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Köpeklerde midazolam ve acepromazine’nin ketamin HCL ile kombine anestezisinin kardiopulmoner etkileri ve bu etkilerinin flumezanil ile geri döndürülmesi

Year 2001, Volume: 7 Issue: 1-2, 73 - 80, 01.06.2001

Abstract

Bu çalışma, Y.Y.Ü Veteriner Fakültesi Cerrahi Kliniğinde değişik yaşta 10 adet melez köpek üzerinde gerçekleştirildi. Midazolam, acepromazine, ketamin HCL ve flumezanil uygulamalarından sonra kalp grafısi, klinik semptomlar, vücut ısısı, respirasyon ve pulzasyon düzenli aralıklarla kontrol edildi. Uygulamalarda her hangi bir komplikasyon gözlenmedi. Flumezanil ile anesteziden çıkış süresi her iki grupta ortalama 30 dakika olarak belirlendi

References

  • Reves JG, Fragen RJ, Vinik R : Midazolam:Pharmacology and uses. Anesthesiology 62: 310-324, 1985.
  • Bustamante B, Valverde A, Kaminsky D: Determination of a sedative dose and cardiorespiratory effects of droperidol and midazolam in pigs. Vet. Surg. 22: 85, 86, (1993)
  • Valverde A, Honeyman VL, Dyson DH : Determination of a sedative dose and influence of midazolam on cardiopulmonary function in Canada geese.Am J Vet Res 51: 1071, 1074,(1990).
  • Smith J, Muir WW : Cardiopulmonary effects of midazolam and flumazenil in racing pigeons. Vet surg 21: 499, (1992).
  • Chambers JP, Dopson JM : A midazolam and ketamine combination as a sedative in cats.. J. Assoc. Vet. Anaesth. 16: 53,(1989).
  • Tranguilli WJ. Thurmon JC, Benson GJ : Midazolam premedication decreases thiamylal induction requirement in dogs. In proceedings of the Sixth Annual VMAC Urbana IL (1990).
  • Transguilli WJ, Gross ME, Thurman JC : Evaluation of three midazolam-xylazine mixtures: Preliminary trials in dogs. Vet. Surg. 19:168, (1990).
  • İlki w JE, S üter C, McNeal D : Behavioral effects of midazolam following intravenous and intıamuscular administration in healthy awake cats. İn Proceedings of the Annual Meeting of ACVA Las Vegas, NV, p 17, (1990).
  • Haskins Steve C, Alan M: Opinions in Small Animal Anesthesia. The Veterinary. Clinics of Noıth America., V:22, N: 2. Philadephia March. (1992).
  • Lenexa, Kan. Veterinary pharmaceuticals and biologi cads, 6th ed, Veterinary Medical Publishing Co; 858, (1989).
  • 1. Balleıd S, Sholts T, Kownaski AA: The pharmacokinetics, pharmacological responses and behavior effects of acepromazine in the horse. J Vet Pharmacol Ther 5:21, 31, (1982).
  • Miller PJ, Mailin İCA, Khonke JR,: Responser of horses to acepromazine maleate administeıed orally in a paste. Res Vet Sci, 42:318-325,(1987).
  • Haefely W. : The preclinical pharmacology of flumazenil. Eur J Anaesthesiol (Suppl 2): 25, (1988).
  • Robertson S A, Eberhaı t S : Effıcacy of the intranasal route for administration of Anaesthetic agents to adult rabbits. Lab Anim Sci 44: 159-165,(1994).
  • Smith J, Muir WW: Cardiopulmonary effects of midazolam and flumazenil in racing pigeons. Vet Surg 21: 499, (1992).
  • Rumelin A, Nietgen G, Pirlich M, Thum P, Bischoff S, Schafeıs HJ, Von zur Muhlen A, Kiıchner : Postoperative pattern of various hormonal and metabolic variables. A pilot study in patients without complications following cardiac surgery. Curr Med Res 15 (4):339,48, (1999).
  • Sourgiadaki A, Konstantopoulos K, Raggou D, Mpairaktari E, Moretis K: A comparative study of conventional inhalation anesthesia and total intravenous anesthesia (TNA) performed with midazolam and alfentanil. Minerva Anestesiol The Veterinary Clinics of North America Small Animal Practice. 60 (12): 715, 718, (1994).
  • Yılmaz, B.: Fizyoloji, Feryal Matbaacılık, 2.Baskı. Ankara, (2000).
  • Başoğlu A. Veteriner Kardiyoloji. S.Ü. Veteriner Fakültesi, Konya, (1992).

