Year 2019, Volume 5, Issue 3, Pages 490 - 496 2019-05-04

Increased TIMI frame count of coronary arteries in patients with myocardial bridging

Ekrem Aksu [1] , Hakan Güneş [2]

107 299

Objectives: Myocardial bridging (MB) is associated with recurrent chest pain and cardiovascular events. Recently it has been proposed that MB has the features of vasospastic coronary artery characterized with reduced coronary flow reserve and endothelial dysfunction. In this study, an evaluation was made of the angiographic Thrombolysis in Myocardial Infarction (TIMI) frame counts (TFCs) of patients with normal angiogram and those with MB.

Methods: The study was conducted as a retrospective analysis of the demographic, laboratory, and angiographic features of consecutive patients who underwent coronary angiography between January 2014 and December 2017 in Necip Fazıl City Hospital and Sütçü Imam University, Kahramanmaraş, Turkey.

Results: The except for age (51.1 ± 11.6 years vs 56.8 ± 11.4 years) (p = 0.011), no difference was determined between the groups in respect of laboratory parameters and demographic features. TFCs of LAD (42.9 ± 6.1 vs 54.5 ± 11.5. p < 0.001), Cx (19.4 ± 4.5 vs 24.4 ± 7.1, p < 0.001), and RCA (26.8 ± 6.2 vs 32.5 ± 8.9, p < 0.001), and corrected TFC of LAD artery (25.2 ± 3.6 vs 32.0 ± 6.8, p < 0.001) were observed to be significantly increased in patients with MB compared to patients with normal coronary flow. Multiple regression analysis revealed that MB was the only determinant of increased corrected TFC of LAD artery (r=0.537, Adjusted r=0.281, p < 0.001).

Conclusions: Patients with MB had abnormally slow coronary flow demonstrated by increased TFC. This finding may explain the recurrent angina and cardiovascular events of patients with MB. It may also explain the reversible myocardial perfusion defects which are associated with recurrent cardiovascular events in patients with MB. 

Myocardial bridging, thrombolysis in myocardial infarction, TIMI frame count, coronary flow, recurrent angina
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Primary Language en
Subjects Health Care Sciences and Services
Journal Section Original Articles

Orcid: 0000-0003-1939-1008
Author: Ekrem Aksu
Institution: Department of Cardiology, Kahramanmaraş Sütçü İmam University School of Medicine, Kahramanmaraş, Turkey
Country: Turkey

Orcid: 0000-0003-3853-5046
Author: Hakan Güneş (Primary Author)
Institution: Department of Cardiology, Kahramanmaraş Sütçü İmam University School of Medicine, Kahramanmaraş, Turkey
Country: Turkey


Publication Date: May 4, 2019

EndNote %0 The European Research Journal Increased TIMI frame count of coronary arteries in patients with myocardial bridging %A Ekrem Aksu , Hakan Güneş %T Increased TIMI frame count of coronary arteries in patients with myocardial bridging %D 2019 %J The European Research Journal %P -2149-3189 %V 5 %N 3 %R doi: 10.18621/eurj.388556 %U 10.18621/eurj.388556