Mast Hücre Heterojenitesi

Year 2005, Volume: 16 Issue: 2, 57 - 60, 01.06.2005

Turan Karaca Mecit Yörük

Abstract

Keywords

-

Mast Hücre Heterojenitesi

Abstract

Mast hücreleri organizmanın histamin ve heparin depo hücreleridir. Bağdokunun bu iri hücreleri granülleri içerisinde histamin ve heparin ile birlikte hayvan türlerine göre değişik oran ve miktarda serotonin, eozinofilik kemotaktik faktör, N - asetil – B – glukosaminidaz, B – glukoronidaz, triptaz, kimaz, prostaglandin D2, RMCP I ve RMCP II gibi maddeleri de taşımaktadırlar. Bu hücreler, rutin histolojik kesitlerin hematoksilen–eozin boyamasında görülemezler. Bu derlemede, mast hücrelerinin granül içeriği, boyanma özellikleri ve tespitlere karşı verdiği reaksiyonları gibi farklı kriterlerle ortaya çıkan heterojenitesinin açıklanması amaçlanmıştır

Keywords

Mast hücresi, heterojenite

References

• Atkins FM, Friedmen MM, Subra Rao PV, Metcalfe DD (1985): Interaction between mast cells, fibroblast and connective tissue components, Int. Arch. Allergy appl. Imm., 77, 96-102.
• Banks WJ (1986): Appleid Veterinary Histology, Second Edition, Williams and Wilkins Co. Baltimore.
• Befus AD, Bienenstock J, Denburg JA (1986): eds. Mast cell differentiation and heterogeneity. New York: Raven Pres.
• Befus D, Goodarce R, Dyck N, Bienenstock J (1985): Mast cell heterogeneity in man. I. Histologic studies of the intestine, Int. Arch. Allergy appl. Imm., 76, 232-236.
• Canpolat L (1997): Mast hücreleri, Fırat Tıp Dergisi, 1(4), 267-274.
• Chen W, Alley MR, Manktelow BW, Davey P (1990): Mast cells in the ovine respiratory tract: Heterogeneity, morphology and density, Int. Arch. Allergy appl. Imm., 93, 99-106.
• Chui H, Lagunoff D (1972): Histochemical comparison of vertabrate mast cells, Histochem. J., 4, 135-144.
• Crowle PK, Reed ND (1984): Bone marrow origin of mucosal mast cells. Int. Arch. Allergy appl. Immunol., 73, 242-247.
• Dvorak AM, McLeod RS, Onderdonk AB, Monahan-Earley RA, Cullen JB, Antolioni DA, Morgan E, Blair JE, Estrella P, Cisneros RL, Cohen Z, Silen W (1992): Human gut mucosal mast cells: Ultrastructural observations and anatomic variation in mast cell-nerve associations in vivo. Int. Arch. Allergy Immunol., 98, 158-168.
• Enerback L (1966): Mast cells in rat gastrointestinal mucosa: I. Effects of fixation, Acta Path. et Microbiol. Scandinav., 66, 289-302.
• Enerback L (1966): Mast cells in rat gastrointestinal mucosa. II. Dye-binding and metachromatic properties, Acta Pathol. et Microbiol. Scandinav. 66, 303-312.
• Enerback L (1981): The gut mucosal mast cell, Monogr. Allergy, 17, 222-232.
• Fox CC, Dvorak AM, Peters SP, Kagey- Sobotka A, Lichtenstein LM (1985): Islotation and characterization of human intestinal mucosal mast cells, J. Immunol., 135, 483-487.
• Galli SJ (1990): New insights into “the riddle of mast cells” microenvironmental regulationof mast cell development and phenotypic heterogeneity, Lab. Invest., 62, 5-33.
• Hakanson R, Böttcher G, Ekblad E, Panula P, Simonsson M, Dohlsten M (1986): Histamine in endocrine in cells in the stomach, Histochemistry, 86, 5- 17.
• Hunt C, Campell AM, Robinson C, Holgate T (1991): Structural and secretory characteristics of bovine lung and skin mast cells: evidence for the existence of heterogeneity, Clin. Exp. Allergy, 21, 173- 182.
• Huntley JF (1992): Mast cells and basophils: A review of their heterogeneity and function, J. Comp. Path., 107, 349-372.