Cardiopulmonar effects of midazolam and acetpromazine and ketamin HCL anesthesia in dogs, and recovering after flumezanil injection

Year 2001, Volume: 7 Issue: 1-2, 73 - 80, 01.06.2001

Abstract

This study was performed in ten cross- bred dogs which were at different ages at the University of Yuzuncu Yil, Faculty of Veterinary Medicine, Department of Surgery. Clinical symptoms, rectal temperature, respiration, pulsation and ECG were taken at regular interwals after midazolam, acepromazine, ketamin HCL and flumezanil application to the dogs. Otherwise complications did not develop after applications of these drugs. Recovering from the anesthesia after flumezanil injection took about 30 minutes in both groups

References

  • Reves JG, Fragen RJ, Vinik R : Midazolam:Pharmacology and uses. Anesthesiology 62: 310-324, 1985.
  • Bustamante B, Valverde A, Kaminsky D: Determination of a sedative dose and cardiorespiratory effects of droperidol and midazolam in pigs. Vet. Surg. 22: 85, 86, (1993)
  • Valverde A, Honeyman VL, Dyson DH : Determination of a sedative dose and influence of midazolam on cardiopulmonary function in Canada geese.Am J Vet Res 51: 1071, 1074,(1990).
  • Smith J, Muir WW : Cardiopulmonary effects of midazolam and flumazenil in racing pigeons. Vet surg 21: 499, (1992).
  • Chambers JP, Dopson JM : A midazolam and ketamine combination as a sedative in cats.. J. Assoc. Vet. Anaesth. 16: 53,(1989).
  • Tranguilli WJ. Thurmon JC, Benson GJ : Midazolam premedication decreases thiamylal induction requirement in dogs. In proceedings of the Sixth Annual VMAC Urbana IL (1990).
  • Transguilli WJ, Gross ME, Thurman JC : Evaluation of three midazolam-xylazine mixtures: Preliminary trials in dogs. Vet. Surg. 19:168, (1990).
  • İlki w JE, S üter C, McNeal D : Behavioral effects of midazolam following intravenous and intıamuscular administration in healthy awake cats. İn Proceedings of the Annual Meeting of ACVA Las Vegas, NV, p 17, (1990).
  • Haskins Steve C, Alan M: Opinions in Small Animal Anesthesia. The Veterinary. Clinics of Noıth America., V:22, N: 2. Philadephia March. (1992).
  • Lenexa, Kan. Veterinary pharmaceuticals and biologi cads, 6th ed, Veterinary Medical Publishing Co; 858, (1989).
  • 1. Balleıd S, Sholts T, Kownaski AA: The pharmacokinetics, pharmacological responses and behavior effects of acepromazine in the horse. J Vet Pharmacol Ther 5:21, 31, (1982).
  • Miller PJ, Mailin İCA, Khonke JR,: Responser of horses to acepromazine maleate administeıed orally in a paste. Res Vet Sci, 42:318-325,(1987).
  • Haefely W. : The preclinical pharmacology of flumazenil. Eur J Anaesthesiol (Suppl 2): 25, (1988).
  • Robertson S A, Eberhaı t S : Effıcacy of the intranasal route for administration of Anaesthetic agents to adult rabbits. Lab Anim Sci 44: 159-165,(1994).
  • Smith J, Muir WW: Cardiopulmonary effects of midazolam and flumazenil in racing pigeons. Vet Surg 21: 499, (1992).
  • Rumelin A, Nietgen G, Pirlich M, Thum P, Bischoff S, Schafeıs HJ, Von zur Muhlen A, Kiıchner : Postoperative pattern of various hormonal and metabolic variables. A pilot study in patients without complications following cardiac surgery. Curr Med Res 15 (4):339,48, (1999).
  • Sourgiadaki A, Konstantopoulos K, Raggou D, Mpairaktari E, Moretis K: A comparative study of conventional inhalation anesthesia and total intravenous anesthesia (TNA) performed with midazolam and alfentanil. Minerva Anestesiol The Veterinary Clinics of North America Small Animal Practice. 60 (12): 715, 718, (1994).
  • Yılmaz, B.: Fizyoloji, Feryal Matbaacılık, 2.Baskı. Ankara, (2000).
  • Başoğlu A. Veteriner Kardiyoloji. S.Ü. Veteriner Fakültesi, Konya, (1992).
There are 19 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

