Year 2018, Volume 1, Issue 3, Pages 63 - 63 2018-12-08

Caseinates Loaded with Red Propolis Extract

Isabel Cristina Celerino de Moraes PORTO [1] , Clinston Paulino de ALMEIDA [2] , Nataly Miranda do NASCIMENTO [3] , Amanda Barbosa WANDERLEY [4] , João V. Lessa de OLIVEIRA [5] , Felipe J. L. Barbosa dos SANTOS [6] , Valdemir da Costa SILVA [7] , Irinaldo Diniz BASÍLIO-JÚNIOR [8] , Giselda Macena LIRA [9] , Marta Maria da CONCEIÇÃO [10] , Ana Flávia Oliveira dos SANTOS [11] , Ticiano Gomes do NASCIMENTO [12]

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This work aimed to characterize microcapsules of caseinates loaded with red propolis extract (RPE) using different analytical and biological methods. Five compositions of microcapsules of caseinates loaded with RPE at concentrations between 10% and 50% were prepared using sodium casein from bovine milk as encapsulating agent and colloidal silicon dioxide as a flow agent. The caseinates were produced using colloidal dispersion technique and submitted to the spray-drying technique. The caseinates were characterized using SEM analysis, thermal analysis, FTIR, Fluorescence analysis, electrophoresis, dissolution studies, antioxidant and antibacterial activities.  SEM images showed spherical particles in the range from 3.24 μm to 20.5 μm.  FTIR, NMR spectra in solid-state and thermal analysis also demonstrated the encapsulation of the RPE. Dissolution study revealed limited to poor water-solubility of flavonoids in the compositions CSRPE18% and CSRPE28%, but good water solubility of naringenin in the compositions CSRPE35% and CSRPE50%. Excellent antioxidant activity and antibacterial activity were demonstrated only from CSRPE50% and CSRPE35% compositions. Thermal analysis, water-solubility dissolution assay and antioxidant activity have indicated a high protein binding between sodium casein and flavonoids from RPE in the CSRPE18% and CSRPE28% compositions resulting in a controlled release of the flavonoid. However immediate release of flavonoids in the compositions CSRPE35% and CSRPE50% was detected. The Fluorescence and thermal analysis allied to the dissolution, antioxidant and antibacterial tests were important analytical techniques to elucidate the interaction between flavonoid-protein and flavonoid release kinetic from caseinates soluble complex.

 

Acknowledgments. The authors are grateful to CNPq, CAPES, FINEP and FAPEAL for financial support.


 

Red Propolis, spray-drying, SEM analysis, FTIR
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Primary Language en
Journal Section 2nd Propolis Conference Special Issue
Authors

Author: Isabel Cristina Celerino de Moraes PORTO

Author: Clinston Paulino de ALMEIDA

Author: Nataly Miranda do NASCIMENTO

Author: Amanda Barbosa WANDERLEY

Author: João V. Lessa de OLIVEIRA

Author: Felipe J. L. Barbosa dos SANTOS

Author: Valdemir da Costa SILVA

Author: Irinaldo Diniz BASÍLIO-JÚNIOR

Author: Giselda Macena LIRA

Author: Marta Maria da CONCEIÇÃO

Author: Ana Flávia Oliveira dos SANTOS

Author: Ticiano Gomes do NASCIMENTO (Primary Author)

