Year 2009,
Volume: 20 Issue: 1, 49 - 51, 01.03.2009
Abstract
Keywords
References
- Christie WW (1992). Gas Chromatography and Lipids, The Oil Press, Glasgow, p 302.
- Gibbons GF (2003). Regulation of fatty acid and cholesterol synthesis, co-operation or competition? Progress in Lipid Research, 42, 479–497.
- Hall LW, Clarke KW, Trim CM (2001). Veterinary Anaesthesia. Sounders, London, pp 1-145.
- Joubert KE, Lobetti R (2002). The cardiovascular and respiratory effects of medetomidine and thiopentone anaesthesia in dogs breathing at an altitude of 1486 m. J South Afr Vet Assoc, 73(3),104-110.
- Kabara S, Hirota K, Yoshioka H, Kudo T, Ishihara H, Matsuki A (2003). Differential effects of thiopental on methacholine- and serotonin-induced bronchoconstriction in dogs. Br J Anaesth, 91(3),379-384.
- Ko JC, Mandsager RE, Lange DN, Fox SM (2000). Cardiorespiratory concentrations in dogs treated with medetomidine before undergoing ovariohysterectomy. J Am Vet Med Assoc, 217(4),509-514. and plasma cortisol
- Kojima K, Nishimura R, Mutoh T, Hong SH, Mochizuki M, Sasaki N (2002). Effects of medetomidine-midazolam, acepromazine-butorphanol, and midazolam-butorphanol on induction dose of thiopental and propofol and on cardiopulmonary changes in dogs. Am J Vet Res, 63(12),1671- 1679.
- Lobetti R, Lambrechts N (2000). Effects of general anesthesia and surgery on renal function in healthy dogs. Am J Vet Res, 61(2),121-124.
- Lumb WV, Jones EW (1984). Veterinary Anesthesia. Lea and Febiger, Philadelphia, pp 187-304.
- Luna SP, Cassu RN, Castro GB, Teixeira-Neto FJ, Silva-Junior JR, Lopes MD (2004). Effects of four anaesthetic protocols on the neurological and cardiorespiratory variables of puppies born by caesarean section. Vet Rec, 154(13), 387-389.
- Maldonado EN, Romero JR, Ochoa B, Aveldano MI (2001). Lipid and fatty acid composition of canine lipoproteins. Comparative Biochemistry and Physiology - Part B, Biochemistry & Molecular Biology, 128(4),719-29.
- Murray RK, Granner DK, Mayes PA, Rodwell VW (2000). Harper’s Biochemistry, New York, p 160.
- Nakamura MT, Nara TY (2004). Structure, function, and dietary regulation of delta 6, delta 5, and delta 9 desaturases. Ann Rev Nutr, 24,345-76.
- Redondo JI, Gomez-Villamandos RJ, Dominguez JM, Santisteban JM (2000). Propofol or thiopentone as induction agents anesthetized dogs, a preliminary study. J Vet Res, 64(4), 249- 253. and halothane-N2O
- Saevik BK, Thoresen SI, Taugbol O (2002). Fatty acid composition of serum lipids in atopic nd healthy dogs. Res Vet Sci, 73, 153-158.
- Taugbol O, Baddaky-Taugbol B, Saarem K (1998). The fatty acid profile of subcutaneous fat and blood plasma in pruritic dogs and dogs without skin problems. Can J Vet Res, 62, 275- 278.
- Vecka M, Tvrzicka E, Stankova B, Zak A (2002). Effect of column and software on gas chromatographic determination of fatty acids. J Chromatogr B, Analytical Technologies in the Biomedical and Life Sciences, 25, 770(1-2),91-99.