İsmail Alkan This is me

Zafer Okumuş This is me

Burhanettin Baydaş This is me

Loğman Aslan This is me

Musa Gençcelep This is me

Bahtiyar Bakı This is me

Tuncer Çakmak This is me

Publication Date June 1, 2001
Published in Issue Year 2001 Volume: 7 Issue: 1-2

Cite

APA Alkan, İ., Okumuş, Z., Baydaş, B., Aslan, L., et al. (2001). Köpeklerde midazolam ve acepromazine’nin ketamin HCL ile kombine anestezisinin kardiopulmoner etkileri ve bu etkilerinin flumezanil ile geri döndürülmesi. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 7(1-2), 73-80.
AMA Alkan İ, Okumuş Z, Baydaş B, Aslan L, Gençcelep M, Bakı B, Çakmak T. Köpeklerde midazolam ve acepromazine’nin ketamin HCL ile kombine anestezisinin kardiopulmoner etkileri ve bu etkilerinin flumezanil ile geri döndürülmesi. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. June 2001;7(1-2):73-80.
Chicago Alkan, İsmail, Zafer Okumuş, Burhanettin Baydaş, Loğman Aslan, Musa Gençcelep, Bahtiyar Bakı, and Tuncer Çakmak. “Köpeklerde Midazolam Ve acepromazine’nin Ketamin HCL Ile Kombine Anestezisinin Kardiopulmoner Etkileri Ve Bu Etkilerinin Flumezanil Ile Geri döndürülmesi”. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 7, no. 1-2 (June 2001): 73-80.
EndNote Alkan İ, Okumuş Z, Baydaş B, Aslan L, Gençcelep M, Bakı B, Çakmak T (June 1, 2001) Köpeklerde midazolam ve acepromazine’nin ketamin HCL ile kombine anestezisinin kardiopulmoner etkileri ve bu etkilerinin flumezanil ile geri döndürülmesi. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 7 1-2 73–80.
IEEE İ. Alkan, Z. Okumuş, B. Baydaş, L. Aslan, M. Gençcelep, B. Bakı, and T. Çakmak, “Köpeklerde midazolam ve acepromazine’nin ketamin HCL ile kombine anestezisinin kardiopulmoner etkileri ve bu etkilerinin flumezanil ile geri döndürülmesi”, Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, vol. 7, no. 1-2, pp. 73–80, 2001.
ISNAD Alkan, İsmail et al. “Köpeklerde Midazolam Ve acepromazine’nin Ketamin HCL Ile Kombine Anestezisinin Kardiopulmoner Etkileri Ve Bu Etkilerinin Flumezanil Ile Geri döndürülmesi”. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 7/1-2 (June 2001), 73-80.
JAMA Alkan İ, Okumuş Z, Baydaş B, Aslan L, Gençcelep M, Bakı B, Çakmak T. Köpeklerde midazolam ve acepromazine’nin ketamin HCL ile kombine anestezisinin kardiopulmoner etkileri ve bu etkilerinin flumezanil ile geri döndürülmesi. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2001;7:73–80.
MLA Alkan, İsmail et al. “Köpeklerde Midazolam Ve acepromazine’nin Ketamin HCL Ile Kombine Anestezisinin Kardiopulmoner Etkileri Ve Bu Etkilerinin Flumezanil Ile Geri döndürülmesi”. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, vol. 7, no. 1-2, 2001, pp. 73-80.
Vancouver Alkan İ, Okumuş Z, Baydaş B, Aslan L, Gençcelep M, Bakı B, Çakmak T. Köpeklerde midazolam ve acepromazine’nin ketamin HCL ile kombine anestezisinin kardiopulmoner etkileri ve bu etkilerinin flumezanil ile geri döndürülmesi. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2001;7(1-2):73-80.