Dates

Publication Date: December 8, 2018

Bibtex @conference paper { jan489805, journal = {Journal of Apitherapy and Nature}, issn = {}, eissn = {2667-4734}, address = {Oktay YILDIZ}, year = {2018}, volume = {1}, pages = {63 - 63}, doi = {}, title = {Caseinates Loaded with Red Propolis Extract}, key = {cite}, author = {PORTO, Isabel Cristina Celerino de Moraes and ALMEIDA, Clinston Paulino de and NASCIMENTO, Nataly Miranda do and WANDERLEY, Amanda Barbosa and OLIVEIRA, João V. Lessa de and SANTOS, Felipe J. L. Barbosa dos and SILVA, Valdemir da Costa and BASÍLIO-JÚNIOR, Irinaldo Diniz and LIRA, Giselda Macena and CONCEIÇÃO, Marta Maria da and SANTOS, Ana Flávia Oliveira dos and NASCIMENTO, Ticiano Gomes do} }
APA PORTO, I , ALMEIDA, C , NASCIMENTO, N , WANDERLEY, A , OLIVEIRA, J , SANTOS, F , SILVA, V , BASÍLIO-JÚNIOR, I , LIRA, G , CONCEIÇÃO, M , SANTOS, A , NASCIMENTO, T . (2018). Caseinates Loaded with Red Propolis Extract. Journal of Apitherapy and Nature, 1 (3), 63-63. Retrieved from http://dergipark.org.tr/jan/issue/40577/489805
MLA PORTO, I , ALMEIDA, C , NASCIMENTO, N , WANDERLEY, A , OLIVEIRA, J , SANTOS, F , SILVA, V , BASÍLIO-JÚNIOR, I , LIRA, G , CONCEIÇÃO, M , SANTOS, A , NASCIMENTO, T . "Caseinates Loaded with Red Propolis Extract". Journal of Apitherapy and Nature 1 (2018): 63-63 <http://dergipark.org.tr/jan/issue/40577/489805>
Chicago PORTO, I , ALMEIDA, C , NASCIMENTO, N , WANDERLEY, A , OLIVEIRA, J , SANTOS, F , SILVA, V , BASÍLIO-JÚNIOR, I , LIRA, G , CONCEIÇÃO, M , SANTOS, A , NASCIMENTO, T . "Caseinates Loaded with Red Propolis Extract". Journal of Apitherapy and Nature 1 (2018): 63-63
RIS TY - JOUR T1 - Caseinates Loaded with Red Propolis Extract AU - Isabel Cristina Celerino de Moraes PORTO , Clinston Paulino de ALMEIDA , Nataly Miranda do NASCIMENTO , Amanda Barbosa WANDERLEY , João V. Lessa de OLIVEIRA , Felipe J. L. Barbosa dos SANTOS , Valdemir da Costa SILVA , Irinaldo Diniz BASÍLIO-JÚNIOR , Giselda Macena LIRA , Marta Maria da CONCEIÇÃO , Ana Flávia Oliveira dos SANTOS , Ticiano Gomes do NASCIMENTO Y1 - 2018 PY - 2018 N1 - DO - T2 - Journal of Apitherapy and Nature JF - Journal JO - JOR SP - 63 EP - 63 VL - 1 IS - 3 SN - -2667-4734 M3 - UR - Y2 - 2019 ER -
EndNote %0 Journal of Apitherapy and Nature Caseinates Loaded with Red Propolis Extract %A Isabel Cristina Celerino de Moraes PORTO , Clinston Paulino de ALMEIDA , Nataly Miranda do NASCIMENTO , Amanda Barbosa WANDERLEY , João V. Lessa de OLIVEIRA , Felipe J. L. Barbosa dos SANTOS , Valdemir da Costa SILVA , Irinaldo Diniz BASÍLIO-JÚNIOR , Giselda Macena LIRA , Marta Maria da CONCEIÇÃO , Ana Flávia Oliveira dos SANTOS , Ticiano Gomes do NASCIMENTO %T Caseinates Loaded with Red Propolis Extract %D 2018 %J Journal of Apitherapy and Nature %P -2667-4734 %V 1 %N 3 %R %U
ISNAD PORTO, Isabel Cristina Celerino de Moraes , ALMEIDA, Clinston Paulino de , NASCIMENTO, Nataly Miranda do , WANDERLEY, Amanda Barbosa , OLIVEIRA, João V. Lessa de , SANTOS, Felipe J. L. Barbosa dos , SILVA, Valdemir da Costa , BASÍLIO-JÚNIOR, Irinaldo Diniz , LIRA, Giselda Macena , CONCEIÇÃO, Marta Maria da , SANTOS, Ana Flávia Oliveira dos , NASCIMENTO, Ticiano Gomes do . "Caseinates Loaded with Red Propolis Extract". Journal of Apitherapy and Nature 1 / 3 (December 2018): 63-63.
AMA PORTO I , ALMEIDA C , NASCIMENTO N , WANDERLEY A , OLIVEIRA J , SANTOS F , SILVA V , BASÍLIO-JÚNIOR I , LIRA G , CONCEIÇÃO M , SANTOS A , NASCIMENTO T . Caseinates Loaded with Red Propolis Extract. J.Apit.Nat.. 2018; 1(3): 63-63.
Vancouver PORTO I , ALMEIDA C , NASCIMENTO N , WANDERLEY A , OLIVEIRA J , SANTOS F , SILVA V , BASÍLIO-JÚNIOR I , LIRA G , CONCEIÇÃO M , SANTOS A , NASCIMENTO T . Caseinates Loaded with Red Propolis Extract. Journal of Apitherapy and Nature. 2018; 1(3): 63-63.