Year 2018, Volume 21, Issue 3, Pages 225 - 229 2018-12-02

Romatizmal Mitral Stenozlu Hastalarda Perkütan Mitral Balon Valvüloplastinin P Dalga Dispersiyonu Üzerine Etkisi
Impact of Percutaneous Mitral Balloon Valvuloplasty on P-Wave Dispersion in Patients with Rheumatic Mitral Stenosis

Hicaz Zencirkıran Ağuş [1] , Serkan Kahraman [2]

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Giriş: P dalga dispersiyonu (PDD), farklı elektrokardiyografi (EKG) leadlerinden heterojen atriyal iletiyi yansıttığına inanılan yeni bir elektrokardiyografik indekstir. Mitral stenoz (MS), atriyal fibrilasyon (AF)un bir göstergesi olan artmış PDD ile ilişkilidir. Çalışmamız başarılı perkütan mitral balon valvüloplasti (PMBV)nin bu parametreler üzerine olan etkisini incelemek için tasarlandı.

Hastalar ve Yöntem: Orta ve ciddi romatizmal mitral stenozu olan 70 (%98 kadın, ortalama yaş 44 ± 12) hasta ve 60 (%95.7 kadın, ortalama yaş 45 ± 11) sağlıklı kontrol grubu çalışmaya alındı. PMBV’den 1 gün önce ve yapıldıktan sonra 72 saat içinde 12 derivasyonlu EKG çekilerek maksimum ve minimum P dalga süresi, PDD hesaplandı.

Bulgular: Maksimum P dalga süresi  ve PDD MS hastalarında kontrol grubuna göre anlamlı olarak fazla bulundu (p< 0.001). Pmax [142 (120-170) vs. 130 (110-164), p< 0.001] ve PDD [45 (30-69) vs. 35 (16-57), p< 0.00], PMBV sonrası akut dönemde azaldı (p< 0.001). Diğer yandan işlemin minimum P dalga süresi üzerine anlamlı etkisi olmadı (p= 0.111).

Sonuç: Çalışmamızda MS’li hastalarda Pmax ve PDD’nin sağlıklı kontrol grubuna göre anlamlı olarak fazla olduğunu ve başarılı PMBV sonrası anlamlı derecede azaldığını gösterdik. MS’li hastalarda AF ile atriyal ileti velositeleri arasındaki ilişkiyi doğrulamak için prospektif uzun dönem takipli çalışmalara ihtiyaç vardır.

Introduction: P-wave dispersion (PWD) is a new electrocardiographic (ECG) index believed to reflect heterogeneous atrial conduction with ECG leads of different orientation. Mitral stenosis (MS) is associated with increased PWD, which are markers of atrial fibrillation (AF) risk. The aim of the present study was to assess the immediate effect of successful percutaneous mitral balloon valvuloplasty (PMBV) on these parameters.

Patients and Methods: Seventy patients (98% females, aged 44 ± 12 years) with moderate or severe rheumatic MS and 60 healthy volunteers (95.7% females, aged 45 ± 11 years) as a control group were enrolled in the study. 12-Lead ECGs were recorded for each patient 1 day before PMBV to evaluate baseline maximum and minimum P-wave duration and PWD and repeated within 72 h.

Results: The maximum P-wave duration (Pmax) and PWD in patients with MS were found to be significantly higher than those in the control group (p< 0.001). ECG parameters of Pmax (142 (120-170) vs. 130 (110-164), p< 0.001) and PWD [45 (30-69) vs. 35 (16-57), p< 0.001] decreased in the acute period of PMBV (p< 0.001). On the other hand, the procedure had no significant effect on minimum P-wave duration (p= 0.111).

Conclusion: Our study has shown that Pmax and PWD were significantly higher in patients with MS than in healthy control subjects, and they decreased significantly after successful PMBV. Further prospective long-term studies are needed to confirm the relationship between atrial conduction velocities and development of AF in patients with MS.
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Primary Language en
Subjects Medicine
Journal Section Original Investigations
Authors

Author: Hicaz Zencirkıran Ağuş (Primary Author)

Author: Serkan Kahraman

Bibtex @research article { khj495086, journal = {Koşuyolu Heart Journal}, issn = {2149-2972}, eissn = {2149-2980}, address = {Kartal Koşuyolu Yüksek İhtisas EAH}, year = {2018}, volume = {21}, pages = {225 - 229}, doi = {}, title = {Impact of Percutaneous Mitral Balloon Valvuloplasty on P-Wave Dispersion in Patients with Rheumatic Mitral Stenosis}, key = {cite}, author = {Zencirkıran Ağuş, Hicaz and Kahraman, Serkan} }
APA Zencirkıran Ağuş, H , Kahraman, S . (2018). Impact of Percutaneous Mitral Balloon Valvuloplasty on P-Wave Dispersion in Patients with Rheumatic Mitral Stenosis. Koşuyolu Heart Journal, 21 (3), 225-229. Retrieved from http://dergipark.org.tr/khj/issue/40963/495086
MLA Zencirkıran Ağuş, H , Kahraman, S . "Impact of Percutaneous Mitral Balloon Valvuloplasty on P-Wave Dispersion in Patients with Rheumatic Mitral Stenosis". Koşuyolu Heart Journal 21 (2018): 225-229 <http://dergipark.org.tr/khj/issue/40963/495086>
Chicago Zencirkıran Ağuş, H , Kahraman, S . "Impact of Percutaneous Mitral Balloon Valvuloplasty on P-Wave Dispersion in Patients with Rheumatic Mitral Stenosis". Koşuyolu Heart Journal 21 (2018): 225-229
RIS TY - JOUR T1 - Impact of Percutaneous Mitral Balloon Valvuloplasty on P-Wave Dispersion in Patients with Rheumatic Mitral Stenosis AU - Hicaz Zencirkıran Ağuş , Serkan Kahraman Y1 - 2018 PY - 2018 N1 - DO - T2 - Koşuyolu Heart Journal JF - Journal JO - JOR SP - 225 EP - 229 VL - 21 IS - 3 SN - 2149-2972-2149-2980 M3 - UR - Y2 - 2019 ER -
EndNote %0 Koşuyolu Heart Journal Impact of Percutaneous Mitral Balloon Valvuloplasty on P-Wave Dispersion in Patients with Rheumatic Mitral Stenosis %A Hicaz Zencirkıran Ağuş , Serkan Kahraman %T Impact of Percutaneous Mitral Balloon Valvuloplasty on P-Wave Dispersion in Patients with Rheumatic Mitral Stenosis %D 2018 %J Koşuyolu Heart Journal %P 2149-2972-2149-2980 %V 21 %N 3 %R %U
ISNAD Zencirkıran Ağuş, Hicaz , Kahraman, Serkan . "Impact of Percutaneous Mitral Balloon Valvuloplasty on P-Wave Dispersion in Patients with Rheumatic Mitral Stenosis". Koşuyolu Heart Journal 21 / 3 (December 2018): 225-229.