A Rare Complication of Wilson's Disease: Hepatocellular Carcinoma

Year 2022, , 328 - 331, 30.12.2022

Laleş Yanık Göktürk , Çiğdem Budak Ece

https://doi.org/10.47493/abantmedj.1160858

Abstract

Wilson's disease, which is a disorder of copper metabolism, its clinical spectrum is quite wide. It gives specific findings to the organ it accumulates. These patients may present with asymptomatic transaminase elevation in the gastroenterology outpatient clinic, as well as cirrhosis and hepatocellular carcinoma, which are advanced complications. In the case report, we present a patient who was diagnosed with HCC (hepatocellular carcinoma) as a result of advanced research due to the high AFP (alpha-feto protein) during routine follow-up of a Wilson patient who was being followed up due to cirrhosis.

Keywords

Hepatocelüler Carcinoma, Cirrhosis

Wilson Hastalığının Nadir Bir Komplikasyonu: Hepatoselüler Karsinom

Abstract

Bakır metabolizma bozukluğu olan Wilson hastalığı, klinik spektrumu oldukça geniştir. Birikim yaptığı organa spesifik bulgu vermektedir. Bu hastalar gastroenteroloji polikliniğinde asemptomatik transaminaz yüksekliği ile başvurabileceği gibi, ileri komplikasyonlardan olan siroz ve hepatoselüler karsinom şeklinde de prezente olabilmektedir. Olgu sunumunda siroz nedeniyle takipli olan Wilson hastasının rutin takiplerinde AFP (alfa-feto protein) yüksekliği olması nedeniyle ileri araştırmalar sonucunda HCC (hepatoselüler karsinom) tanısı alan hastayı sunmaktayız.

Keywords

Wilson, Hepatoselüler Karsinom, Siroz, Hepatocelüler Carcinoma, Cirrhosis

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