Year 2019, Volume 5, Issue 2, Pages 355 - 360 2019-03-04

The association between lipid profile and bone mineral density in subjects with ankylosing spondylitis

Betül Sargın [1] , Gülcan Gürer [2] , Hakan Öztürk [3]

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Objective: This study aims to investigate the relationship between serum lipids and bone mineral density in ankylosing spondylitis patients.

Methods: A total of 94 ankylosing spondylitis patients fulfilling the 1984 Modified New York Criteria who had serum lipid levels and bone mineral density scores in medical records were included in this study. These patients treated with nonsteroid antiinflammatory drugs. Their files were examined in detail. Later demographic and laboratory features were recorded to the research form. Dual-energy X-ray absorptiometry was used to assess bone mineral density in two bone sites of femur (neck, intertrochanteric zone and trochanter) and spinal lumbar vertebras (Lumbar 1-Lumbar 4).

Results: Significant and positive correlation was found between high density lipoprotein and femoral neck bone mineral density (r = 0.356, p = 0.021) in osteopenic group and in osteoporotic group (r = 0.005, p = 0.040).

Conclusion: According to our study significant and positive correlations are found between high density lipoprotein and femoral neck bone mineral density in osteopenic and osteoporotic group. However, we believe that more studies are needed about this research. 

Ankylosing spondylitis, lipid profile, bone mineral density
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Primary Language en
Subjects Health Care Sciences and Services
Journal Section Original Articles
Authors

Orcid: 0000-0002-9463-8413
Author: Betül Sargın (Primary Author)
Institution: Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Adnan Menderes University School of Medicine, Aydın, Turkey
Country: Turkey


Orcid: 0000-0002-4012-6180
Author: Gülcan Gürer
Institution: Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Adnan Menderes University School of Medicine, Aydın, Turkey
Country: Turkey


Orcid: 0000-0001-8112-4934
Author: Hakan Öztürk
Institution: Department of Biostatistics, Adnan Menderes University School of Medicine, Aydın, Turkey
Country: Turkey


Dates

Publication Date: March 4, 2019

EndNote %0 The European Research Journal The association between lipid profile and bone mineral density in subjects with ankylosing spondylitis %A Betül Sargın , Gülcan Gürer , Hakan Öztürk %T The association between lipid profile and bone mineral density in subjects with ankylosing spondylitis %D 2019 %J The European Research Journal %P -2149-3189 %V 5 %N 2 %R doi: 10.18621/eurj.359518 %U 10.18621/eurj.359518