Burden of Disease in Obesity through the Window of Metabolic Syndrome

Abstract

INTRODUCTION: In terms of quality of life, it was aimed to reveal the relationship between obesity and the presence of metabolic syndrome in prediabetic or normoglycemic people. METHODS: A total of 159 patients, 18-65 years of age, were included in the study. Body mass index (BMI) values of 30 kg/m² and above were accepted as obesity. Quality of life was evaluated with short form-36 (SF-36). RESULTS: According to the SF-36 quality of life assessment of all patients; the median values of physical component, mental component and total score were found to be significantly lower in patients with obesity than those without obesity (p=0.006, p=0.040, p=0.009, respectively). In the subgroup analysis of individuals without metabolic syndrome, according to the SF-36 quality of life assessment; the median values of physical component, mental component and total score were similar in patients with obesity compared to those without obesity (p=0.379, p=0.574, p=0.525, respectively). Similarly, according to the SF-36 quality of life assessment of all patients; the median values of physical component, mental component and total score were found to be significantly lower in patients with MetS than those without MetS (p<0.001, p<0.001, p<0.001, respectively). In the subgroup analysis of individuals with obesity, according to the SF-36 quality of life assessment; the median values of physical component, mental component and total score were similar in patients with MetS compared to those without MetS (p=0.001, p=0.009, p=0.003, respectively). DISCUSSION and CONCLUSION: Through this study, it has been shown again that the quality of life is reduced in those with obesity. In addition, our findings show that the reduction in the quality of life of patients with obesity mainly points to the presence of MetS.

Keywords

• Metabolic syndrome
• obesity
• global burden of disease

Metabolik Sendrom Penceresinden Obezitede Hastalık Yükü

Abstract

INTRODUCTION: In terms of quality of life, it was aimed to reveal the relationship between obesity and the presence of metabolic syndrome in prediabetic or normoglycemic people. METHODS: A total of 159 patients, 18-65 years of age, were included in the study. Body mass index (BMI) values of 30 kg/m² and above were accepted as obesity. Quality of life was evaluated with short form-36 (SF-36). RESULTS: According to the SF-36 quality of life assessment of all patients; the median values of physical component, mental component and total score were found to be significantly lower in patients with obesity than those without obesity (p=0.006, p=0.040, p=0.009, respectively). In the subgroup analysis of individuals without metabolic syndrome, according to the SF-36 quality of life assessment; the median values of physical component, mental component and total score were similar in patients with obesity compared to those without obesity (p=0.379, p=0.574, p=0.525, respectively). Similarly, according to the SF-36 quality of life assessment of all patients; the median values of physical component, mental component and total score were found to be significantly lower in patients with MetS than those without MetS (p<0.001, p<0.001, p<0.001, respectively). In the subgroup analysis of individuals with obesity, according to the SF-36 quality of life assessment; the median values of physical component, mental component and total score were similar in patients with MetS compared to those without MetS (p=0.001, p=0.009, p=0.003, respectively). DISCUSSION and CONCLUSION: Through this study, it has been shown again that the quality of life is reduced in those with obesity. In addition, our findings show that the reduction in the quality of life of patients with obesity mainly points to the presence of MetS.

Keywords

• Metabolik sendrom
• obezite
• global hastalık yükü

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