Biol Phys 1999;45:59–67.
  • Sanderson KM, Penson DF, Cai Jet al. Salvage radical pros- tatectomy: quality of life outcomes and long-term onco- logical control of radio recurrent prostate cancer. J Urol 2006;176: 2025–32.
  • Amling CL, Lerner SE, Martin SK et al. Deoxyribonucle- ic acid ploidy and serum prostate specific antigen predict outcome following salvage prostatectomy for radiation ref- ractory prostate cancer. J Urol 1999;161: 857–63.
  • Ward JF, Sebo TJ, Blute ML, et al. Salvage surgery for radio- recurrent prostate cancer: contemporary outcomes. J Urol 2005;173: 1156–60.
  • Pisters LL, Leibovici D, Blute ML, et al. Locally recurrent prostate cancer after initial radiation therapy: a compari- son of salvage radical prostatectomy versus cryotherapy. J Urol 2009 ;182:517-25.
  • Kaouk JH, Hafron J, Goel R, Haber. Robotic salvage retro- pubic prostatectomy after radiation/brachytherapy: initial results. BJU Int 2008;102:93-6.
  • Eandi JA, Link BA, Nelson RA, Josephson DY et al. Robo- tic assisted laparoscopic salvage prostatectomy for radiati- on resistant prostate cancer. J Urol 2010;183:133-7.

Emergency robotic radical prostatectomy for acute prostate radiation overdose

Year 2015, Volume: 10 Issue: 2, 49 - 51, 01.05.2015

Abstract

A sixty seven-year-old patient who was diagnosed to have prostatic adenocarcinoma, experienced a medical misadventure when he received external beam radiation therapy followed by a full dose of iodine-125 brachytherapy, instead of a boost dose. The patient was referred to our center for further evaluation and possible urgent radical prostatectomy. The patient underwent successful robotic radical retropubic prostatectomy with bilateral lymphnode dissection. Radioactive seeds were removed and the patient remains diseasefree with 10 months follow-up. Most importantly, the patient has not experience any serious pelvic complications. Patients with this type of radiation overdose should be immediately referred for emergency radical prostatectomy

References

  • Jemal A, Siegel R, Ward E et al. Cancer statistics, 2008. CA Cancer J Clin 2008; 58:71–96.
  • Pinkawa M, Fischedick K, Asadpour B et al. Toxicity profi- le with a large prostate volume after external beam radiot- herapy for localized prostate cancer. Int J Radiat Oncol Biol Phys 2008;70:83–9.
  • Gelblum DY, Potters L, Ashley R et al. Urinary morbidity following ultrasound-guided transperineal prostate seed implantation. Int J Radiat Oncol Biol Phys 1999;45:59–67.
  • Sanderson KM, Penson DF, Cai Jet al. Salvage radical pros- tatectomy: quality of life outcomes and long-term onco- logical control of radio recurrent prostate cancer. J Urol 2006;176: 2025–32.
  • Amling CL, Lerner SE, Martin SK et al. Deoxyribonucle- ic acid ploidy and serum prostate specific antigen predict outcome following salvage prostatectomy for radiation ref- ractory prostate cancer. J Urol 1999;161: 857–63.
  • Ward JF, Sebo TJ, Blute ML, et al. Salvage surgery for radio- recurrent prostate cancer: contemporary outcomes. J Urol 2005;173: 1156–60.
  • Pisters LL, Leibovici D, Blute ML, et al. Locally recurrent prostate cancer after initial radiation therapy: a compari- son of salvage radical prostatectomy versus cryotherapy. J Urol 2009 ;182:517-25.
  • Kaouk JH, Hafron J, Goel R, Haber. Robotic salvage retro- pubic prostatectomy after radiation/brachytherapy: initial results. BJU Int 2008;102:93-6.
  • Eandi JA, Link BA, Nelson RA, Josephson DY et al. Robo- tic assisted laparoscopic salvage prostatectomy for radiati- on resistant prostate cancer. J Urol 2010;183:133-7.
There are 9 citations in total.

Details

Primary Language Turkish
Journal Section Original Article
Authors

Mahmoud Mustafa This is me

Louis L Pisters This is me

Publication Date May 1, 2015
Published in Issue Year 2015 Volume: 10 Issue: 2

Cite

Vancouver Mustafa M, Pisters LL. Overdoz prostat radyasyonunda acil robotik radikal prostatektomi. New J Urol. 2015;10(2):49-51.