Bir Kangal köpekte osteosarkom olgusu

Year 2001, Volume: 7 Issue: 1-2, 11 - 13, 01.06.2001

M. Kazım Börkü Arif Kurtdede Ramazan Durgu Selçuk Pekkaya

Abstract

Bu çalışmanın materyalini topallık, iştahsızlık, zayıflama, kalkmakta zorlanma ve ekzersiz intolerans şikayetleri bulunan 9 yaşlı, erkek, bir kangal köpeği oluşturdu. Sahibi son zamanlarda köpeğin kulübesinden çıkmak istemediğinden, yürürken topalladığından şikayet ediyordu. Klinik muayenede zayıflama, özellikle sağ arka bacakta incelme, ekzersizle artan topallık, çevreye karşı ilgisizlik, düşkünlük, depresyon, mukozalarda solgunluk, yürümeye karşı isteksizlik, harekete zorlandığında sağ arka bacağın fleksiyon pozisyonda tutulması, sağ sakral bölgede şişlik ve ağrı, akciğerde patolojik sesler, öksürük ve nabızda düzensizlik saptandı. Radyografık muayenede pelviste sağ ileumun korpusundan ala ossis ileuma kadar uzanan fırçamsı kenar görünümünde düzensiz bir yapı, kalbin, kranial bölge ve bazis’inde düzensiz opasite ve sağ ventriküler dilatasyon gözlendi. Kan serumunda; ALT, ALP, LDH, kalsiyum ve potasyumda artış, albuminde azalma vardı. Eritrosit sayısı ve hemoglobin yoğunluğu normalin alt sınırına inmiş, MCV artmış ve lökosit formülü değişmişti. EKG’de R ve T dalgalarında sivrilme görüldü. Konservatif sağaltım çalışmaları sürdürülürken ölen köpeğin nekropsisinde, pelviste 10x6x3 cm boyutlarında, elastik kıvamda, geniş tabanlı ve dışa doğru taşmış bir kitlenin varlığı belirlendi. Akciğerde yaygın kanama odakları, akciğer arterlerinin lümeninde hiyalinize trombus kitleleri ve neoplastik hücre embolileri, kalp kası hücrelerinde dejeneratif ve nekrotik değişiklikler gözlendi

Keywords

Osteosarkom, Topallık, Köpek

Osteosarcoma in an Anatolian Shepherd Dog

Abstract

A 9-year-old male Anatolian shepherd dog with episodes of lameness, anorexia, weakness, being unable to get up on its pelvic limbs, exercise intolerance, localised pain on pelvic limbs, was used in this case. The ovvners complained the refusal of the dog to get up on his pelvic limbs, to reluctant to go out from his kennel, and to limp when walking. In the clinical examination of the dog, weakness, depression, and pale mucous membranes were the majör fmdings. Hence, the right pelvic limb was less functional and stood with the dorsal aspect of the paw turned över on the ground. Atrophy was also observed in the right gluteal region with the obvious pain perception. Wheezes and crackles on the apical lobes and harsh vesiculo-bronchial sounds in the left lung’s caudal lobes were osculated. Likewise, coughing, irregular pulse rate were examined. Plain radiographs revealed an irregular brush pattern lying from the body of the right ileum to wing of the ileum, an irregular pattem located cranially on the base of the heart, and right ventricular dilatation in the heart. In clinical laboratory studies, a mild erythropoiesis, decrease in haemoglobin concentration, changes in leukocyte percentage count were detected. Serum ALP, ALP, LDH, Ca and potassium were increased. Reversely, serum albumin levels was decreased. At electrocardiography, tali and peaked R wave and T wave were seen. Necropsy was carried out in the dog died during the therapy. A tumoral mass was detected in the pelvis with a size of 10x6x3 cm. It is elastic in nature with a larger base, and protruded through the surface of the pelvic limb. Neoplastic celi embolus and hyaline thrombus4 in the lung, and necrotic and degenerative changes in the heart muscle were also common pathological fmdings

Keywords

Osteosarcoma, Lameness, Dog

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