Efficacy of Photodynamic Therapy Versus Intravitreal Bevacizumab Injection for Chronic Central Serous Chorioretinopathy

Abstract

Objective: To compare the efficacy of photodynamic therapy PDT versus intravitreal bevacizumab IVB injection for the treatment of chronic central serous chorioretinopathy CSC . Method: The medical records of 16 eyes of 15 patients who received PDT n=9 or IVB n=6 for symptomatic chronic central serous chorioretinopathy CSC were retrospectively reviewed. Best-corrected visual acuity BCVA , central macular thickness CMT , and subretinal fluid SRF volume were compared between the two patient groups at baseline and at 1,3 and 6 months after treatment. Results: Median BCVA was similar in both groups at all time points p>0.05 . The reduction of CMT was significant at the 1st and 3rd month p

Keywords

• Chronic central serous chorioretinopathy, photodynamic therapy, intravitreal bevacizumab.

Kronik Santral Seröz Koryoretinopatide Fotodinamik Tedavinin ve İntravitreal Bevacizumab Enjeksiyonunun Etkinliği

Abstract

Amaç: Kronik santral seröz koryoretinopati SSR tedavisinde fotodinamik tedavi PDT ile intravitreal bevacizumab’ın IVB etkinliğini karşılaştırmak. Yöntem: Semptomatik kronik SSR nedeniyle PDT n=9 veya IVB n=6 uygulanmış 15 hastanın 16 gözüne ait dosyalar retrospektif olarak incelendi. İki grup, en iyi düzeltilmiş görme keskinliği EDGK , santral makülar kalınlık SMK ve subretinal sıvı SRS volümü açısından tedavi sonrası 1., 3. ve 6. aylarda karşılaştırıldı. Bulgular: Tüm zaman dilimlerinde, ortanca EDGK açısından her iki grup benzerdi p>0.05 . SMK azalması açısından 1. ve 3. aylarda iki grup arasında anlamlı fark izlenirken p

Keywords

• Kronik santral seröz koryoretinopati, fotodinamik tedavi, intravitreal bevacizumab.

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