Year 2018, Volume 1, Issue 3, Pages 18 - 18 2018-12-08

New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin

Stephen BLOOR [1] , Owen CATCHPOLE [2] , Kevin MITCHELL [3] , Rosemary WEBBY [4]

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Previous work has shown a number of phenolic components of NZ propolis demonstrate antiproliferative activity against certain human gastrointestinal cancer cell lines1.  Here we report on a series of acyl glycerols isolated from the non-polar fraction of propolis resin, which represent further bioactive constituents unrelated to the more usual phenolic compounds generally found in propolis. NZ propolis is sourced from poplar trees and the acyl glycerols have been shown to be present in the leaves and buds of some common poplars.  The compounds are a series of monoglycerides containing 3,8-dihydroxy fatty acids, many of which are further acylated with acetic acid residues. The dihydroxy fatty acids are C18 to C24, with the most abundant being C20 and C22. These acyl glycerols were found to have strong antiproliferative activity against three human gastro-intestinal cell lines, particularly gastric cancer cell line NCI-N87.

 

 

New Zealand Propolis, Acyl Glycerols, Antiproliferative
  • 1. Catchpole, O., Mitchell, K., Bloor, S., Davis, P., Suddes, A. (2015). Antiproliferative activity of New Zealand propolis and phenolic compounds vs human colorectal adenocarcinoma cells. Fitoterapia. 106, 3257: 167-174
Primary Language en
Journal Section 2nd Propolis Conference Special Issue
Authors

Author: Stephen BLOOR (Primary Author)

Author: Owen CATCHPOLE

Author: Kevin MITCHELL

Author: Rosemary WEBBY

Dates

Publication Date: December 8, 2018

Bibtex @conference paper { jan488626, journal = {Journal of Apitherapy and Nature}, issn = {}, eissn = {2667-4734}, address = {Oktay YILDIZ}, year = {2018}, volume = {1}, pages = {18 - 18}, doi = {}, title = {New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin}, key = {cite}, author = {BLOOR, Stephen and CATCHPOLE, Owen and MITCHELL, Kevin and WEBBY, Rosemary} }
APA BLOOR, S , CATCHPOLE, O , MITCHELL, K , WEBBY, R . (2018). New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin. Journal of Apitherapy and Nature, 1 (3), 18-18. Retrieved from http://dergipark.org.tr/jan/issue/40577/488626
MLA BLOOR, S , CATCHPOLE, O , MITCHELL, K , WEBBY, R . "New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin". Journal of Apitherapy and Nature 1 (2018): 18-18 <http://dergipark.org.tr/jan/issue/40577/488626>
Chicago BLOOR, S , CATCHPOLE, O , MITCHELL, K , WEBBY, R . "New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin". Journal of Apitherapy and Nature 1 (2018): 18-18
RIS TY - JOUR T1 - New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin AU - Stephen BLOOR , Owen CATCHPOLE , Kevin MITCHELL , Rosemary WEBBY Y1 - 2018 PY - 2018 N1 - DO - T2 - Journal of Apitherapy and Nature JF - Journal JO - JOR SP - 18 EP - 18 VL - 1 IS - 3 SN - -2667-4734 M3 - UR - Y2 - 2019 ER -
EndNote %0 Journal of Apitherapy and Nature New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin %A Stephen BLOOR , Owen CATCHPOLE , Kevin MITCHELL , Rosemary WEBBY %T New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin %D 2018 %J Journal of Apitherapy and Nature %P -2667-4734 %V 1 %N 3 %R %U
ISNAD BLOOR, Stephen , CATCHPOLE, Owen , MITCHELL, Kevin , WEBBY, Rosemary . "New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin". Journal of Apitherapy and Nature 1 / 3 (December 2018): 18-18.
AMA BLOOR S , CATCHPOLE O , MITCHELL K , WEBBY R . New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin. J.Apit.Nat.. 2018; 1(3): 18-18.
Vancouver BLOOR S , CATCHPOLE O , MITCHELL K , WEBBY R . New Antiproliferative Acyl Glycerols from New Zealand Propolis and Source Poplar Resin. Journal of Apitherapy and Nature. 2018; 1(3): 18-18.