Tekrarlayan Şüpheli Senkoplu Hastalarda Çift Doz Dilaltı Nitrogliserin ile Yapılan Eğik Masa Testinin Reprodusibilitesi

Yıl 2019, Cilt: 22 Sayı: 2, 107 - 111, 15.08.2019

Çayan Çakır

Öz

Giriş: Eğik masa
testi senkop şüpheli hastalarda sıkça kullanılan bir testtir. Testin tanısal
değeri ve reprodusibilitesi hakkında karşıt görüşler mevcuttur. Çeşitli
serilerde pozitif bir testin reprodusibilitesi %36-90, negatif

bir testin
reprodusibilitesi ise %85-100 arasında bildirilmiştir. Biz bu çalışmada eğik
masa testinin güncel

reprodusibilitesini
araştırmayı hedefledik.

 

Hastalar ve Yöntem:
Hastanemizde Mayıs 2017-Ocak 2019 tarihleri arasında çift doz sublingual sprey
nitrogliserin ile test uygulanan tüm ardışık hastalar çalışmaya dahil edilmek
üzere değerlendirildi. Çalışmaya

katılmayı kabul eden
hastalar ilk testten 1-7 gün sonra ikinci bir teste alındılar.

 

Bulgular: Toplam 135
hasta [76 erkek (%56.3), 59 kadın (%43.7)] çalışmaya dahil edildi. Yaş aralığı
18-

61 ve ortalama yaş (±
SD) 32 ± 10.85 idi. İlk testte 81 (%60.0) hastada pozitif sonuç, 51 (%37.8)
hastada

negatif sonuç ve 3
(%2.2) hastada nitrata abartılı yanıt saptandı. İkinci testte ise 75 (%55.6)
hastada pozitif,

60 (%44.4) hastada
negatif sonuç saptandı. Pozitif reprodusibilite %85.2, negatif reprodusibilite
%88.2 ve

toplam
reprodusibilite %86.4 idi. Dilaltı nitratın yan etkilerine bağlı olarak test
hiçbir hastada sonlandırılmadı.

 

Sonuç: Seçilmiş
hastalarda çift doz dilaltı sprey nitrogliserin ile yapılan eğik masa testinin
güncel reprodusibilitesi yüksektir ve çift doz nitrogliserin kullanımı
güvenilir olabilir.

Anahtar Kelimeler

Senkop, eğik masa testi, eprodusibilite

Reproducibility of Tilt-Table Test Potentiated with Double Dose Sublingual Nitroglycerin in Patients with Suspected Recurrent Syncopal Episodes

Öz

Introduction:
Tilt-table test (TT) is a noninvasive and safe test used for the diagnosis of
patients with syncope. Currently, there are controversies about the diagnostic
utility and reproducibility of TT. The reproducibility of TT has been reported
within a wide range from 36% to 90% for a positive test and from 85% to 100%
for a negative test. The aim of the present study was to investigate the
current reproducibility of TT.

 

Patients and Methods:
All consecutive patients who underwent TT with double dose spray nitroglycerin
due to suspected reflex syncope between May 2017 and January 2019 at our
hospital were evaluated. Patients underwent a second TT within 1-7 days
following the initial test.

 

Results: A total of
135 (76 female, 56.3% and 59 male, 43.7%) patients aged 18-61 (mean (± SD) 32 ±
10.85) years were included in the study. In the first test, 81 (60.0%) patients
had a positive response, 51 (37.8%) patients had a negative response, and 3
(2.2%) patients had an exaggerated response. In the repeated test, 75 (55.6%)
patients had a positive response, and 60 (44.4%) patients had a negative
response. The reproducibility of a positive tilt test was 85.2%, whereas the
reproducibility of a negative tilt test was 88.2%. Overall reproducibility was
86.4%.

 

Conclusion: In
selected patients, TT with double dose sublingual spray nitroglycerin has a
high reproducibility. Double dose sublingual spray nitroglycerin might be used
for potentiating TT with acceptable safety.

Anahtar Kelimeler

Syncope, tilt-table test, reproducibility

Kaynakça

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