Year 2019, Volume 5, Issue 1, Pages 94 - 97 2019-01-04

Neurological findings in autosomal dominant polycystic kidney disease

Demet Yıldız [1] , Abdülmecit Yıldız [2]

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Objective: Autosomal dominant polycystic kidney disease (ADPKD) mainly affects the kidneys, but other abnormalities like intracranial aneurysms (ICAs) are not uncommon. In this study, we aimed to investigate retrospectively frequency of ICA and other neurological abnormalities in ADPKD patients.

Methods: One hundred and forty patients with ADPKD who did not receive replacement therapy and followed-up at outpatient clinic were evaluated.

Results: The mean age of the patients was 43.4 ± 13 years and mean glomerular filtration rate was 87 ± 15 ml/min. ICA was detected in four (2.8%) patients. Three patients were from the same family. Thirteen (9.3%) patients had magnetic resonance angiography due to their family stories, but aneurysm was not seen in them.

Conclusion: Individuals with ADPKD who have a history of aneurysm or hemorrhage in their family should be screened for aneurysm due to mortality and risk of recurrent rupture. 

Autosomal dominant, polycystic kidney disease, intracranial aneurysms, arachnoid cysts
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Primary Language en
Subjects Health Care Sciences and Services
Journal Section Original Articles

Orcid: 0000-0003-0807-8980
Author: Demet Yıldız (Primary Author)
Institution: Department of Neurology, University of Health Sciences, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey
Country: Turkey

Orcid: 0000-0001-5941-9103
Author: Abdülmecit Yıldız
Institution: Department of Neurology, Uludağ University School of Medicine, Bursa, Turkey
Country: Turkey


Publication Date: January 4, 2019

EndNote %0 The European Research Journal Neurological findings in autosomal dominant polycystic kidney disease %A Demet Yıldız , Abdülmecit Yıldız %T Neurological findings in autosomal dominant polycystic kidney disease %D 2019 %J The European Research Journal %P -2149-3189 %V 5 %N 1 %R doi: 10.18621/eurj.379970 %U 10.18621/eurj.379970