• Irani AA, Schwartz LB (1989): Mast cell heterogeneity (Review), Clin. Exp. Allergy, 19, 143-155.
• Irani AA, Schechter NM, Craig SS, DeBlois G, Schwartz LB (1986): Two human mast cell subsets with distinct neutral protease compositions, Proc. Natl. Acad. Sci. USA, 83(12), 4464-4468.
• Junqueira LC, Carneiro J, Kelley RO (1992): Basic Histology; 4th Ed. Lange Medical Publications, California.
• Kanakura Y, Thompson H, Nakano T, Yamamura T, Asai H, Kitamura Y, Metcalfe DD, Galli SJ (1988): Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells, Blood, 72, 877-882.
• Kitamura Y, Kanakura Y, Sonoda S, Asai H, Nakano T (1987): Mutual phenotypic changes between connective tissue type and mucosal mast cell, Int. Arch Allergy applied Imm., 82, 244-248.
• Lee TD, Swieter M, Bienenstock J, Befus AD (1985): Heterogeneity in mast cell populations. Clin. Immunol. Rev., 4(2), 143 - 199.
• Leeson TS, Leeson CR, Paparo AA (1988): Text / Atlas of Histology, WB Saunders CO, Philadelphia.
• Pearce FL (1986): On the heterogeneity of mast cells (Current Review), Pharmaocology, 32, 61-71.
• Ribatti D, Contino R, Quondamatteo F, Formica V, Tursi A (1992): Mast cell populations in the chick embryo lung and their response compound 48/80 and dexamethasone, Anatomy and Embryology, 186, 241- 244.
• Saavedra-Delgado AMP, Turpin S, Metcalfe DD (1984): Typical and atypical mast cells of the rat gastrointestinal system: distribution and correlation with tissue histamine, Agents and Actions, 14(1), 1-7.
• Sağlam M, Aştı RN, Özer A (1997): Genel Histoloji, Genişletilmiş 5. Baskı, Yorum Basın Yayın Sanayi Ldt. Şti., Ankara.
• Schwartz LB (1989): Heterogeneity of mast cells in humans, in “Mast cell and basophil differentiation and function in health and disease” Editors, SJ Galli, KF Austen, Raven Press, New York.
• Schwartz LB, Austen KF (1984): Structure and function of the chemical mediators of mast cells, Prog. Allergy (Karger Basel), 34, 271-321.
• Shanahan F (1994): The Intestinal Immune System, in “Physiology of the Gastrointestinal Tract”, Editor-in-Chief: LR Johnson, 3th Ed., Vol. 1, 643-684, Raven Press, New York.
• Shanahan F, Denburg JA, Fox J, Bienenstock J, Befus D (1985): Mast cell heterogeneity: Effects of neuroenteric peptides on histamine release, J. Immunol., 135(2), 1331-1337.
• Sredni B, Freidmen M, Bland C, Metcalfe D (1983): Ultrastructural biochemical and functional characteristics of histamine containing cells cloned from mouse bone marrow: tentative identification as mucosal mast cells, J. Immunol., 131, 915-920.
• Stevens RL, Lee TD, Seldin DC, Austen KF, Befus AD, Bienenstock J. (1986): Intestinal mucosal mast cells from rats infected with Nippostrongylus Brasiliensis contain protease-resistant chondroitin sulfate di-B proteoglycans, J. Immunol., 137(1), 291-295.
• Wang T (1991): Mast cells in chicken digestive tract. I. Development, Tokai J. Exp. Clin. Med., 16(1), 21-26.
• Wang T (1991): Mast cells in chicken digestive tract. II.Fixation, distibution, histochemistry and ultrastructure, Tokai J. Exp. Clin. Med., 16(1), 27-32.
• Wingren U, Enerback L (1983): Mucosal mast cells of the rat intestine: a re-evaluation of fixation and staining properties, with special reference to protein blocking and solubility of the granular glycosaminoglycan, Histochem. J., 15, 571-582.
• Yörük M (1994): Koyun ve Keçi Derisinde Mast Hücreleri Üzerinde Morfolojik ve Histometrik Araştırmalar, Doktora Tezi, A.Ü. Sağlık Bilimleri Enstitüsü Ankara.