Objectives. Preoperative imaging studies are commonly used in the
diagnosis of primary hyperparathyroidism to increase the success rate of
surgery. In the present study, we aimed to correlate surgical outcomes with the
sensitivity of localization studies that were performed by various radiologists. Methods. One
hundred eighty-nine patients with preoperative diagnosis primary hyperparathyroidism
were included. A total of 174 patients in whom hypercalcemia had been cured by
parathyroidectomy, were evaluated retrospectively. In total, 184 lesions were
excised from these 174 patients. Ultrasonography (USG) and technetium-99m-methoxy isobutyl isonitrile (99mTc-MIBI) imaging
yielded correctly localized lesion in 74 and 108 patients, respectively. Results.
The specificity of USG and 99mTc-MIBI imaging were similar (95.9%
and 95.0%, respectively). However, the sensitivity was not satisfactory (45.9%
for USG, 62.4% for 99mTc-MIBI). The gland size was not significant
for the rate of lesion detection by 99mTc-MIBI scan or USG.
Significant differences were not observed between the preoperative serum
parathormone, serum calcium or 24-hour urine calcium excretion levels and the
success rate of localization with either USG or 99mTc-MIBI. Conclusions.
Radiologist experience in ultrasonographic parathyroid imaging was found to
affect sensitivity. Therefore, surgeons, radiologists and endocrinologists that
perform ultrasonographic evaluation should have extensive experience.
primary hyperparathyroidism parathyroidectomy localization studies ultrasonography technetium-99m-methoxy isobutyl isonitrile
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Original Article |
Yazarlar | |
Yayımlanma Tarihi | 4 Nisan 2018 |
Gönderilme Tarihi | 10 Mayıs 2017 |
Kabul Tarihi | 14 Ekim 2017 |
Yayımlandığı Sayı | Yıl 2018 Cilt: 4 Sayı: 2 |