Evaluation of Colistin Nephrotoxicity in Intensive Care Diseases of Patient

Year 2018, , 10 - 14, 01.01.2018

Fatma Kaplan Efe Fatma Ayerden Ebinç Serdar Karakaya , İbrahim Karadağ Murat Eser Oktay Ünsal Aysun Aybal Kutlugün Esin Beyan

https://doi.org/10.5505/abantmedj.2018.39306

Abstract

INTRODUCTION: Evaluation of the development of nephrotoxicity and the factors affecting it in patients treated with colistin theraphMETHODS: 51 patients who received colistin treatment were divided into two groups as nephrotoxicity developing and nondeveloping. Demographic and laboratory data between the groups were comparedRESULTS: Colistin induced nephrotoxicity was detected in 64.7% of the patients. Patients who developed nephrotoxicity had a higher mortality rate p: 0.01 .DISCUSSION AND CONCLUSION: Nephrotoxicity of colistin should be noted in ICU patients.

Keywords

Colistin, nephrotoxicity, intensive care unit

Yoğun Bakım Hastalarında Kolistin Nefrotoksisitesinin Değerlendirilmesi

Abstract

GİRİŞ ve AMAÇ: Bu çalışmanın amacı, Kolistin verilen hastalarda nefrotoksisite gelişiminin ve bunu etkileyen faktörlerin değerlendirilmesidir. YÖNTEM ve GEREÇLER: Kolistin verilen 51 hasta nefrotoksiste gelişen ve gelişmeyenler olarak iki gruba ayrıldı. Gruplar, demografik özellikler ve laboratuar verileri yönünden karşılaştırıldı.BULGULAR: Hastaların %64,7’sinde kolistine bağlı nefrotoksisite saptandı. Nefrotoksisite gelişen hastaların ölüm oranı daha yüksek bulundu p: 0,01 .TARTIŞMA ve SONUÇ: Yoğun bakım hastalarında kolistin nefrotoksisitesine dikkat edilmelidir.

Keywords

Kolistin, nefrotoksisite, yoğun bakım

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