Year 2009,
Volume: 20 Issue: 1, 49 - 51, 01.03.2009
Abstract
Bu çalışmada 5 kontrol grubu (KG) ve 5 ksilazin-tiopental grubu (KTG) köpekte yağ asitlerinin tip ve konsantrasyon profili araştırıldı. KG’u köpeklerin kan örnekleri alındıktan sonra tiopental ile ötenazi edilip böbrek ve karaciğerlerinden doku örnekleri alındı. KTG’u olgular i.m. 1.5 mg/kg ksilazin hidroklorid ve i.v 20 mg/kg tiopental sodyum verilerek aneztezi edildiler. KTG’u olgular anesteziden tamamen çıkıp kan örnekleri alındıktan sonra tiopental verilerek ötenazi edilip karaciğer ve böbreklerinden doku parçası alındı. Alınan tüm örnekler gaz kromotografisi kullanılarak analiz edildiler. Analiz sırasında KG’unun serum, karaciğer ve böbreklerinden sırasıyla 12, 17 ve 18, KTG’unun serum, karaciğer ve böbreklerden 13, 19 ve 17 farklı tipte yağ asidi saptandı. KTG’unun verileri KG’nununki ile karşılaştırıldığında böbreklerdeki palmitik asit (C16:0) ve stearik asit (C18:0) ile karaciğerdeki linoleik asit (C18:2n-6) verilerinde azalma, buna karşın karaciğerdeki eikosatrienoik asit (C20:3n-9) miktarında belirgin bir artış saptandı. Ayrıca KTG’unun serum, karaciğer ve böbreklerindeki toplam yağ asidi konsantrasyonunun KG’undakilerden yüksek olduğu fakat bu yüksekliğin istatsitiksel olarak önemli olmadığı gözlemlendi. Sonuç olarak, mevcut verilerden ksilazintiopentalın yağ aistleri profili üzerine hücresel düzeyde etki oluşturabileceği kanısına varıldı
Keywords
References
- Christie WW (1992). Gas Chromatography and Lipids, The Oil Press, Glasgow, p 302.
- Gibbons GF (2003). Regulation of fatty acid and cholesterol synthesis, co-operation or competition? Progress in Lipid Research, 42, 479–497.
- Hall LW, Clarke KW, Trim CM (2001). Veterinary Anaesthesia. Sounders, London, pp 1-145.
- Joubert KE, Lobetti R (2002). The cardiovascular and respiratory effects of medetomidine and thiopentone anaesthesia in dogs breathing at an altitude of 1486 m. J South Afr Vet Assoc, 73(3),104-110.
- Kabara S, Hirota K, Yoshioka H, Kudo T, Ishihara H, Matsuki A (2003). Differential effects of thiopental on methacholine- and serotonin-induced bronchoconstriction in dogs. Br J Anaesth, 91(3),379-384.
- Ko JC, Mandsager RE, Lange DN, Fox SM (2000). Cardiorespiratory concentrations in dogs treated with medetomidine before undergoing ovariohysterectomy. J Am Vet Med Assoc, 217(4),509-514. and plasma cortisol
- Kojima K, Nishimura R, Mutoh T, Hong SH, Mochizuki M, Sasaki N (2002). Effects of medetomidine-midazolam, acepromazine-butorphanol, and midazolam-butorphanol on induction dose of thiopental and propofol and on cardiopulmonary changes in dogs. Am J Vet Res, 63(12),1671- 1679.
- Lobetti R, Lambrechts N (2000). Effects of general anesthesia and surgery on renal function in healthy dogs. Am J Vet Res, 61(2),121-124.
- Lumb WV, Jones EW (1984). Veterinary Anesthesia. Lea and Febiger, Philadelphia, pp 187-304.
- Luna SP, Cassu RN, Castro GB, Teixeira-Neto FJ, Silva-Junior JR, Lopes MD (2004). Effects of four anaesthetic protocols on the neurological and cardiorespiratory variables of puppies born by caesarean section. Vet Rec, 154(13), 387-389.
- Maldonado EN, Romero JR, Ochoa B, Aveldano MI (2001). Lipid and fatty acid composition of canine lipoproteins. Comparative Biochemistry and Physiology - Part B, Biochemistry & Molecular Biology, 128(4),719-29.
- Murray RK, Granner DK, Mayes PA, Rodwell VW (2000). Harper’s Biochemistry, New York, p 160.
- Nakamura MT, Nara TY (2004). Structure, function, and dietary regulation of delta 6, delta 5, and delta 9 desaturases. Ann Rev Nutr, 24,345-76.
- Redondo JI, Gomez-Villamandos RJ, Dominguez JM, Santisteban JM (2000). Propofol or thiopentone as induction agents anesthetized dogs, a preliminary study. J Vet Res, 64(4), 249- 253. and halothane-N2O
- Saevik BK, Thoresen SI, Taugbol O (2002). Fatty acid composition of serum lipids in atopic nd healthy dogs. Res Vet Sci, 73, 153-158.
- Taugbol O, Baddaky-Taugbol B, Saarem K (1998). The fatty acid profile of subcutaneous fat and blood plasma in pruritic dogs and dogs without skin problems. Can J Vet Res, 62, 275- 278.
- Vecka M, Tvrzicka E, Stankova B, Zak A (2002). Effect of column and software on gas chromatographic determination of fatty acids. J Chromatogr B, Analytical Technologies in the Biomedical and Life Sciences, 25, 770(1-2),91-99.
There are 17 citations in total.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | March 1, 2009 |
| Published in Issue | Year 2009 Volume: 20 Issue: 1 |